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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-11-2019 | Telemedicine | Pediatrics

Smartphone-based fundus photography for screening of plus-disease retinopathy of prematurity

Authors: Tapan P. Patel, Michael T. Aaberg, Yannis M. Paulus, Philip Lieu, Vaidehi S. Dedania, Cynthia X. Qian, Cagri G. Besirli, Todd Margolis, Daniel A. Fletcher, Tyson N. Kim

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 11/2019

Abstract

Background

Inadequate screening of treatment-warranted retinopathy of prematurity (ROP) can lead to devastating visual outcomes. Especially in resource-poor communities, the use of an affordable, portable, and easy to use smartphone-based non-contact fundus photography device may prove useful for screening for high-risk ROP. This study evaluates the feasibility of screening for high-risk ROP using a novel smartphone-based fundus photography device, RetinaScope.

Methods

Retinal images were obtained using RetinaScope on a cohort of prematurely born infants during routine examinations for ROP. Images were reviewed by two masked graders who determined the image quality, the presence or absence of plus disease, and whether there was retinopathy that met predefined criteria for referral. The agreement between image-based assessments was compared to the gold standard indirect ophthalmoscopic assessment.

Results

Fifty-four eyes of 27 infants were included. A wide-field fundus photograph was obtained using RetinaScope. Image quality was acceptable or excellent in 98% and 95% of cases. There was substantial agreement between the gold standard and photographic assessment of presence or absence of plus disease (Cohen’s κ = 0.85). Intergrader agreement on the presence of any retinopathy in photographs was also high (κ = 0.92).

Conclusions

RetinaScope can capture digital retinal photographs of prematurely born infants with good image quality for grading of plus disease.

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Title: Smartphone-based fundus photography for screening of plus-disease retinopathy of prematurity
Authors: Tapan P. Patel
Michael T. Aaberg
Yannis M. Paulus
Philip Lieu
Vaidehi S. Dedania
Cynthia X. Qian
Cagri G. Besirli
Todd Margolis
Daniel A. Fletcher
Tyson N. Kim
Publication date: 01-11-2019
Publisher: Springer Berlin Heidelberg
Keyword: Telemedicine
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 11/2019
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-019-04470-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Smartphone-based fundus photography for screening of plus-disease retinopathy of prematurity

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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