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Published in: European Review of Aging and Physical Activity 1/2015

Open Access 01-12-2015 | Review article

The application of strength and power related field tests in older adults: criteria, current status and a future perspective

Authors: G. Ruben H. Regterschot, Tobias Morat, Marjanne Folkersma, Wiebren Zijlstra

Published in: European Review of Aging and Physical Activity | Issue 1/2015

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Abstract

Leg muscle strength (LMS) and leg muscle power (LMP) are determinants of aspects of functional status and important parameters for measuring intervention effects in older adults. Field tests are often used for the evaluation of LMS and LMP in older persons. However, criteria important for the application of strength and power related field tests in older adults have not been systematically taken into account and are not yet fully listed and described in a single publication. Therefore, this paper describes criteria important for the application of strength and power related field tests in older adults. In addition, strength and power related field tests commonly used in older adults are evaluated by using the described criteria. Based on this evaluation, this paper provides a perspective on the further development of field tests. Criteria important for strength and power related field tests are: adequate accuracy, precision, concurrent validity, clinical validity, practical feasibility and pure strength or power outcomes. Commonly used strength and power related field tests do not meet all the aforementioned criteria. Therefore, further development of field tests is necessary. Mobile sensing systems are potentially useful for the evaluation of LMS and LMP in older adults. Mobile sensing systems do not have the limitations of commonly used field tests and provide important additional advantages. In particular, mobile sensing systems offer the opportunity of continuous monitoring during free-movement in the home-environment, thereby reducing the need of standardized assessments by health-care professionals. Future studies should examine the clinical validity of mobile sensing systems and evaluate the application of sensor technology in exercise-based interventions.
Literature
1.
go back to reference Bean JF, Kiely DK, Herman S, Leveille SG, Mizer K, Frontera WR, et al. The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc. 2002;50:461–7.CrossRefPubMed Bean JF, Kiely DK, Herman S, Leveille SG, Mizer K, Frontera WR, et al. The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc. 2002;50:461–7.CrossRefPubMed
2.
go back to reference Bean JF, Leveille SG, Kiely DK, Bandinelli S, Guralnik JM, Ferrucci L. A comparison of leg power and leg strength within the InCHIANTI study: which influences mobility more? J Gerontol A Biol Sci Med Sci. 2003;58:728–33.CrossRefPubMed Bean JF, Leveille SG, Kiely DK, Bandinelli S, Guralnik JM, Ferrucci L. A comparison of leg power and leg strength within the InCHIANTI study: which influences mobility more? J Gerontol A Biol Sci Med Sci. 2003;58:728–33.CrossRefPubMed
3.
go back to reference Foldvari M, Clark M, Laviolette LC, Bernstein MA, Kaliton D, Castaneda C, et al. Association of muscle power with functional status in community-dwelling elderly women. J Gerontol A Biol Sci Med Sci. 2000;55:M192–9.CrossRefPubMed Foldvari M, Clark M, Laviolette LC, Bernstein MA, Kaliton D, Castaneda C, et al. Association of muscle power with functional status in community-dwelling elderly women. J Gerontol A Biol Sci Med Sci. 2000;55:M192–9.CrossRefPubMed
4.
go back to reference Horlings CG, van Engelen BG, Allum JH, Bloem BR. A weak balance: the contribution of muscle weakness to postural instability and falls. Nat Clin Pract Neurol. 2008;4:504–15.CrossRefPubMed Horlings CG, van Engelen BG, Allum JH, Bloem BR. A weak balance: the contribution of muscle weakness to postural instability and falls. Nat Clin Pract Neurol. 2008;4:504–15.CrossRefPubMed
5.
go back to reference Perry MC, Carville SF, Smith IC, Rutherford OM, Newham DJ. Strength, power output and symmetry of leg muscles: effect of age and history of falling. Eur J Appl Physiol. 2007;100:553–61.CrossRefPubMed Perry MC, Carville SF, Smith IC, Rutherford OM, Newham DJ. Strength, power output and symmetry of leg muscles: effect of age and history of falling. Eur J Appl Physiol. 2007;100:553–61.CrossRefPubMed
6.
