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Head & Face Medicine

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Open Access 01-12-2008 | Case report

The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case

Authors: Tobias Ettl, Johannes Kleinheinz, Ravi Mehrotra, Stephan Schwarz, Torsten Eugen Reichert, Oliver Driemel

Published in: Head & Face Medicine | Issue 1/2008

Abstract

Background

With the 2005 WHO classification of salivary gland tumours and its increasingly recognized diagnostic entities, the frequency of adenocarcinoma (NOS) has decreased significantly.

Case presentation

This paper describes a fast growing adenocarcinoma (NOS), originating from the minor salivary glands of the left buccal mucosa with a rapid onset of multiple local and distant metastases, especially in the lung. A lung primary was unlikely as the tumour was characterized by positivity for cytokeratin 20 and negativity for the thyroid transcription factor-1 protein (TTF-1) in immunohistochemistry.

Conclusion

A rare case of an adenocarcinoma (NOS) of the minor salivary glands with a rapid development and an unfavourable clinical course is reported. It shows that additional immunohistochemical analysis can decisively contribute to determine the site of the primary tumour in cases with unknown primary.

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Title: The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case
Authors: Tobias Ettl
Johannes Kleinheinz
Ravi Mehrotra
Stephan Schwarz
Torsten Eugen Reichert
Oliver Driemel
Publication date: 01-12-2008
Publisher: BioMed Central
Published in: Head & Face Medicine / Issue 1/2008
Electronic ISSN: 1746-160X
DOI: https://doi.org/10.1186/1746-160X-4-16

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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