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Published in: European Spine Journal 11/2016

01-11-2016 | Original Article

Tarlov cysts: long-term follow-up after microsurgical inverted plication and sacroplasty

Authors: Ralf Weigel, Manolis Polemikos, Nesrin Uksul, Joachim K. Krauss

Published in: European Spine Journal | Issue 11/2016

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Abstract

Purpose

Surgical treatment of Tarlov cysts is still a matter of debate. Published literature thus far includes mainly small case series with retrospective evaluation and short-term follow-up. We present a novel microsurgical technique that combines the decompression of the nerve fibers with the prevention of recurrence. The long-term follow-up is provided.

Methods

The indication for surgery was incapacitating pain refractory to medical therapy for at least 6 months. The surgical technique consisted in microsurgical opening of the cyst, relief of CSF followed by secured inverted plication of the cyst wall, packing of remnant space with fat graft, and sacroplasty. Pain and neurological deficits were evaluated according to a modified Barrow National Institute score (BNI score, 0–5) and the Departmental Neuro Score (DNS score, 0–20).

Results

A total of 13 patients (9 women, 4 men) were operated and followed up to 14 years (mean FU 5.3 years). Mean age at surgery was 51.8 (±14) years. Pain and neurological deficits improved significantly in 11/13 patients (BNI score pre-OP 5 vs 3.1 ± 1.2 at 1-year-FU, and 2.8 ± 1.2 at last follow-up visit; DNS score pre-OP 5.5 ± 1.5 vs 2.8 ± 2.1 at 1-year follow-up, and 2.6 ± 2.2 at last follow-up visit. Two patients needed revision surgery due to reoccurrence of the cyst. One patient suffered deterioration of preexisting neurological deficit.