7.
go back to reference Skelton DA, Greig CA, Davies JM, Young A. Strength, power and related functional ability of healthy people aged 65-89 years. Age Ageing. 1994;23:371–7.CrossRefPubMed Skelton DA, Greig CA, Davies JM, Young A. Strength, power and related functional ability of healthy people aged 65-89 years. Age Ageing. 1994;23:371–7.CrossRefPubMed
8.
go back to reference Suzuki T, Bean JF, Fielding RA. Muscle power of the ankle flexors predicts functional performance in community-dwelling older women. J Am Geriatr Soc. 2001;49:1161–7.CrossRefPubMed Suzuki T, Bean JF, Fielding RA. Muscle power of the ankle flexors predicts functional performance in community-dwelling older women. J Am Geriatr Soc. 2001;49:1161–7.CrossRefPubMed
9.
go back to reference Stark T, Walker B, Phillips JK, Fejer R, Beck R. Hand-held dynamometry correlation with the gold standard isokinetic dynamometry: a systematic review. PM R. 2011;3:472–9.CrossRefPubMed Stark T, Walker B, Phillips JK, Fejer R, Beck R. Hand-held dynamometry correlation with the gold standard isokinetic dynamometry: a systematic review. PM R. 2011;3:472–9.CrossRefPubMed
10.
go back to reference Whitney SL, Wrisley DM, Marchetti GF, Gee MA, Redfern MS, Furman JM. Clinical measurement of sit-to-stand performance in people with balance disorders: validity of data for the Five-Times-Sit-to-Stand Test. Phys Ther. 2005;85:1034–45.PubMed Whitney SL, Wrisley DM, Marchetti GF, Gee MA, Redfern MS, Furman JM. Clinical measurement of sit-to-stand performance in people with balance disorders: validity of data for the Five-Times-Sit-to-Stand Test. Phys Ther. 2005;85:1034–45.PubMed
11.
go back to reference Bean JF, Kiely DK, LaRose S, Alian J, Frontera WR. Is stair climb power a clinically relevant measure of leg power impairments in at-risk older adults? Arch Phys Med Rehabil. 2007;88:604–9.CrossRefPubMed Bean JF, Kiely DK, LaRose S, Alian J, Frontera WR. Is stair climb power a clinically relevant measure of leg power impairments in at-risk older adults? Arch Phys Med Rehabil. 2007;88:604–9.CrossRefPubMed
12.
go back to reference Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49:M85–94.CrossRefPubMed Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49:M85–94.CrossRefPubMed
13.
go back to reference Moe-Nilssen R, Nordin E, Lundin-Olsson L, Work Package 3 of European Community Research Network Prevention of Falls Network Europe. Criteria for evaluation of measurement properties of clinical balance measures for use in fall prevention studies. J Eval Clin Pract. 2008;14:236–40.CrossRefPubMed Moe-Nilssen R, Nordin E, Lundin-Olsson L, Work Package 3 of European Community Research Network Prevention of Falls Network Europe. Criteria for evaluation of measurement properties of clinical balance measures for use in fall prevention studies. J Eval Clin Pract. 2008;14:236–40.CrossRefPubMed
14.
go back to reference Powers SK, Howley ET. Exercise physiology: theory and application to fitness and performance. New York: McGraw-Hill; 2004. Powers SK, Howley ET. Exercise physiology: theory and application to fitness and performance. New York: McGraw-Hill; 2004.
