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01-07-2008 | CARDIOVASCULAR DISEASE

The association of the metabolic syndrome with QTc interval in NHANES III

Authors: Mohammed F. Faramawi, Rachel P. Wildman, Jeanette Gustat, Janet Rice, Mohammed Y. Abdul Kareem

Published in: European Journal of Epidemiology | Issue 7/2008

Abstract

Purpose To examine the relationship of metabolic syndrome with corrected QT interval duration. Methods In a cross-sectional analysis of NHANES III, a representative sample of the adult US population, 3,495 individuals aged ≥40 years were categorized as having metabolic syndrome and not having metabolic syndrome as defined by ATP III. QT interval was measured from the standard 12-lead electrocardiogram. Results A weighted multi-linear regression analysis adjusted for age, gender, serum calcium, and potassium showed that metabolic syndrome was significantly associated with a corrected QT interval in milliseconds. The adjusted Beta coefficient and its corresponding standard error were (4.48 milliseconds, 0.95 milliseconds, P < 0.01). Conclusion These data indicate that metabolic syndrome is independently associated with a corrected QT interval duration. This study calls for careful ECG monitoring among persons with metabolic syndrome for early detection of a long corrected QT interval in order to prevent severe and often fatal arrhythmias.

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Title: The association of the metabolic syndrome with QTc interval in NHANES III
Authors: Mohammed F. Faramawi
Rachel P. Wildman
Jeanette Gustat
Janet Rice
Mohammed Y. Abdul Kareem
Publication date: 01-07-2008
Publisher: Springer Netherlands
Published in: European Journal of Epidemiology / Issue 7/2008
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI: https://doi.org/10.1007/s10654-008-9252-4

At a glance: The STEP trials

Springer Medicine

The association of the metabolic syndrome with QTc interval in NHANES III

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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