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Published in: BMC Health Services Research 1/2013

Open Access 01-12-2013 | Research article

The association of smoking status with healthcare utilisation, productivity loss and resulting costs: results from the population-based KORA F4 study

Authors: Margarethe Wacker, Rolf Holle, Joachim Heinrich, Karl-Heinz Ladwig, Annette Peters, Reiner Leidl, Petra Menn

Published in: BMC Health Services Research | Issue 1/2013

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Abstract

Background

Smoking is seen as the most important single risk to health today, and is responsible for a high financial burden on healthcare systems and society. This population-based cross-sectional study compares healthcare utilisation, direct medical costs, and costs of productivity losses for different smoking groups: current smokers, former smokers, and never smokers.

Methods

Using a bottom-up approach, data were taken from the German KORA F4 study (2006/2008) on self-reported healthcare utilisation and work absence due to illness for 3,071 adults aged 32-81 years. Unit costs from a societal perspective were applied to utilisation. Utilisation and resulting costs were compared across different smoking groups using generalised linear models to adjust for age, sex, education, alcohol consumption and physical activity.

Results

Average annual total costs per survey participant were estimated as €3,844 [95% confidence interval: 3,447-4,233], and differed considerably between smoking groups with never smokers showing €3,237 [2,802-3,735] and former smokers causing €4,398 [3,796-5,058]. There was a positive effect of current and former smoking on the utilisation of healthcare services and on direct and indirect costs. Total annual costs were more than 20% higher (p<0.05) for current smokers and 35% higher (p<0.01) for former smokers compared with never smokers, which corresponds to annual excess costs of €743 and €1,108 per current and former smoker, respectively.

