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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 4/2020

01-10-2020 | Thalassemia | Images

Pseudo-Thrombocytosis Caused by Extreme Microcytosis in a Patient with Alpha Thalassemia Trait

Authors: Alexander A. Slota, Devin Malik, Diane Hall

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 4/2020

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Excerpt

While automated blood counts have revolutionized laboratory medicine and hematology, there are instances in which visualization of a peripheral blood smear is superior to instrument values. We describe a 57-year-old African American male with alpha thalassemia trait with spurious thrombocytosis. While thrombocytopenia can be a complication of hypersplenism in thalassemia [1], thrombocytosis is rare in alpha thalassemia trait [2]. Our patient’s baseline platelet count was 250 × 109/L. However, laboratory results noted transiently elevated platelet counts routinely between 1200 × 109/L and 2000 × 109/L. He also had anemia (hemoglobin 85 g/L) and microcytosis (MCV 56.9 fl). …
Literature
1.
Vichinsky E (2010) Complexity of alpha thalassemia: growing health problem with new approaches to screening, diagnosis, and therapy. Ann N Y Acad Sci 1202:180–187CrossRef
2.
Taylor S, Strauch S, Lewis S (2015) Thrombocytosis in a patient with alpha thalassemia trait. Lab Med 46:e7–e12CrossRef
Metadata
Title
Pseudo-Thrombocytosis Caused by Extreme Microcytosis in a Patient with Alpha Thalassemia Trait
Authors
Alexander A. Slota
Devin Malik
Diane Hall
Publication date
01-10-2020
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue 4/2020
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-020-01297-6

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