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European Journal of Nuclear Medicine and Molecular Imaging
Published in: European Journal of Nuclear Medicine and Molecular Imaging 2/2010

01-02-2010 | Image of the Month

Symmetrical nail bed uptake on a 99mTc-HDP bone scan in a patient with Wegener’s granulomatosis

Authors: Danijela Dejanović, Alice Widding Høyer, Jann Mortensen, Liselotte Højgaard

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 2/2010

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Excerpt

A 99mTc-HDP bone scan was performed in a 48-year-old man because of diffuse pain in the extremities and involuntary weight loss. The planar whole-body scan showed no pathological skeletal uptake. However, a rare symmetrical uptake was detected corresponding to the nail bed of all fingers and toes (top row). Upon clinical examination of the nails there was no obvious visible cause of the scintigraphic findings. The patient was subsequently diagnosed with Wegener’s granulomatosis. After 7 weeks of steroid and cyclophosphamide therapy a repeat bone scan revealed a slight decrease in uptake intensity (bottom row). …
Literature
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Peller PJ, Ho VB, Kransdorf MJ. Extraosseous Tc-99m MDP uptake: a pathophysiologic approach. Radiographics 1993;13(4):715–34.PubMed
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Zaiac MN, Daniel CR 3rd. Nails in systemic disease. Dermatol Ther 2002;15:99–106.CrossRef
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Anders HJ, Haedecke C, Sigl T, Kruger K. Avascular areas on nailfold capillary microscopy of patients with Wegener’s granulomatosis. Clin Rheumatol 2000;19(2):86–8.CrossRefPubMed
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Mohan HK, Groves AM, Clarke SE. Detection of finger clubbing and primary lung tumor on Tc-99 MDP bone scintigraphy in a patient with a scaphoid fracture. Clin Nucl Med 2004;29(7):450–1.CrossRefPubMed
Metadata
Title
Symmetrical nail bed uptake on a 99mTc-HDP bone scan in a patient with Wegener’s granulomatosis
Authors
Danijela Dejanović
Alice Widding Høyer
Jann Mortensen
Liselotte Højgaard
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 2/2010
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-009-1328-1

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