Conclusions

Results indicate that excess costs for current and former smokers impose a large burden on society, and that previous top-down cost approaches produced lower estimates for the costs of care for smoking-related diseases. Efforts must be focused on prevention of smoking to achieve sustainable containment on behalf of the public interest.
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Literature
1.
go back to reference Beaglehole R, Bonita R, Horton R, Adams C, Alleyne G, Asaria P, Baugh V, Bekedam H, Billo N, Casswell S, et al: Priority actions for the non-communicable disease crisis. Lancet. 2011, 377 (9775): 1438-1447. 10.1016/S0140-6736(11)60393-0.CrossRefPubMed Beaglehole R, Bonita R, Horton R, Adams C, Alleyne G, Asaria P, Baugh V, Bekedam H, Billo N, Casswell S, et al: Priority actions for the non-communicable disease crisis. Lancet. 2011, 377 (9775): 1438-1447. 10.1016/S0140-6736(11)60393-0.CrossRefPubMed
2.
go back to reference U.S. Department of Health and Human Services: The Health Consequences of Smoking: A Report of the Surgeon General. 2004, Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health U.S. Department of Health and Human Services: The Health Consequences of Smoking: A Report of the Surgeon General. 2004, Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health
3.
go back to reference Jia H, Lubetkin EI: Trends in quality-adjusted life-years lost contributed by smoking and obesity. Am J Prevent Med. 2010, 38 (2): 138-144. 10.1016/j.amepre.2009.09.043.CrossRef Jia H, Lubetkin EI: Trends in quality-adjusted life-years lost contributed by smoking and obesity. Am J Prevent Med. 2010, 38 (2): 138-144. 10.1016/j.amepre.2009.09.043.CrossRef
4.
go back to reference Vogl M, Wenig C, Leidl R, Pokhrel S: Smoking and health-related quality of life in English general population: implications for economic evaluations. BMC Public Health. 2012, 12 (1): 203-10.1186/1471-2458-12-203.CrossRefPubMedPubMedCentral Vogl M, Wenig C, Leidl R, Pokhrel S: Smoking and health-related quality of life in English general population: implications for economic evaluations. BMC Public Health. 2012, 12 (1): 203-10.1186/1471-2458-12-203.CrossRefPubMedPubMedCentral
5.
go back to reference World Health Organization: WHO report on the global tobacco epidemic, 2009: Implementing smoke-free environments. 2009, Geneva: World Health OrganizationCrossRef World Health Organization: WHO report on the global tobacco epidemic, 2009: Implementing smoke-free environments. 2009, Geneva: World Health OrganizationCrossRef
6.
go back to reference Max W: The financial impact of smoking on health-related costs: a review of the literature. Am J Health Promot. 2001, 15 (5): 321-331. 10.4278/0890-1171-15.5.321.CrossRefPubMed Max W: The financial impact of smoking on health-related costs: a review of the literature. Am J Health Promot. 2001, 15 (5): 321-331. 10.4278/0890-1171-15.5.321.CrossRefPubMed
7.
go back to reference Bank W: Curbing the Epidemic: Governments and the Economics of Tobacco Control. 1999, Washington: The World BankCrossRef Bank W: Curbing the Epidemic: Governments and the Economics of Tobacco Control. 1999, Washington: The World BankCrossRef
8.
go back to reference Lampert T: Smoking - recent trends in adults. GBE kompakt 2 (4) - Zahlen und Trends aus der Gesundheitsberichterstattung des Bundes. 2011, Berlin: Robert Koch-Institut Lampert T: Smoking - recent trends in adults. GBE kompakt 2 (4) - Zahlen und Trends aus der Gesundheitsberichterstattung des Bundes. 2011, Berlin: Robert Koch-Institut
9.
go back to reference Kahende JW, Adhikari B, Maurice E, Rock V, Malarcher A: Disparities in health care utilization by smoking status - NHANES 1999-2004. Int J Environmen Res Public Health. 2009, 6 (3): 1095-1106. 10.3390/ijerph6031095.CrossRef Kahende JW, Adhikari B, Maurice E, Rock V, Malarcher A: Disparities in health care utilization by smoking status - NHANES 1999-2004. Int J Environmen Res Public Health. 2009, 6 (3): 1095-1106. 10.3390/ijerph6031095.CrossRef
10.