15.
go back to reference Malmberg JJ, Miilunpalo SI, Vuori IM, Pasanen ME, Oja P, Haapanen-Niemi NA. A health-related fitness and functional performance test battery for middle-aged and older adults: feasibility and health-related content validity. Arch Phys Med Rehabil. 2002;83:666–77.CrossRefPubMed Malmberg JJ, Miilunpalo SI, Vuori IM, Pasanen ME, Oja P, Haapanen-Niemi NA. A health-related fitness and functional performance test battery for middle-aged and older adults: feasibility and health-related content validity. Arch Phys Med Rehabil. 2002;83:666–77.CrossRefPubMed
16.
go back to reference Working Group 2 of the Joint Committee for Guides in Metrology (JCGM/WG 2). International vocabulary of metrology — Basic and general concepts and associated terms (VIM). 2008. http://www.bipm.org. Working Group 2 of the Joint Committee for Guides in Metrology (JCGM/WG 2). International vocabulary of metrology — Basic and general concepts and associated terms (VIM). 2008. http://​www.​bipm.​org.
17.
go back to reference Pryseley A, Mintiens K, Knapen K, Van der Stede Y, Molenberghs G. Estimating precision, repeatability, and reproducibility from Gaussian and non- Gaussian data: a mixed models approach. J Appl Stat. 2010;37:1729–47.CrossRef Pryseley A, Mintiens K, Knapen K, Van der Stede Y, Molenberghs G. Estimating precision, repeatability, and reproducibility from Gaussian and non- Gaussian data: a mixed models approach. J Appl Stat. 2010;37:1729–47.CrossRef
18.
go back to reference Weir JP. Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. J Strength Cond Res. 2005;19:231–40.PubMed Weir JP. Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. J Strength Cond Res. 2005;19:231–40.PubMed
19.
go back to reference Bruton A, Conway JH, Holgate ST. Reliability: What is it and how is it measured? Physiotherapy. 2000;86:94–9.CrossRef Bruton A, Conway JH, Holgate ST. Reliability: What is it and how is it measured? Physiotherapy. 2000;86:94–9.CrossRef
20.
go back to reference Rankin G, Stokes M. Reliability of assessment tools in rehabilitation: an illustration of appropriate statistical analyses. Clin Rehabil. 1998;12:187–99.CrossRefPubMed Rankin G, Stokes M. Reliability of assessment tools in rehabilitation: an illustration of appropriate statistical analyses. Clin Rehabil. 1998;12:187–99.CrossRefPubMed
21.
go back to reference Fleiss JL. The Design and Analysis of Clinical Experiments. New York: John Wiley; 1986. Fleiss JL. The Design and Analysis of Clinical Experiments. New York: John Wiley; 1986.
22.
go back to reference Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307–10.CrossRefPubMed Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307–10.CrossRefPubMed
23.
go back to reference Gouttebarge V, Wind H, Kuijer PP, Frings-Dresen MH. Reliability and validity of Functional Capacity Evaluation methods: a systematic review with reference to Blankenship system, Ergos work simulator, Ergo-Kit and Isernhagen work system. Int Arch Occup Environ Health. 2004;77:527–37.CrossRefPubMed Gouttebarge V, Wind H, Kuijer PP, Frings-Dresen MH. Reliability and validity of Functional Capacity Evaluation methods: a systematic review with reference to Blankenship system, Ergos work simulator, Ergo-Kit and Isernhagen work system. Int Arch Occup Environ Health. 2004;77:527–37.CrossRefPubMed
24.
go back to reference Taylor JD, Fletcher JP. Correlation between the 8-repetition maximum test and isokinetic dynamometry in the measurement of muscle strength of the knee extensors: A concurrent validity study. Physiother Theory Pract. 2013;29:335–41.CrossRefPubMed Taylor JD, Fletcher JP. Correlation between the 8-repetition maximum test and isokinetic dynamometry in the measurement of muscle strength of the knee extensors: A concurrent validity study. Physiother Theory Pract. 2013;29:335–41.CrossRefPubMed
25.
go back to reference Campanini I, Merlo A. Reliability, smallest real difference and concurrent validity of indices computed from GRF components in gait of stroke patients. Gait Posture. 2009;30:127–31.CrossRefPubMed Campanini I, Merlo A. Reliability, smallest real difference and concurrent validity of indices computed from GRF components in gait of stroke patients. Gait Posture. 2009;30:127–31.CrossRefPubMed
26.
go back to reference Domholdt E. Physical Therapy Research: Principles and Applications. Philadelphia, PA: Saunders; 2000. Domholdt E. Physical Therapy Research: Principles and Applications. Philadelphia, PA: Saunders; 2000.
