Published in:
01-11-2003 | Brief Report
Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia
Authors:
G. Christopher Wood, Scott D. Hanes, Bradley A. Boucher, Martin A. Croce, Timothy C. Fabian
Published in:
Intensive Care Medicine
|
Issue 11/2003
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Abstract
Objective
To report the use of tetracyclines for the treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP).
Design
Observational case series.
Setting
The Presley Regional Trauma Center located within the Regional Medical Center, Memphis, Tennessee, USA.
Patients and participants
Seven critically ill trauma patients with VAP caused by A. baumannii isolates that were resistant to all antibiotics tested except for doxycycline or minocycline.
Interventions
Patients were treated with IV doxycycline or minocycline for an average of 13.5 (range 9–20) days.
Measurements and results
Doxycycline or minocycline was successful in six of seven patients.
Conclusions
Doxycycline or minocycline may be effective for treating multidrug-resistant A. baumannii VAP.