Conclusions

The inverted plication technique combined with sacroplasty is a promising technique. It improves pain and neurological deficits on the long term in the majority of patients with symptomatic Tarlov cysts.
Literature
1.
go back to reference Tarlov IM (1938) Perineural cysts of the spinal nerve roots. Arch Neurol Psychiatry 40:1067–1074CrossRef Tarlov IM (1938) Perineural cysts of the spinal nerve roots. Arch Neurol Psychiatry 40:1067–1074CrossRef
3.
go back to reference Marino D, Carluccio MA, Di Donato I, Sicurelli F, Chini E, Mammarella LDT, Rossi F, Rubegni A, Federico A (2013) Tarlov cysts: clinical evaluation of an italian cohort of patients. Neurol Sci Off J Ital Neurol Soc Ital Soc Clin Neurophysiol. doi:10.1007/s10072-013-1321-0 Marino D, Carluccio MA, Di Donato I, Sicurelli F, Chini E, Mammarella LDT, Rossi F, Rubegni A, Federico A (2013) Tarlov cysts: clinical evaluation of an italian cohort of patients. Neurol Sci Off J Ital Neurol Soc Ital Soc Clin Neurophysiol. doi:10.​1007/​s10072-013-1321-0
5.
go back to reference Tarlov IM (1948) Cysts, perineurial, of the sacral roots; another cause, removable, of sciatic pain. JAMA 138:740–744CrossRef Tarlov IM (1948) Cysts, perineurial, of the sacral roots; another cause, removable, of sciatic pain. JAMA 138:740–744CrossRef
6.
go back to reference Araki Y, Tsukaguchi I, Ishida T, Ootani M, Yamamoto T, Tomoda K, Mitomo M (1992) MRI of symptomatic sacral perineural cyst. Radiat Med 10:250–252PubMed Araki Y, Tsukaguchi I, Ishida T, Ootani M, Yamamoto T, Tomoda K, Mitomo M (1992) MRI of symptomatic sacral perineural cyst. Radiat Med 10:250–252PubMed
7.
8.
go back to reference Zhang T, Li Z, Gong W, Sun B, Liu S, Zhang K, Yin D, Xu P, Jia T (2007) Percutaneous fibrin glue therapy for meningeal cysts of the sacral spine with or without aspiration of the cerebrospinal fluid. J Neurosurg Spine 7:145–150. doi:10.3171/spi-07/08/145 CrossRefPubMed Zhang T, Li Z, Gong W, Sun B, Liu S, Zhang K, Yin D, Xu P, Jia T (2007) Percutaneous fibrin glue therapy for meningeal cysts of the sacral spine with or without aspiration of the cerebrospinal fluid. J Neurosurg Spine 7:145–150. doi:10.​3171/​spi-07/​08/​145 CrossRefPubMed
11.
go back to reference Paulsen RD, Call GA, Murtagh FR (1994) Prevalence and percutaneous drainage of cysts of the sacral nerve root sheath (Tarlov cysts). AJNR Am J Neuroradiol 15:293–297PubMed Paulsen RD, Call GA, Murtagh FR (1994) Prevalence and percutaneous drainage of cysts of the sacral nerve root sheath (Tarlov cysts). AJNR Am J Neuroradiol 15:293–297PubMed
12.
go back to reference Langdown AJ, Grundy JR, Birch NC (2005) The clinical relevance of Tarlov cysts. J Spinal Disord Tech 18:29–33CrossRefPubMed Langdown AJ, Grundy JR, Birch NC (2005) The clinical relevance of Tarlov cysts. J Spinal Disord Tech 18:29–33CrossRefPubMed
14.
go back to reference Murphy K, Oaklander AL, Elias G, Kathuria S, Long DM (2016) Treatment of 213 patients with symptomatic Tarlov cysts by CT-guided percutaneous injection of fibrin sealant. AJNR Am J Neuroradiol 37:373–379. doi:10.3174/ajnr.A4517 CrossRefPubMed Murphy K, Oaklander AL, Elias G, Kathuria S, Long DM (2016) Treatment of 213 patients with symptomatic Tarlov cysts by CT-guided percutaneous injection of fibrin sealant. AJNR Am J Neuroradiol 37:373–379. doi:10.​3174/​ajnr.​A4517 CrossRefPubMed
16.
go back to reference Mummaneni PV, Pitts LH, McCormack BM, Corroo JM, Weinstein PR (2000) Microsurgical treatment of symptomatic sacral Tarlov cysts. Neurosurgery 47:74–78PubMed Mummaneni PV, Pitts LH, McCormack BM, Corroo JM, Weinstein PR (2000) Microsurgical treatment of symptomatic sacral Tarlov cysts. Neurosurgery 47:74–78PubMed
18.
go back to reference Voyadzis JM, Bhargava P, Henderson FC (2001) Tarlov cysts: a study of ten cases with review of the literature. J Neurosurg 95:25–32PubMed Voyadzis JM, Bhargava P, Henderson FC (2001) Tarlov cysts: a study of ten cases with review of the literature. J Neurosurg 95:25–32PubMed
20.
go back to reference Burke JF, Thawani JP, Berger I, Nayak NR, Stephen JH, Farkas T, Aschyan HJ, Pierce J, Kanchwala S, Long DM, Welch WC (2016) Microsurgical treatment of sacral perineural (Tarlov) cysts: case series and review of the literature. J Neurosurg Spine 24:700–707. doi:10.3171/2015.9.spine153 CrossRefPubMed Burke JF, Thawani JP, Berger I, Nayak NR, Stephen JH, Farkas T, Aschyan HJ, Pierce J, Kanchwala S, Long DM, Welch WC (2016) Microsurgical treatment of sacral perineural (Tarlov) cysts: case series and review of the literature. J Neurosurg Spine 24:700–707. doi:10.​3171/​2015.​9.​spine153 CrossRefPubMed
21.
go back to reference Caspar W, Papavero L, Nabhan A, Loew C, Ahlhelm F (2003) Microsurgical excision of symptomatic sacral perineurial cysts: a study of 15 cases. Surg Neurol 59:101–105CrossRefPubMed Caspar W, Papavero L, Nabhan A, Loew C, Ahlhelm F (2003) Microsurgical excision of symptomatic sacral perineurial cysts: a study of 15 cases. Surg Neurol 59:101–105CrossRefPubMed