27.
go back to reference Greiner M, Pfeiffer D, Smith RD. Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med. 2000;45:23–41.CrossRefPubMed Greiner M, Pfeiffer D, Smith RD. Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med. 2000;45:23–41.CrossRefPubMed
28.
go back to reference Husted JA, Cook RJ, Farewell VT, Gladman DD. Methods for assessing responsiveness: a critical review and recommendations. J Clin Epidemiol. 2000;53:459–68.CrossRefPubMed Husted JA, Cook RJ, Farewell VT, Gladman DD. Methods for assessing responsiveness: a critical review and recommendations. J Clin Epidemiol. 2000;53:459–68.CrossRefPubMed
30.
go back to reference Mijnarends DM, Meijers JM, Halfens RJ, ter Borg S, Luiking YC, Verlaan S, et al. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review. J Am Med Dir Assoc. 2013;14:170–8.CrossRefPubMed Mijnarends DM, Meijers JM, Halfens RJ, ter Borg S, Luiking YC, Verlaan S, et al. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review. J Am Med Dir Assoc. 2013;14:170–8.CrossRefPubMed
31.
go back to reference Freiberger E, de Vreede P, Schoene D, Rydwik E, Mueller V, Frändin K, et al. Performance-based physical function in older community-dwelling persons: a systematic review of instruments. Age Ageing. 2012;41:712–21.CrossRefPubMed Freiberger E, de Vreede P, Schoene D, Rydwik E, Mueller V, Frändin K, et al. Performance-based physical function in older community-dwelling persons: a systematic review of instruments. Age Ageing. 2012;41:712–21.CrossRefPubMed
32.
go back to reference Rydwik E, Bergland A, Forsén L, Frändin K. Investigation into the reliability and validity of the measurement of elderly people's clinical walking speed: a systematic review. Physiother Theory Pract. 2012;28:238–56.CrossRefPubMed Rydwik E, Bergland A, Forsén L, Frändin K. Investigation into the reliability and validity of the measurement of elderly people's clinical walking speed: a systematic review. Physiother Theory Pract. 2012;28:238–56.CrossRefPubMed
33.
go back to reference Agre JC, Magness JL, Hull SZ, Wright KC, Baxter TL, Patterson R, et al. Strength testing with a portable dynamometer: reliability for upper and lower extremities. Arch Phys Med Rehabil. 1987;68:454–8.PubMed Agre JC, Magness JL, Hull SZ, Wright KC, Baxter TL, Patterson R, et al. Strength testing with a portable dynamometer: reliability for upper and lower extremities. Arch Phys Med Rehabil. 1987;68:454–8.PubMed
34.
go back to reference Verkerke GJ, Lemmink KA, Slagers AJ, Westhoff MH, van Riet GA, Rakhorst G. Precision, comfort and mechanical performance of the Quadriso-tester, a quadriceps force measuring device. Med Biol Eng Comput. 2003;41:283–9.CrossRefPubMed Verkerke GJ, Lemmink KA, Slagers AJ, Westhoff MH, van Riet GA, Rakhorst G. Precision, comfort and mechanical performance of the Quadriso-tester, a quadriceps force measuring device. Med Biol Eng Comput. 2003;41:283–9.CrossRefPubMed
35.
go back to reference Zijlstra W, Aminian K. Mobility assessment in older people, new possibilities and challenges. Eur J Ageing. 2007;4:3–12.CrossRef Zijlstra W, Aminian K. Mobility assessment in older people, new possibilities and challenges. Eur J Ageing. 2007;4:3–12.CrossRef
36.
