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World Journal of Urology
Published in: World Journal of Urology 1/2010

01-02-2010 | Topic Paper

The clinical effectiveness of transurethral incision of the prostate: a systematic review of randomised controlled trials

Authors: Tania Lourenco, Matthew Shaw, Cynthia Fraser, Graeme MacLennan, James N’Dow, Robert Pickard

Published in: World Journal of Urology | Issue 1/2010

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Abstract

Purpose

Transurethral incision of the prostate gland (TUIP) is perceived as a less morbid surgical alternative to standard transurethral resection of the prostate gland (TURP) for treatment of symptomatic mild to moderate benign prostate enlargement (BPE). We aimed to evaluate comparative clinical effectiveness of the two procedures.

Methods

Systematic review and meta-analysis of short- and long-term data from randomised controlled trials comparing TUIP with TURP.

Results

This review considered data from 795 randomised participants across 10 RCTs of moderate to poor quality 8 of which stated an upper limit for prostate size. No difference in the degree of symptomatic improvement was seen between the two procedures. Improvement in peak urine flow rate was lower for TUIP compared to TURP whilst the rate of blood transfusion and TUR syndrome was higher after TURP. Urinary retention, urinary tract infection, strictures and incontinence did not differ between the two approaches, although clinically important differences could not be ruled-out. TUIP was associated with a shorter duration of operation and length of hospital stay but a higher re-operation rate.

Conclusion

TUIP and TURP appear to offer equivalent symptomatic improvement for men with mild to moderate BPE. Choosing TUIP involves a trade-off between the lower risk of peri-operative morbidity and the higher risk of subsequent re-operation.
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Metadata
Title
The clinical effectiveness of transurethral incision of the prostate: a systematic review of randomised controlled trials
Authors
Tania Lourenco
Matthew Shaw
Cynthia Fraser
Graeme MacLennan
James N’Dow
Robert Pickard
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
World Journal of Urology / Issue 1/2010
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-009-0496-8

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