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Published in: Acta Neurologica Belgica 3/2013

01-09-2013 | Original Article

TAFI gene polymorphisms in patients with cerebral venous thrombosis

Authors: Serhat Tokgoz, Ayse Gul Zamani, Hatice Gul Durakbasi-Dursun, Osman Yılmaz, Nurhan Ilhan, Sennur Demirel, Mithat Tavli, Alper Sinan

Published in: Acta Neurologica Belgica | Issue 3/2013

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Abstract

Gene polymorphisms of thrombin activatable fibrinolysis inhibition (TAFI) factor have been investigated in various studies in terms of etiology (recurrence) and treatment (fibrinolytic effect) of thrombus formation. Cerebral venous thrombosis (CVT) is a life-threatening disease observed in young persons. Fifty-nine patients with CVT and 100 healthy control subjects were enrolled in the case/control study. The association between TAFI gene polymorphisms −438G>A, +505A>G and +1040C>T and cerebral venous thrombosis was investigated. It was found that frequencies of polymorphic genotype and allele were not different in patients than in control group and that they were not significant for cerebral venous thrombosis.
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Metadata
Title
TAFI gene polymorphisms in patients with cerebral venous thrombosis
Authors
Serhat Tokgoz
Ayse Gul Zamani
Hatice Gul Durakbasi-Dursun
Osman Yılmaz
Nurhan Ilhan
Sennur Demirel
Mithat Tavli
Alper Sinan
Publication date
01-09-2013
Publisher
Springer Milan
Published in
Acta Neurologica Belgica / Issue 3/2013
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI
https://doi.org/10.1007/s13760-012-0170-6

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