go back to reference Zijlstra W, Becker C, Pfeiffer K. Wearable systems for monitoring mobility related activities: from technology to application for healthcare services. In: Ziefle M, Röcker C, editors. E-Health, Assistive Technologies and Applications for Assisted Living. Hershey PA: IGI Global; 2011. p. 244–67.CrossRef Zijlstra W, Becker C, Pfeiffer K. Wearable systems for monitoring mobility related activities: from technology to application for healthcare services. In: Ziefle M, Röcker C, editors. E-Health, Assistive Technologies and Applications for Assisted Living. Hershey PA: IGI Global; 2011. p. 244–67.CrossRef
37.
go back to reference Taylor MJ, McCormick D, Shawis T, Impson R, Griffin M. Activity-promoting gaming systems in exercise and rehabilitation. J Rehabil Res Dev. 2011;48:1171–86.CrossRefPubMed Taylor MJ, McCormick D, Shawis T, Impson R, Griffin M. Activity-promoting gaming systems in exercise and rehabilitation. J Rehabil Res Dev. 2011;48:1171–86.CrossRefPubMed
38.
go back to reference Regterschot GRH, Folkersma M, Zhang W, Baldus H, Stevens M, Zijlstra W. Sensitivity of sensor-based sit-to-stand peak power to the effects of training leg strength, leg power and balance in older adults. Gait Posture. 2014;39:303–7.CrossRefPubMed Regterschot GRH, Folkersma M, Zhang W, Baldus H, Stevens M, Zijlstra W. Sensitivity of sensor-based sit-to-stand peak power to the effects of training leg strength, leg power and balance in older adults. Gait Posture. 2014;39:303–7.CrossRefPubMed
39.
go back to reference Regterschot GRH, Zhang W, Baldus H, Stevens M, Zijlstra W. Test-retest reliability of sensor-based sit-to-stand measures in young and older adults. Gait Posture. 2014;40:220–4.CrossRefPubMed Regterschot GRH, Zhang W, Baldus H, Stevens M, Zijlstra W. Test-retest reliability of sensor-based sit-to-stand measures in young and older adults. Gait Posture. 2014;40:220–4.CrossRefPubMed
40.
go back to reference Zijlstra W, Bisseling RW, Schlumbohm S, Baldus H. A body-fixed-sensor-based analysis of power during sit-to-stand movements. Gait Posture. 2010;31:272–8.CrossRefPubMed Zijlstra W, Bisseling RW, Schlumbohm S, Baldus H. A body-fixed-sensor-based analysis of power during sit-to-stand movements. Gait Posture. 2010;31:272–8.CrossRefPubMed
41.
go back to reference Chen PY, Wei SH, Hsieh WL, Cheen JR, Chen LK, Kao CL. Lower limb power rehabilitation (LLPR) using interactive video game for improvement of balance function in older people. Arch Gerontol Geriatr. 2012;55:677–82.CrossRefPubMed Chen PY, Wei SH, Hsieh WL, Cheen JR, Chen LK, Kao CL. Lower limb power rehabilitation (LLPR) using interactive video game for improvement of balance function in older people. Arch Gerontol Geriatr. 2012;55:677–82.CrossRefPubMed
42.
go back to reference Cheng YY, Wei SH, Chen PY, Tsai MW, Cheng IC, Liu DH, et al. Can sit-to-stand lower limb muscle power predict fall status? Gait Posture. 2014;40:403–7.CrossRefPubMed Cheng YY, Wei SH, Chen PY, Tsai MW, Cheng IC, Liu DH, et al. Can sit-to-stand lower limb muscle power predict fall status? Gait Posture. 2014;40:403–7.CrossRefPubMed
43.