22.
go back to reference Freidenstein J, Aldrete JA, Ness T (2012) Minimally invasive interventional therapy for Tarlov cysts causing symptoms of interstitial cystitis. Pain Phys 15:141–146 Freidenstein J, Aldrete JA, Ness T (2012) Minimally invasive interventional therapy for Tarlov cysts causing symptoms of interstitial cystitis. Pain Phys 15:141–146
25.
go back to reference Neulen A, Kantelhardt SR, Pilgram-Pastor SM, Metz I, Rohde V, Giese A (2011) Microsurgical fenestration of perineural cysts to the thecal sac at the level of the distal dural sleeve. Acta Neurochir (Wien) 153:1427–1434. doi:10.1007/s00701-011-1043-0 (discussion 1434) CrossRef Neulen A, Kantelhardt SR, Pilgram-Pastor SM, Metz I, Rohde V, Giese A (2011) Microsurgical fenestration of perineural cysts to the thecal sac at the level of the distal dural sleeve. Acta Neurochir (Wien) 153:1427–1434. doi:10.​1007/​s00701-011-1043-0 (discussion 1434) CrossRef
26.
go back to reference Tanaka M, Nakahara S, Ito Y, Nakanishi K, Sugimoto Y, Ikuma H, Ozaki T (2006) Surgical results of sacral perineural (Tarlov) cysts. Acta Med Okayama 60:65–70PubMed Tanaka M, Nakahara S, Ito Y, Nakanishi K, Sugimoto Y, Ikuma H, Ozaki T (2006) Surgical results of sacral perineural (Tarlov) cysts. Acta Med Okayama 60:65–70PubMed
28.
go back to reference Lee JY, Impekoven P, Stenzel W, Lohr M, Ernestus RI, Klug N (2004) CT-guided percutaneous aspiration of Tarlov cyst as a useful diagnostic procedure prior to operative intervention. Acta Neurochir (Wien) 146:667–670. doi:10.1007/s00701-004-0274-8 CrossRef Lee JY, Impekoven P, Stenzel W, Lohr M, Ernestus RI, Klug N (2004) CT-guided percutaneous aspiration of Tarlov cyst as a useful diagnostic procedure prior to operative intervention. Acta Neurochir (Wien) 146:667–670. doi:10.​1007/​s00701-004-0274-8 CrossRef
32.
go back to reference Rogers CL, Shetter AG, Fiedler JA, Smith KA, Han PP, Speiser BL (2000) Gamma knife radiosurgery for trigeminal neuralgia: the initial experience of The Barrow Neurological Institute. Int J Radiat Oncol Biol Phys 47:1013–1019CrossRefPubMed Rogers CL, Shetter AG, Fiedler JA, Smith KA, Han PP, Speiser BL (2000) Gamma knife radiosurgery for trigeminal neuralgia: the initial experience of The Barrow Neurological Institute. Int J Radiat Oncol Biol Phys 47:1013–1019CrossRefPubMed
33.
37.
38.
go back to reference Bartels RH, van Overbeeke JJ (1997) Lumbar cerebrospinal fluid drainage for symptomatic sacral nerve root cysts: an adjuvant diagnostic procedure and/or alternative treatment? Technical case report. Neurosurgery 40:861–864CrossRefPubMed Bartels RH, van Overbeeke JJ (1997) Lumbar cerebrospinal fluid drainage for symptomatic sacral nerve root cysts: an adjuvant diagnostic procedure and/or alternative treatment? Technical case report. Neurosurgery 40:861–864CrossRefPubMed
41.
go back to reference Peh WC, Evans NS (1992) Tarlov cysts—another cause of sacral insufficiency fractures? Clin Radiol 46:329–330CrossRefPubMed Peh WC, Evans NS (1992) Tarlov cysts—another cause of sacral insufficiency fractures? Clin Radiol 46:329–330CrossRefPubMed
42.
go back to reference Yucesoy K, Naderi S, Ozer H, Arda MN (1999) Surgical treatment of sacral perineural cysts. A case report. Kobe J Med Sci 45:245–250PubMed Yucesoy K, Naderi S, Ozer H, Arda MN (1999) Surgical treatment of sacral perineural cysts. A case report. Kobe J Med Sci 45:245–250PubMed
44.
go back to reference Wilkins RH (1996) Intraspinal cysts. In: Wilkins RH, Rengachary SS (eds) Neurosurgery. McGraw-Hill, New York, pp 2061–2070 Wilkins RH (1996) Intraspinal cysts. In: Wilkins RH, Rengachary SS (eds) Neurosurgery. McGraw-Hill, New York, pp 2061–2070
46.
go back to reference Acosta FL Jr, Quinones-Hinojosa A, Schmidt MH, Weinstein PR (2003) Diagnosis and management of sacral Tarlov cysts. Case report and review of the literature. Neurosurg Focus 15:E15CrossRefPubMed Acosta FL Jr, Quinones-Hinojosa A, Schmidt MH, Weinstein PR (2003) Diagnosis and management of sacral Tarlov cysts. Case report and review of the literature. Neurosurg Focus 15:E15CrossRefPubMed
48.
go back to reference Tan CF, Wong HF, Ng KK, Wai YY, Wan YL (2001) The fate of epidural autologous free fat grafts; longitudinal MRI surveillance. Transpl Proc 33:631–632CrossRef Tan CF, Wong HF, Ng KK, Wai YY, Wan YL (2001) The fate of epidural autologous free fat grafts; longitudinal MRI surveillance. Transpl Proc 33:631–632CrossRef
Metadata
Title
Tarlov cysts: long-term follow-up after microsurgical inverted plication and sacroplasty
Authors
Ralf Weigel
Manolis Polemikos
Nesrin Uksul
Joachim K. Krauss
Publication date
01-11-2016
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 11/2016
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-016-4744-5

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