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01-09-2010 | Review

The Cerebellum and Basal Ganglia are Interconnected

Authors: Andreea C. Bostan, Peter L. Strick

Published in: Neuropsychology Review | Issue 3/2010

Abstract

The cerebellum and the basal ganglia are major subcortical nuclei that control multiple aspects of behavior largely through their interactions with the cerebral cortex. Discrete multisynaptic loops connect both the cerebellum and the basal ganglia with multiple areas of the cerebral cortex. Interactions between these loops have traditionally been thought to occur mainly at the level of the cerebral cortex. Here, we review a series of recent anatomical studies in nonhuman primates that challenge this perspective. We show that the anatomical substrate exists for substantial interactions between the cerebellum and the basal ganglia. Furthermore, we discuss how these pathways may provide a useful framework for understanding cerebellar contributions to the manifestation of two prototypical basal ganglia disorders, Parkinson’s disease and dystonia.

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Title: The Cerebellum and Basal Ganglia are Interconnected
Authors: Andreea C. Bostan
Peter L. Strick
Publication date: 01-09-2010
Publisher: Springer US
Published in: Neuropsychology Review / Issue 3/2010
Print ISSN: 1040-7308
Electronic ISSN: 1573-6660
DOI: https://doi.org/10.1007/s11065-010-9143-9

At a glance: The STEP trials

Springer Medicine

The Cerebellum and Basal Ganglia are Interconnected

Abstract

At a glance: The STEP trials

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Abstract

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