go back to reference Lindemann U, Muche R, Stuber M, Zijlstra W, Hauer K, Becker C. Coordination of strength exertion during the chair-rise movement in very old people. J Gerontol A Biol Sci Med Sci. 2007;62:636–40.CrossRefPubMed Lindemann U, Muche R, Stuber M, Zijlstra W, Hauer K, Becker C. Coordination of strength exertion during the chair-rise movement in very old people. J Gerontol A Biol Sci Med Sci. 2007;62:636–40.CrossRefPubMed
44.
go back to reference Zech A, Steib S, Sportwiss D, Freiberger E, Pfeifer K. Functional muscle power testing in young, middle-aged, and community-dwelling nonfrail and prefrail older adults. Arch Phys Med Rehabil. 2011;92:967–71.CrossRefPubMed Zech A, Steib S, Sportwiss D, Freiberger E, Pfeifer K. Functional muscle power testing in young, middle-aged, and community-dwelling nonfrail and prefrail older adults. Arch Phys Med Rehabil. 2011;92:967–71.CrossRefPubMed
45.
go back to reference Nadler SF, DePrince ML, Hauesien N, Malanga GA, Stitik TP, Price E. Portable dynamometer anchoring station for measuring strength of the hip extensors and abductors. Arch Phys Med Rehabil. 2000;81:1072–6.CrossRefPubMed Nadler SF, DePrince ML, Hauesien N, Malanga GA, Stitik TP, Price E. Portable dynamometer anchoring station for measuring strength of the hip extensors and abductors. Arch Phys Med Rehabil. 2000;81:1072–6.CrossRefPubMed
46.
go back to reference Zhang W, Regterschot GRH, Schaabova H, Baldus H, Zijlstra W. Test-retest reliability of a pendant-worn sensor device in measuring chair rise performance in older persons. Sensors (Basel). 2014;14:8705–17.CrossRef Zhang W, Regterschot GRH, Schaabova H, Baldus H, Zijlstra W. Test-retest reliability of a pendant-worn sensor device in measuring chair rise performance in older persons. Sensors (Basel). 2014;14:8705–17.CrossRef
47.
go back to reference Van Acht V, Bongers E, Lambert N, Verberne R. Miniature wireless inertial sensor for measuring human motions. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:6279–82.PubMed Van Acht V, Bongers E, Lambert N, Verberne R. Miniature wireless inertial sensor for measuring human motions. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:6279–82.PubMed
48.
go back to reference Geraedts HA, Zijlstra W, Zhang W, Bulstra S, Stevens M. Adherence to and effectiveness of an individually tailored home-based exercise program for frail older adults, driven by mobility monitoring: design of a prospective cohort study. BMC Public Health. 2014;14:570.PubMedCentralCrossRefPubMed Geraedts HA, Zijlstra W, Zhang W, Bulstra S, Stevens M. Adherence to and effectiveness of an individually tailored home-based exercise program for frail older adults, driven by mobility monitoring: design of a prospective cohort study. BMC Public Health. 2014;14:570.PubMedCentralCrossRefPubMed
49.
go back to reference de Bruin ED, Hartmann A, Uebelhart D, Murer K, Zijlstra W. Wearable systems for monitoring mobility-related activities in older people: a systematic review. Clin Rehabil. 2008;22:878–95.CrossRefPubMed de Bruin ED, Hartmann A, Uebelhart D, Murer K, Zijlstra W. Wearable systems for monitoring mobility-related activities in older people: a systematic review. Clin Rehabil. 2008;22:878–95.CrossRefPubMed
Metadata
Title
The application of strength and power related field tests in older adults: criteria, current status and a future perspective
Authors
G. Ruben H. Regterschot
Tobias Morat
Marjanne Folkersma
Wiebren Zijlstra
Publication date
01-12-2015
Publisher
BioMed Central
Published in
European Review of Aging and Physical Activity / Issue 1/2015
Print ISSN: 1813-7253
Electronic ISSN: 1861-6909
DOI
https://doi.org/10.1186/s11556-015-0147-6

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