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Published in: Intensive Care Medicine 11/2003

01-11-2003 | Brief Report

Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia

Authors: G. Christopher Wood, Scott D. Hanes, Bradley A. Boucher, Martin A. Croce, Timothy C. Fabian

Published in: Intensive Care Medicine | Issue 11/2003

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Abstract

Objective

To report the use of tetracyclines for the treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP).

Design

Observational case series.

Setting

The Presley Regional Trauma Center located within the Regional Medical Center, Memphis, Tennessee, USA.

Patients and participants

Seven critically ill trauma patients with VAP caused by A. baumannii isolates that were resistant to all antibiotics tested except for doxycycline or minocycline.

Interventions

Patients were treated with IV doxycycline or minocycline for an average of 13.5 (range 9–20) days.

Measurements and results

Doxycycline or minocycline was successful in six of seven patients.

Conclusions

Doxycycline or minocycline may be effective for treating multidrug-resistant A. baumannii VAP.
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Metadata
Title
Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia
Authors
G. Christopher Wood
Scott D. Hanes
Bradley A. Boucher
Martin A. Croce
Timothy C. Fabian
Publication date
01-11-2003
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 11/2003
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-003-1811-2

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