Skip to main content
Top
Published in: European Journal of Clinical Microbiology & Infectious Diseases 11/2005

01-11-2005 | Concise article

Survey of neonatal candidiasis in Greece

Authors: J. Dotis, J. Evdoridou, G. Kremenopoulos, E. Roilides

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 11/2005

Login to get access

Abstract

In order to estimate the extent of neonatal candidiasis in Greece and to identify trends in clinical management, the present study was conducted using a questionnaire directed to Greek neonatologists and pediatric infectious disease specialists. The respondents represented 15 hospitals in the country’s seven largest cities, which are currently the only Greek cities with neonatal intensive care units. Based on the responses, the incidence of neonatal candidiasis was determined to be 1.87 and 1.94 cases per unit-year for the years 2001 and 2002, respectively. Although a shift toward the isolation of non-Candida albicans isolates was noted, C. albicans was still the predominant pathogenic species. Deoxycholate amphotericin B remains the most frequently used antifungal agent in neonatal units nationwide.
Literature
1.
go back to reference Leibovitz E (2002) Neonatal candidiasis: clinical picture, management controversies and consensus, and new therapeutic options. J Antimicrob Chemother 49:69–73CrossRefPubMed Leibovitz E (2002) Neonatal candidiasis: clinical picture, management controversies and consensus, and new therapeutic options. J Antimicrob Chemother 49:69–73CrossRefPubMed
2.
go back to reference Kossoff EH, Buescher ES, Karlowicz MG (1998) Candidemia in a neonatal intensive care unit: trends during fifteen years and clinical features of 111 cases. Pediatr Infect Dis J 17:504–508CrossRefPubMed Kossoff EH, Buescher ES, Karlowicz MG (1998) Candidemia in a neonatal intensive care unit: trends during fifteen years and clinical features of 111 cases. Pediatr Infect Dis J 17:504–508CrossRefPubMed
3.
go back to reference Kao AS, Brandt ME, Pruitt WR, Conn LA, Perkins BA, Stephens DS, Baughman WS, Reingold AL, Rothrock GA, Pfaller MA, Pinner RW, Hajjeh RA (1999) The epidemiology of candidemia in two United States cities: results of a population-based active surveillance. Clin Infect Dis 29:1164–1170CrossRefPubMed Kao AS, Brandt ME, Pruitt WR, Conn LA, Perkins BA, Stephens DS, Baughman WS, Reingold AL, Rothrock GA, Pfaller MA, Pinner RW, Hajjeh RA (1999) The epidemiology of candidemia in two United States cities: results of a population-based active surveillance. Clin Infect Dis 29:1164–1170CrossRefPubMed
4.
go back to reference Roilides E, Kadiltsoglou I, Zahides D, Bibashi E (1997) Invasive candidosis in pediatric patients. Clin Microbiol Infect 3:192–197PubMedCrossRef Roilides E, Kadiltsoglou I, Zahides D, Bibashi E (1997) Invasive candidosis in pediatric patients. Clin Microbiol Infect 3:192–197PubMedCrossRef
5.
go back to reference Lopez Sastre JB, Coto Cotallo GD, Fernandez Colomer B; Grupo de Hospitales Castrillo (2003) Neonatal invasive candidiasis: a prospective multicenter study of 118 cases. Am J Perinatol 20:153–163CrossRefPubMed Lopez Sastre JB, Coto Cotallo GD, Fernandez Colomer B; Grupo de Hospitales Castrillo (2003) Neonatal invasive candidiasis: a prospective multicenter study of 118 cases. Am J Perinatol 20:153–163CrossRefPubMed
6.
go back to reference Saiman L, Ludington E, Pfaller M, Rangel-Fausto S, Wiblin RT, Dawson J, Blumberg HM, Patterson JE, Rinaldi M, Edwards JE, Wenzel RE, Jarvis W (2000) Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of Mycosis Survey study group. Pediatr Infect Dis J 19:319–324CrossRefPubMed Saiman L, Ludington E, Pfaller M, Rangel-Fausto S, Wiblin RT, Dawson J, Blumberg HM, Patterson JE, Rinaldi M, Edwards JE, Wenzel RE, Jarvis W (2000) Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of Mycosis Survey study group. Pediatr Infect Dis J 19:319–324CrossRefPubMed
