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Published in: Child's Nervous System 8/2018

Open Access 01-08-2018 | Technical Note

Technical report: 3D printing of the brain for use as a visual-aid tool to communicate MR imaging features of hypoxic ischaemic injury at term with non-physicians

Authors: Savvas Andronikou, Ewan Simpson, Maciej Klemm, Schadie Vedajallam, Anith Chacko, Ngoc Jade Thai

Published in: Child's Nervous System | Issue 8/2018

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Abstract

3D printing has been used in several medical applications. There are no reports however of 3D printing of the brain in children for demonstrating pathology to non-medical professionals such as lawyers. We printed 3D models of the paediatric brain from volumetric MRI in cases of severe and moderate hypoxic ischaemic injury as well as a normal age matched control, as follows: MRI DICOM data was converted to NifTI (Neuroimaging Informatics Technology Initiative) format; segmentation of the brain into CSF, grey, and white matter was performed; the segmented data was converted to STL format and printed on a commercially available scanner. The characteristic volume loss and surface features of hypoxic ischaemic injury are visible in these models, which could be of value in the communication of the nature and severity of such an insult in a court setting as they can be handled and viewed from up close.
Literature
1.
go back to reference Rengier F, Mehndiratta A, von Tengg-Kobligk H, Zechmann CM, Unterhinninghofen R, Kauczor HU, Giesel FL (2010) 3D printing based on imaging data: review of medical applications. Int J Comput Assist Radiol Surg 5:335–341CrossRefPubMed Rengier F, Mehndiratta A, von Tengg-Kobligk H, Zechmann CM, Unterhinninghofen R, Kauczor HU, Giesel FL (2010) 3D printing based on imaging data: review of medical applications. Int J Comput Assist Radiol Surg 5:335–341CrossRefPubMed
3.
go back to reference Nikas I, Dermentzoglou V, Theofanopoulou M, Theodoropoulos V (2008) Parasagittal lesions and ulegyria in hypoxic-ischemic encephalopathy: neuroimaging findings and review of the pathogenesis. J Child Neurol 23:51–58CrossRefPubMed Nikas I, Dermentzoglou V, Theofanopoulou M, Theodoropoulos V (2008) Parasagittal lesions and ulegyria in hypoxic-ischemic encephalopathy: neuroimaging findings and review of the pathogenesis. J Child Neurol 23:51–58CrossRefPubMed
4.
go back to reference Kurth F, Luders E, Gaser C (2015) Voxel-based morphometry. In: Toga A (ed) Brain mapping: an encyclopedic reference. Academic Press, Cambridge, pp 345–349CrossRef Kurth F, Luders E, Gaser C (2015) Voxel-based morphometry. In: Toga A (ed) Brain mapping: an encyclopedic reference. Academic Press, Cambridge, pp 345–349CrossRef
5.
go back to reference Azzopardi D, Strohm B, Edwards AD, Halliday H, Juszczak E, Levene M, Thoresen M, Whitelaw A, Brocklehurst P, on behalf of the Steering Group and TOBY Cooling Register participants (2009) Treatment of asphyxiated newborns with moderate hypothermia in routine clinical practice: how cooling is managed in the UK outside a clinical trial. Arch Dis Child Fetal Neonatal Ed 94:F260–F264CrossRefPubMed Azzopardi D, Strohm B, Edwards AD, Halliday H, Juszczak E, Levene M, Thoresen M, Whitelaw A, Brocklehurst P, on behalf of the Steering Group and TOBY Cooling Register participants (2009) Treatment of asphyxiated newborns with moderate hypothermia in routine clinical practice: how cooling is managed in the UK outside a clinical trial. Arch Dis Child Fetal Neonatal Ed 94:F260–F264CrossRefPubMed
6.
go back to reference Leonardi M, Ferro S, Agati R, Fiorani L, Righini A, Cristina E, D'Alessandro R (1994) Interobserver variability in CT assessment of brain atrophy. Neuroradiology 36:17–19CrossRefPubMed Leonardi M, Ferro S, Agati R, Fiorani L, Righini A, Cristina E, D'Alessandro R (1994) Interobserver variability in CT assessment of brain atrophy. Neuroradiology 36:17–19CrossRefPubMed
Metadata
Title
Technical report: 3D printing of the brain for use as a visual-aid tool to communicate MR imaging features of hypoxic ischaemic injury at term with non-physicians
Authors
Savvas Andronikou
Ewan Simpson
Maciej Klemm
Schadie Vedajallam
Anith Chacko
Ngoc Jade Thai
Publication date
01-08-2018
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 8/2018
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-018-3838-2

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