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Annals of General Psychiatry
Published in: Annals of General Psychiatry 1/2010

Open Access 01-04-2010 | Meeting abstract

Synthesis and study the analgesic and anti-inflammatory effects of rigid benzofurane 3, 4 dihydroxy chalcon (DHC) in mice

Authors: Mahmoud Reza Heidari, Mohammad Heidari, Alireza Foroumadi, Ali Asadipour, Hojat Noroozi

Published in: Annals of General Psychiatry | Special Issue 1/2010

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Excerpt

According to bibliography on the structure activity relationship, it seems that the rigid Benzofuran dihydroxy chalcon (DHC) may be more effective on pain and inflammation. In this study the Rigid benzofuran DHC were synthesized and the analgesic and anti-inflammatory effect was evaluated. …
Literature
1.
Hsieh HK, Lee TH, Wang JP, et al: synthesis and anti - inflammatory effect of chalcones and related compounds. Pharm Res. 1998, 15 (1): 39-46. 10.1023/A:1011940401754.CrossRefPubMed
2.
Sogawa S, Nihro Y, Ueda H, et al: 3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors. J Med Chem. 1993, 36: 3904-3909. 10.1021/jm00076a019.CrossRefPubMed
Metadata
Title
Synthesis and study the analgesic and anti-inflammatory effects of rigid benzofurane 3, 4 dihydroxy chalcon (DHC) in mice
Authors
Mahmoud Reza Heidari
Mohammad Heidari
Alireza Foroumadi
Ali Asadipour
Hojat Noroozi
Publication date
01-04-2010
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue Special Issue 1/2010
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/1744-859X-9-S1-S124

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