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Forensic Science, Medicine and Pathology

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Open Access 01-06-2014 | Letter to the Editor

Testing for antiphospholipid antibodies at autopsy

Authors: Bartosz Hudzik, Janusz Szkodzinski, Lech Polonski

Published in: Forensic Science, Medicine and Pathology | Issue 2/2014

Excerpt

Certain issues require further consideration when testing for antiphospholipid antibodies (APLAs), particularly, when the tests are to be carried out during autopsy [1‐3]. First and foremost, laboratory tests must be positive on at least two different occasions, at least 12 weeks apart [4]. We have to keep in mind that APLAs may appear (transiently or persistently) in a wide variety of clinical conditions and even in healthy individuals [5]. Testing for APLAs on only one occasion may lead to false conclusions [1]. Positive results often cause unjustified concern and, conversely, a negative test may provide false reassurance [2]. …

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Title: Testing for antiphospholipid antibodies at autopsy
Authors: Bartosz Hudzik
Janusz Szkodzinski
Lech Polonski
Publication date: 01-06-2014
Publisher: Springer US
Published in: Forensic Science, Medicine and Pathology / Issue 2/2014
Print ISSN: 1547-769X
Electronic ISSN: 1556-2891
DOI: https://doi.org/10.1007/s12024-014-9528-9

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