go back to reference Wagner EH, Curry SJ, Grothaus L, Saunders KW, McBride CM: The impact of smoking and quitting on health care use. Arch Int Med. 1995, 155 (16): 1789-1795. 10.1001/archinte.1995.00430160133013.CrossRef Wagner EH, Curry SJ, Grothaus L, Saunders KW, McBride CM: The impact of smoking and quitting on health care use. Arch Int Med. 1995, 155 (16): 1789-1795. 10.1001/archinte.1995.00430160133013.CrossRef
11.
go back to reference Lundborg P: Does smoking increase sick leave? Evidence using register data on Swedish workers. Tobacco Control. 2007, 16 (2): 114-118. 10.1136/tc.2006.017798.CrossRefPubMedPubMedCentral Lundborg P: Does smoking increase sick leave? Evidence using register data on Swedish workers. Tobacco Control. 2007, 16 (2): 114-118. 10.1136/tc.2006.017798.CrossRefPubMedPubMedCentral
12.
go back to reference Robbins AS, Fonseca VP, Chao SY, Coil GA, Bell NS, Amoroso PJ: Short term effects of cigarette smoking on hospitalisation and associated lost workdays in a young healthy population. Tobacco Control. 2000, 9 (4): 389-396. 10.1136/tc.9.4.389.CrossRefPubMedPubMedCentral Robbins AS, Fonseca VP, Chao SY, Coil GA, Bell NS, Amoroso PJ: Short term effects of cigarette smoking on hospitalisation and associated lost workdays in a young healthy population. Tobacco Control. 2000, 9 (4): 389-396. 10.1136/tc.9.4.389.CrossRefPubMedPubMedCentral
13.
go back to reference Weng SF, Ali S, Leonardi-Bee J: Smoking and absence from work: systematic review and meta-analysis of occupational studies. Addiction. 2013, 108 (2): 307-319. 10.1111/add.12015.CrossRefPubMed Weng SF, Ali S, Leonardi-Bee J: Smoking and absence from work: systematic review and meta-analysis of occupational studies. Addiction. 2013, 108 (2): 307-319. 10.1111/add.12015.CrossRefPubMed
14.
go back to reference Fishman PA, Khan ZM, Thompson EE, Curry SJ: Health care costs among smokers, former smokers, and never smokers in an HMO. Health Serv Res. 2003, 38 (2): 733-749. 10.1111/1475-6773.00142.CrossRefPubMedPubMedCentral Fishman PA, Khan ZM, Thompson EE, Curry SJ: Health care costs among smokers, former smokers, and never smokers in an HMO. Health Serv Res. 2003, 38 (2): 733-749. 10.1111/1475-6773.00142.CrossRefPubMedPubMedCentral
15.
go back to reference Kiiskinen U, Vartiainen E, Puska P, Pekurinen M: Smoking-related costs among 25 to 59 year-old males in a 19-year individual follow-up. Eur J Public Health. 2002, 12 (2): 145-151. 10.1093/eurpub/12.2.145.CrossRefPubMed Kiiskinen U, Vartiainen E, Puska P, Pekurinen M: Smoking-related costs among 25 to 59 year-old males in a 19-year individual follow-up. Eur J Public Health. 2002, 12 (2): 145-151. 10.1093/eurpub/12.2.145.CrossRefPubMed
16.
go back to reference Doll R, Peto R, Boreham J, Sutherland I: Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ. 2004, 328 (7455): 1519-10.1136/bmj.38142.554479.AE.CrossRefPubMedPubMedCentral Doll R, Peto R, Boreham J, Sutherland I: Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ. 2004, 328 (7455): 1519-10.1136/bmj.38142.554479.AE.CrossRefPubMedPubMedCentral
17.
go back to reference Hodgson TA: Cigarette smoking and lifetime medical expenditures. Milbank Quarterly. 1992, 70 (1): 81-125. 10.2307/3350086.CrossRefPubMed Hodgson TA: Cigarette smoking and lifetime medical expenditures. Milbank Quarterly. 1992, 70 (1): 81-125. 10.2307/3350086.CrossRefPubMed
18.
go back to reference Rasmussen SR, Prescott E, Sorensen TI, Sogaard J: The total lifetime costs of smoking. Eur J Public Health. 2004, 14 (1): 95-100. 10.1093/eurpub/14.1.95.CrossRefPubMed Rasmussen SR, Prescott E, Sorensen TI, Sogaard J: The total lifetime costs of smoking. Eur J Public Health. 2004, 14 (1): 95-100. 10.1093/eurpub/14.1.95.CrossRefPubMed
19.
go back to reference Rasmussen SR, Prescott E, Sorensen TI, Sogaard J: The total lifetime health cost savings of smoking cessation to society. Eur J Public Health. 2005, 15 (6): 601-606. 10.1093/eurpub/cki024.CrossRefPubMed Rasmussen SR, Prescott E, Sorensen TI, Sogaard J: The total lifetime health cost savings of smoking cessation to society. Eur J Public Health. 2005, 15 (6): 601-606. 10.1093/eurpub/cki024.CrossRefPubMed
20.
