Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Surgery Today
Published in: Surgery Today 4/2013

01-04-2013 | Case Report

Synchronous double cancers of primary hepatic adenosquamous carcinoma and hepatocellular carcinoma: report of a case

Authors: Seiichi Shimizu, Akihiko Oshita, Hirotaka Tashiro, Hironobu Amano, Tsuyoshi Kobayashi, Maiko Tanaka, Koji Arihiro, Hideki Ohdan

Published in: Surgery Today | Issue 4/2013

Login to get access

Abstract

A 76-year-old male was referred for the treatment of liver tumors detected by abdominal computed tomography (CT). Dynamic CT revealed a low-density tumor with an irregularly enhanced rim in the left lateral sector, and a highly enhanced, well-circumscribed tumor in the caudate lobe, accompanied by dilation of the intrahepatic biliary ducts in the left lobe. Preoperative imaging studies led to the diagnosis of double cancers consisting of intrahepatic cholangiocarcinoma and hepatocellular carcinoma (HCC). Left hemihepatectomy with caudate lobectomy was performed. The postoperative course was uneventful. Microscopic evaluation revealed that the tumor in the left lateral sector was adenosquamous carcinoma (ASC), whereas that in the caudate lobe was HCC. This report presents the first case describing the resection of synchronous double cancers of primary hepatic ASC and HCC.
Literature
1.
Watanabe T, Sakata J, Ishikawa T, Shirai Y, Suda T, Hirono H, et al. Synchronous development of HCC and CCC in the same subsegment of the liver in a patient with type C liver cirrhosis. World J Hepatol. 2009;1(1):103–9.PubMedCrossRef
2.
Zhang Z, Nonaka H, Nagayama T, Hatori T, Ihara F, Zhang L, et al. Double cancer consisting of adenosquamous and hepatocellular carcinomas of the liver. Pathol Int. 2001;51:961–4.PubMedCrossRef
3.
Dong Y, Wang J, Ma H, Zhou H, Lu G, Zhou X. Primary adenosquamous carcinoma of the colon: report of five cases. Surg Today. 2009;39:619–23.PubMedCrossRef
4.
Asai K, Watanabe M, Matsukiyo H, Osawa A, Saito T, Haiwara O, et al. Pancreatic adenosquamous carcinoma presenting as spleen rupture: report of a case. Surg Today. 2011;41:872–6.PubMedCrossRef
5.
Barr RJ, Hancock DE. Adenosquamous carcinoma of the liver. Gastroenterology. 1975;69:1326–30.PubMed
6.
Kobayashi M, Okabayashi T, Okamoto K, Namikawa T, Araki K. A clinicopathologic study of primary adenosquamous carcinoma of the liver. J Clin Gastroenterol. 2005;39:544–8.PubMedCrossRef
7.
Fujiwara N, Baba H, Nakamura H, Kuwabara H, Tamai S, Nakajima K, et al. A case of adenosquamous carcinoma of the liver (in Japanese). Gan to Kagakuryoho (Jpn J Cancer Chemotherapy). 2009;36:2392–4.
8.
Yokota H, Matoba M, Tonami H, Hasegawa T, Saito H, Kurose N. Imaging findings in primary adenosquamous carcinoma of the liver: a case report. Clin Imaging. 2007;31:279–82.PubMedCrossRef
9.
Shin JU, Jung JT, You SS, Kwon JG, Kim EY, Lee CH, et al. A case of primary adenosquamous carcinoma of the liver with formation of colonic fistula (in Korean with English abstract). Korean J Gastroenterol. 2006;48:360–4.PubMed
10.
Demir G, Yanmaz T, Celik AF, Ozbay G, Serdengecti S. Primary adenosquamous carcinoma of the liver: case with the longest survival. J Clin Gastroenterol. 2005;39:924–5.PubMedCrossRef
11.
Gu MJ, Choi JH, Park WK, Chang JC, Kim HJ. Primary adenosquamous carcinoma of the liver: a case report (in Korean with English abstract). Korean J Hepatol. 2005;11:86–9.PubMed
12.
Nakai T, Ono K, Terayama K, Yamagami T, Nishimura T. Case report: adenosquamous carcinoma of the liver successfully treated with repeated transcatheter arterial infusion chemotherapy (TACE) with degradable starch microspheres. Br J Radiol. 2004;77:516–8.PubMedCrossRef
