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Published in: Archives of Gynecology and Obstetrics 6/2011

01-06-2011 | Materno-fetal Medicine

The clinical management of hyperemesis gravidarum

Author: Shipra Sonkusare

Published in: Archives of Gynecology and Obstetrics | Issue 6/2011

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Abstract

Hyperemesis gravidarum is a severe and disabling condition with potentially life-threatening complications. It is likely to have a multifactorial etiology which contributes to the difficulty in treatment. Treatment is supportive with correction of dehydration and electrolyte disturbance, antiemetic therapy, prevention and treatment of complications like Wernicke’s encephalopathy, osmotic demyelination syndrome, thromboembolism, and good psychological support. There are abundant data on the safety of antihistamines, phenothiazines, and metoclopromide in early pregnancy and treatment should therefore not be withheld on the basis of teratogenicity concerns. Thiamine replacement is indicated in hyperemesis gravidarum to prevent development of Wernicke’s encephalopathy.
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Metadata
Title
The clinical management of hyperemesis gravidarum
Author
Shipra Sonkusare
Publication date
01-06-2011
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 6/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-011-1877-y

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