go back to reference Adams M, Effertz T: The cost of smoking for the healthcare system and society in Germany. Alkohol, Tobacco and Complications. 2010, Stuttgart: Thieme Verlag, 57-64. Adams M, Effertz T: The cost of smoking for the healthcare system and society in Germany. Alkohol, Tobacco and Complications. 2010, Stuttgart: Thieme Verlag, 57-64.
21.
go back to reference Neubauer S, Welte R, Beiche A, Koenig HH, Buesch K, Leidl R: Mortality, morbidity and costs attributable to smoking in Germany: update and a 10-year comparison. Tobacco Control. 2006, 15 (6): 464-471. 10.1136/tc.2006.016030.CrossRefPubMedPubMedCentral Neubauer S, Welte R, Beiche A, Koenig HH, Buesch K, Leidl R: Mortality, morbidity and costs attributable to smoking in Germany: update and a 10-year comparison. Tobacco Control. 2006, 15 (6): 464-471. 10.1136/tc.2006.016030.CrossRefPubMedPubMedCentral
22.
go back to reference Welte R, König H, Leidl R: The costs of health damage and productivity losses attributable to cigarette smoking in Germany. Eur J Public Health. 2000, 10 (1): 31-38. 10.1093/eurpub/10.1.31.CrossRef Welte R, König H, Leidl R: The costs of health damage and productivity losses attributable to cigarette smoking in Germany. Eur J Public Health. 2000, 10 (1): 31-38. 10.1093/eurpub/10.1.31.CrossRef
23.
go back to reference Ruff LK, Volmer T, Nowak D, Meyer A: The economic impact of smoking in Germany. Eur Respiratory J. 2000, 16 (3): 385-390. 10.1034/j.1399-3003.2000.016003385.x.CrossRef Ruff LK, Volmer T, Nowak D, Meyer A: The economic impact of smoking in Germany. Eur Respiratory J. 2000, 16 (3): 385-390. 10.1034/j.1399-3003.2000.016003385.x.CrossRef
24.
go back to reference Prenzler A, Mittendorf T, von der Schulenburg JM: [Modelling of the costs of productivity losses due to smoking in Germany for the year 2005]. Gesundheitswesen. 2007, 69 (11): 635-643. 10.1055/s-2007-992781.CrossRefPubMed Prenzler A, Mittendorf T, von der Schulenburg JM: [Modelling of the costs of productivity losses due to smoking in Germany for the year 2005]. Gesundheitswesen. 2007, 69 (11): 635-643. 10.1055/s-2007-992781.CrossRefPubMed
25.
go back to reference Wegner C, Gutsch A, Hessel F, Wasem J: Smoking-attributable productivity loss in Germany - a partial sickness cost study based on the human capital potential method. Gesundheitswesen. 2004, 66 (7): 423-432. 10.1055/s-2004-813326.CrossRefPubMed Wegner C, Gutsch A, Hessel F, Wasem J: Smoking-attributable productivity loss in Germany - a partial sickness cost study based on the human capital potential method. Gesundheitswesen. 2004, 66 (7): 423-432. 10.1055/s-2004-813326.CrossRefPubMed
26.
go back to reference Wegner C, Gutsch A, Hessel F, Wasem J: Economic productivity losses as a result of smoking - an analysis under consideration of the friction cost method. Gesundh ökon Qual manag. 2005, 10 (6): 356-364. 10.1055/s-2005-858150.CrossRef Wegner C, Gutsch A, Hessel F, Wasem J: Economic productivity losses as a result of smoking - an analysis under consideration of the friction cost method. Gesundh ökon Qual manag. 2005, 10 (6): 356-364. 10.1055/s-2005-858150.CrossRef
27.
go back to reference World Health Organization: Economics of Tobacco Toolkit - Assessment of the Economic Costs of Smoking. 2011, Geneva: World Health Organization World Health Organization: Economics of Tobacco Toolkit - Assessment of the Economic Costs of Smoking. 2011, Geneva: World Health Organization
28.
go back to reference Holle R, Happich M, Lowel H, Wichmann HE: KORA–a research platform for population based health research. Gesundheitswesen. 2005, 67 (Suppl 1): S19-S25.CrossRefPubMed Holle R, Happich M, Lowel H, Wichmann HE: KORA–a research platform for population based health research. Gesundheitswesen. 2005, 67 (Suppl 1): S19-S25.CrossRefPubMed
29.
go back to reference Rathmann W, Haastert B, Icks A, Lowel H, Meisinger C, Holle R, Giani G: High prevalence of undiagnosed diabetes mellitus in Southern Germany: target populations for efficient screening. The KORA survey 2000. Diabetologia. 2003, 46 (2): 182-189.PubMed Rathmann W, Haastert B, Icks A, Lowel H, Meisinger C, Holle R, Giani G: High prevalence of undiagnosed diabetes mellitus in Southern Germany: target populations for efficient screening. The KORA survey 2000. Diabetologia. 2003, 46 (2): 182-189.PubMed
