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Published in: Journal of Cardiovascular Magnetic Resonance 1/2012

Open Access 01-12-2012 | Poster presentation

T2-dependent errors in MOLLI T1 values: simulations, phantoms, and in-vivo studies

Authors: Kelvin Chow, Jacqueline Flewitt, Joseph J Pagano, Jordin D Green, Matthias G Friedrich, Richard B Thompson

Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2012

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Excerpt

Diffuse myocardial fibrosis occurs in various cardiomyopathies and can be indirectly assessed with blood and myocardial T1 mapping at baseline and after gadolinium administration. The widely used MOdified Look-Locker Inversion-recovery (MOLLI) [1] sequence is known to underestimate myocardial T1 at higher heart rates, but its dependence on T2 has not been explored. We investigate MOLLI’s T1 accuracy in phantoms and confirm with simulations and in-vivo studies. T1 values are further compared with a saturation-recovery T1 mapping sequence [2]. …
Literature
1.
go back to reference Messroghli DR, et al: MRM. 2004, 52: 141-146. Messroghli DR, et al: MRM. 2004, 52: 141-146.
2.
go back to reference Chow K, et al: JCMR. 2011, 13 (Suppl 1): P31- Chow K, et al: JCMR. 2011, 13 (Suppl 1): P31-
Metadata
Title
T2-dependent errors in MOLLI T1 values: simulations, phantoms, and in-vivo studies
Authors
Kelvin Chow
Jacqueline Flewitt
Joseph J Pagano
Jordin D Green
Matthias G Friedrich
Richard B Thompson
Publication date
01-12-2012
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1532-429X-14-S1-P281

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