13.
Kudo M, Arii S, Ikai I, Omata M, Kamishiro M, Sakamoto R, et al. Report of the 18th follow-up survey of primary liver cancer in Japan (in Japanese with English abstract). Kanzo. 2010;51:460–84.CrossRef
14.
Nakajima T, Kondo Y. A clinicopathologic study of intrahepatic cholangiocarcinoma containing a component of SCC. Cancer. 1990;65:1401–4.PubMedCrossRef
15.
Totani T, Watanabe Y, Fujii T. Carcinoma arising from the bile duct in choledochal cyst and anomalous arrangement of the pancreatobiliary ductal union (in Japanese). Tan to Sui. 1985;6:525–35.
16.
Nakanuma Y, Terada T, Tanaka Y, Ohta G. Are hepatolithiasis and cholangiocarcinoma aetiologically related? Amorphological study of 12 cases of hepatolithiasia associated with cholangiocarcinoma. Virchows Arch. 1985;406:45–58.CrossRef
17.
Kim YI, Yu ES, Kim ST. Intraductal variant of peripheral cholangiocarcinoma of the liver with Clonorchis sinensis infection. Cancer. 1989;63:1562–6.PubMedCrossRef
18.
Wee A, Ludwig J, Coffey RJ Jr, LaRusso NF, Wiesner RH. Hepatobiliary carcinoma associated with primary sclerosing cholangitis and chronic ulcerative colitis. Hum Pathol. 1985;16:719–26.PubMedCrossRef
19.
Miura F, Takada T, Amano H, Yoshida M, Isaka T, Toyota N, et al. A case of peribiliary cysts accompanying bile duct carcinoma. World J Gastroenterol. 2006;12:4596–8.PubMed
20.
Tomioka T, Tsunoda T, Harada N, Tsuchiya R, Kajiwara Y, Tokunaga S, et al. Adenosquamous carcinoma of the liver. Am J Gastroenterol. 1987;82:1203–6.PubMed
21.
Takahashi H, Hayakawa H, Tanaka M, Okamura K, Kosaka A, Mizumoto R, et al. Primary adenosquamous carcinoma of liver resected by right trisegmentectomy. J Gastroenterol. 1997;32:843–7.PubMedCrossRef
22.
Ono F, Nakamura R, Itoh K, Kondoh N, Noto N. A resected case of primary adenosquamous carcinoma of the liver (in Japanese with English abstract). Nihon Syokakigeka gakkaizasshi (Jpn J Gastroenterol Surg). 2002;35:1803–7.CrossRef
23.
Maeda T, Takenaka K, Taguchi K, Kajiyama K, Shirabe K, Shimada M, et al. Adenosquamous Carcinoma of the Liver. Clinicopathologic Characteristics and Cytokeratin Profile. Cancer. 1997;80:364–71.PubMedCrossRef
24.
Valle J, Wasan H, Palmer DH, Cunningham D, Anthoney A, Maraveyas A, et al. Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer. N Engl J Med. 2010;362:1273–81.PubMedCrossRef
Metadata
Title
Synchronous double cancers of primary hepatic adenosquamous carcinoma and hepatocellular carcinoma: report of a case
Authors
Seiichi Shimizu
Akihiko Oshita
Hirotaka Tashiro
Hironobu Amano
Tsuyoshi Kobayashi
Maiko Tanaka
Koji Arihiro
Hideki Ohdan
Publication date
01-04-2013
Publisher
Springer Japan
Published in
Surgery Today / Issue 4/2013
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-012-0346-y

Other articles of this Issue 4/2013

Surgery Today 4/2013 Go to the issue

Original Article

Preventive effect of sivelestat on postoperative respiratory disorders after thoracic esophagectomy

Original Article

Comparison of the posterior approach and anterior approach for a Kugel repair of treatment of inguinal hernias

Case Report

The calcitonin levels can sometimes mislead parathyroid surgeons in patients with chronic kidney disease and renal hyperparathyroidism: report of a case

Original Article

The effectiveness and appropriate management of abdominal drains in patients undergoing elective liver resection: a retrospective analysis and prospective case series

How to Do It

Tube cavoplasty using autologous vein grafts for resected inferior vena cava reconstruction

Review Article

Management of Barrett’s esophageal carcinoma