30.
go back to reference World Health Organization: Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors. 2004, Geneva: World Health Organization World Health Organization: Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors. 2004, Geneva: World Health Organization
31.
go back to reference Menn P, Heinrich J, Huber RM, Jorres RA, John J, Karrasch S, Peters A, Schulz H, Holle R: Direct medical costs of COPD - An excess cost approach based on two population-based studies. Respir Med. 2012, 106 (4): 540-548. 10.1016/j.rmed.2011.10.013.CrossRefPubMed Menn P, Heinrich J, Huber RM, Jorres RA, John J, Karrasch S, Peters A, Schulz H, Holle R: Direct medical costs of COPD - An excess cost approach based on two population-based studies. Respir Med. 2012, 106 (4): 540-548. 10.1016/j.rmed.2011.10.013.CrossRefPubMed
32.
go back to reference Krauth C, Hessel F, Hansmeier T, Wasem J, Seitz R, Schweikert B: Empirical standard costs for health economic evaluation in Germany - a proposal by the working group methods in health economic evaluation. Gesundheitswesen. 2005, 67 (10): 736-746. 10.1055/s-2005-858698.CrossRefPubMed Krauth C, Hessel F, Hansmeier T, Wasem J, Seitz R, Schweikert B: Empirical standard costs for health economic evaluation in Germany - a proposal by the working group methods in health economic evaluation. Gesundheitswesen. 2005, 67 (10): 736-746. 10.1055/s-2005-858698.CrossRefPubMed
35.
go back to reference Federal Statistical Office: Statistical Yearbook 2008 for the Federal Republic of Germany. 2009, Wiesbaden: Federal Statistical Office Federal Statistical Office: Statistical Yearbook 2008 for the Federal Republic of Germany. 2009, Wiesbaden: Federal Statistical Office
36.
go back to reference German Pension Fund: Statistics on Rehabilitation in 2008. 2009, Berlin: German Pension Fund German Pension Fund: Statistics on Rehabilitation in 2008. 2009, Berlin: German Pension Fund
38.
go back to reference Graf Von Der Schulenburg JM, Greiner W, Jost F, Klusen N, Kubin M, Leidl R, Mittendorf T, Rebscher H, Schoeffski O, Vauth C, et al: German recommendations on health economic evaluation: third and updated version of the Hanover Consensus. Value Health. 2008, 11 (4): 539-544. 10.1111/j.1524-4733.2007.00301.x.CrossRefPubMed Graf Von Der Schulenburg JM, Greiner W, Jost F, Klusen N, Kubin M, Leidl R, Mittendorf T, Rebscher H, Schoeffski O, Vauth C, et al: German recommendations on health economic evaluation: third and updated version of the Hanover Consensus. Value Health. 2008, 11 (4): 539-544. 10.1111/j.1524-4733.2007.00301.x.CrossRefPubMed
39.
go back to reference Koopmanschap MA, Rutten FFH, van Ineveld BM, van Roijen L: The friction cost method for measuring indirect costs of disease. J Health Econ. 1995, 14 (2): 171-189. 10.1016/0167-6296(94)00044-5.CrossRefPubMed Koopmanschap MA, Rutten FFH, van Ineveld BM, van Roijen L: The friction cost method for measuring indirect costs of disease. J Health Econ. 1995, 14 (2): 171-189. 10.1016/0167-6296(94)00044-5.CrossRefPubMed
40.
go back to reference Federal Statistical Office: National Accounts - Compensation per Employee, Gross Wages and Salaries. 2011, Wiesbaden: Federal Statistical Office Federal Statistical Office: National Accounts - Compensation per Employee, Gross Wages and Salaries. 2011, Wiesbaden: Federal Statistical Office
41.
go back to reference Barber J, Thompson S: Multiple regression of cost data: use of generalised linear models. J Health Serv Res Policy. 2004, 9 (4): 197-204. 10.1258/1355819042250249.CrossRefPubMed Barber J, Thompson S: Multiple regression of cost data: use of generalised linear models. J Health Serv Res Policy. 2004, 9 (4): 197-204. 10.1258/1355819042250249.CrossRefPubMed
42.
go back to reference Diehr P, Yanez D, Ash A, Hornbrook M, Lin DY: Methods for analyzing health care utilization and costs. Ann Rev Public Health. 1999, 20: 125-144. 10.1146/annurev.publhealth.20.1.125.CrossRef Diehr P, Yanez D, Ash A, Hornbrook M, Lin DY: Methods for analyzing health care utilization and costs. Ann Rev Public Health. 1999, 20: 125-144. 10.1146/annurev.publhealth.20.1.125.CrossRef
