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Breast Cancer Research
Published in: Breast Cancer Research 3/2009

01-12-2009 | Short communication

Tailored targeted therapy for all: a realistic and worthwhile objective?

Author: Per Eystein Lønning

Published in: Breast Cancer Research | Special Issue 3/2009

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Excerpt

Tailored therapy has become a term popularly used (and misused) with respect to cancer therapy. Everybody spots the difference between having a full tailormade suit or dress versus simply cutting the last 5 cm off the legs of some readymade trousers to fit your length. In parallel, tailormade therapy should not be confused with implementing simple prognostic or predictive factors. These parameters, in general, do not define direct biological targets, but rather biological parameters revealing a variable statistical correlation to outcome [1]. Taking the analogy of clothes manufacturing, the definition of tailored therapy (made for you) should implement targeted therapies based on identification of individual therapeutic targets such as HER2 in the tumour tissue [2], providing a target exclusive to this tumour for therapeutic attack [3]. …
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Metadata
Title
Tailored targeted therapy for all: a realistic and worthwhile objective?
Author
Per Eystein Lønning
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 3/2009
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr2426

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