Published in:
Open Access
01-12-2012 | Poster presentation
T2-dependent errors in MOLLI T1 values: simulations, phantoms, and in-vivo studies
Authors:
Kelvin Chow, Jacqueline Flewitt, Joseph J Pagano, Jordin D Green, Matthias G Friedrich, Richard B Thompson
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2012
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Excerpt
Diffuse myocardial fibrosis occurs in various cardiomyopathies and can be indirectly assessed with blood and myocardial T
1 mapping at baseline and after gadolinium administration. The widely used MOdified Look-Locker Inversion-recovery (MOLLI) [
1] sequence is known to underestimate myocardial T
1 at higher heart rates, but its dependence on T
2 has not been explored. We investigate MOLLI’s T
1 accuracy in phantoms and confirm with simulations and in-vivo studies. T
1 values are further compared with a saturation-recovery T
1 mapping sequence [
2]. …