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Intensive Care Medicine
Published in: Intensive Care Medicine 2/2003

01-02-2003 | Correspondence

Survival after drinking lethal dose of acetone

Authors: Virginie Kostusiak, Ramdane Bekkal, Philippe Mateu

Published in: Intensive Care Medicine | Issue 2/2003

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Excerpt

Sir: Acetone, or dimethyl ketone, is a grease organic solvent with brain and pulmonary toxicity. Kidney and liver damage have also been described [1]. This clinical presentation is classically accompanied by hyperglycaemia, metabolic acidosis and acetonuria [2]. The highest reported serum value associated with survival in the literature is 2500 mg/l [2, 3]. We present a case of survival after severe acetone poisoning. …
Literature
1.
Mirchev H (1978) Hepatorenal lesions in acute acetone poisoning. Vutr Boles 17:89–92PubMed
2.
Testud F (2000) In: Bismuth C (ed) Toxicologie clinique, 5th Edn. Flammarion pp 875–880
3.
Zettinig G, WatzingerN, Eber B, Henning G, Klein W (1997) Survival after poisoning due to intake of ten-times lethal dose of acetone. Dtsch Med Wochenschr 122:1489–1492PubMed
4.
Jones AW (2000) Elimination half-life of acetone in humans: case reports and review of the literature. J Anal Toxicol 24:8–10PubMed
5.
Pappas AA, Ackerman BH, Olsen KM, Taylor EH. (1991) Isopropanol ingestion: a report of six episodes with isopropanol and acetone serum concentration time data. J Toxicol Clin Toxicol 29:11–21PubMed
Metadata
Title
Survival after drinking lethal dose of acetone
Authors
Virginie Kostusiak
Ramdane Bekkal
Philippe Mateu
Publication date
01-02-2003
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 2/2003
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-002-1575-0

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