43.
go back to reference Izumi Y, Tsuji I, Ohkubo T, Kuwahara A, Nishino Y, Hisamichi S: Impact of smoking habit on medical care use and its costs: a prospective observation of National Health Insurance beneficiaries in Japan. Int J Epidemiol. 2001, 30 (3): 616-621. 10.1093/ije/30.3.616.CrossRefPubMed Izumi Y, Tsuji I, Ohkubo T, Kuwahara A, Nishino Y, Hisamichi S: Impact of smoking habit on medical care use and its costs: a prospective observation of National Health Insurance beneficiaries in Japan. Int J Epidemiol. 2001, 30 (3): 616-621. 10.1093/ije/30.3.616.CrossRefPubMed
44.
go back to reference Jorm L, Shepherd L, Rogers K, Blyth F: Smoking and use of primary care services: findings from a population-based cohort study linked with administrative claims data. BMC Health Servi Res. 2012, 12 (1): 263-10.1186/1472-6963-12-263.CrossRef Jorm L, Shepherd L, Rogers K, Blyth F: Smoking and use of primary care services: findings from a population-based cohort study linked with administrative claims data. BMC Health Servi Res. 2012, 12 (1): 263-10.1186/1472-6963-12-263.CrossRef
45.
go back to reference Fishman PA, Thompson EE, Merikle E, Curry SJ: Changes in health care costs before and after smoking cessation. Nicotine Tob Res. 2006, 8 (3): 393-401. 10.1080/14622200600670314.CrossRefPubMed Fishman PA, Thompson EE, Merikle E, Curry SJ: Changes in health care costs before and after smoking cessation. Nicotine Tob Res. 2006, 8 (3): 393-401. 10.1080/14622200600670314.CrossRefPubMed
46.
go back to reference Seidl H, Meisinger C, Wende R, Holle R: Empirical analysis shows reduced cost data collection may be an efficient method in economic clinical trials. BMC Health Serv Res. 2012, 12 (1): 318-10.1186/1472-6963-12-318.CrossRefPubMedPubMedCentral Seidl H, Meisinger C, Wende R, Holle R: Empirical analysis shows reduced cost data collection may be an efficient method in economic clinical trials. BMC Health Serv Res. 2012, 12 (1): 318-10.1186/1472-6963-12-318.CrossRefPubMedPubMedCentral
47.
go back to reference Evans C, Crawford B: Patient self-reports in pharmacoeconomic studies. Their use and impact on study validity. Pharmacoeconomics. 1999, 15 (3): 241-256. 10.2165/00019053-199915030-00004.CrossRefPubMed Evans C, Crawford B: Patient self-reports in pharmacoeconomic studies. Their use and impact on study validity. Pharmacoeconomics. 1999, 15 (3): 241-256. 10.2165/00019053-199915030-00004.CrossRefPubMed
48.
go back to reference Holle R, Hochadel M, Reitmeir P, Meisinger C, Wichmann HE: Prolonged recruitment efforts in health surveys: effects on response, costs, and potential bias. Epidemiol. 2006, 17 (6): 639-643. 10.1097/01.ede.0000239731.86975.7f.CrossRef Holle R, Hochadel M, Reitmeir P, Meisinger C, Wichmann HE: Prolonged recruitment efforts in health surveys: effects on response, costs, and potential bias. Epidemiol. 2006, 17 (6): 639-643. 10.1097/01.ede.0000239731.86975.7f.CrossRef
49.
go back to reference WHO Collaborating Centre for Drug Statistics Methodology: Guidelines for ATC classification and DDD assignment 2010. 2009, Oslo: World Health Organization WHO Collaborating Centre for Drug Statistics Methodology: Guidelines for ATC classification and DDD assignment 2010. 2009, Oslo: World Health Organization
51.
go back to reference World Health Organization: WHO Framework Convention on Tobacco Control. 2003, Geneva: World Health Organization World Health Organization: WHO Framework Convention on Tobacco Control. 2003, Geneva: World Health Organization
Metadata
Title
The association of smoking status with healthcare utilisation, productivity loss and resulting costs: results from the population-based KORA F4 study
Authors
Margarethe Wacker
Rolf Holle
Joachim Heinrich
Karl-Heinz Ladwig
Annette Peters
Reiner Leidl
Petra Menn
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2013
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-13-278

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