7.
go back to reference Nguyen MH, Peacock Jr JE, Morris AJ, Tanner DC, Nguyen ML, Snydman DR, Wagener MM, Rinaldi MG, Yu VL (1996) The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. Am J Med 100:617–623CrossRefPubMed Nguyen MH, Peacock Jr JE, Morris AJ, Tanner DC, Nguyen ML, Snydman DR, Wagener MM, Rinaldi MG, Yu VL (1996) The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. Am J Med 100:617–623CrossRefPubMed
8.
go back to reference Roilides E, Farmaki E, Evdoridou J, Dotis J, Hatziioannidis E, Tsivitanidou M, Bibashi E, Filioti I, Sofianou D, Gil-Lamaignere C, Mueller F-M, Kremenopoulos G (2004) Neonatal candidiasis: analysis of epidemiology drug susceptibility and molecular typing of causative isolates. Eur J Clin Microbiol Infect Dis 23:745–750CrossRefPubMed Roilides E, Farmaki E, Evdoridou J, Dotis J, Hatziioannidis E, Tsivitanidou M, Bibashi E, Filioti I, Sofianou D, Gil-Lamaignere C, Mueller F-M, Kremenopoulos G (2004) Neonatal candidiasis: analysis of epidemiology drug susceptibility and molecular typing of causative isolates. Eur J Clin Microbiol Infect Dis 23:745–750CrossRefPubMed
9.
go back to reference Kaufman D, Fairchild KD (2004) Clinical microbiology of bacterial and fungal sepsis in very-low-birth-weight infants. Clin Microbiol Rev 17:638–680CrossRefPubMed Kaufman D, Fairchild KD (2004) Clinical microbiology of bacterial and fungal sepsis in very-low-birth-weight infants. Clin Microbiol Rev 17:638–680CrossRefPubMed
10.
go back to reference Edwards Jr JE, Bodey GP, Bowden RA, Buchner T, de Pauw BE, Filler SG, Ghannoum MA, Glauser M, Herbrecht R, Kauffman CA, Kohno S, Martino P, Meunier F, Mori T, Pfaller MA, Rex JH, Rogers TR, Rubin RH, Solomkin J, Viscoli C, Walsh TJ, White M (1997) International conference for the development of a consensus on the management and prevention of severe candidal infections. Clin Infect Dis 24:43–59CrossRef Edwards Jr JE, Bodey GP, Bowden RA, Buchner T, de Pauw BE, Filler SG, Ghannoum MA, Glauser M, Herbrecht R, Kauffman CA, Kohno S, Martino P, Meunier F, Mori T, Pfaller MA, Rex JH, Rogers TR, Rubin RH, Solomkin J, Viscoli C, Walsh TJ, White M (1997) International conference for the development of a consensus on the management and prevention of severe candidal infections. Clin Infect Dis 24:43–59CrossRef
11.
go back to reference Karlowicz MG, Hashimoto LN, Kelly Jr RE, Buescher ES (2000) Should central venous catheters be removed as soon as candidemia is detected in neonates? Pediatrics 106:E63CrossRefPubMed Karlowicz MG, Hashimoto LN, Kelly Jr RE, Buescher ES (2000) Should central venous catheters be removed as soon as candidemia is detected in neonates? Pediatrics 106:E63CrossRefPubMed
12.
go back to reference Chapman RL, Faix RG (2000) Persistently positive cultures and outcome in invasive neonatal candidiasis. Pediatr Infect Dis J 19:822–827PubMedCrossRef Chapman RL, Faix RG (2000) Persistently positive cultures and outcome in invasive neonatal candidiasis. Pediatr Infect Dis J 19:822–827PubMedCrossRef
13.
go back to reference Noyola DE, Fernandez M, Moylett EH, Baker CJ (2001) Ophthalmologic, visceral, and cardiac involvement in neonates with candidemia. Clin Infect Dis 32:1018–1023CrossRefPubMed Noyola DE, Fernandez M, Moylett EH, Baker CJ (2001) Ophthalmologic, visceral, and cardiac involvement in neonates with candidemia. Clin Infect Dis 32:1018–1023CrossRefPubMed
14.
go back to reference Bryant K, Maxfield C, Rabalais G (1999) Renal candidiasis in neonates with `. Pediatr Infect Dis J 18:959–963CrossRefPubMed Bryant K, Maxfield C, Rabalais G (1999) Renal candidiasis in neonates with `. Pediatr Infect Dis J 18:959–963CrossRefPubMed
15.
go back to reference Odio CM, Araya R, Pinto LE, Castro CE, Vasquez S, Alfaro B, Saenz A, Herrera ML, Walsh TJ (2004) Caspofungin therapy of neonates with invasive candidiasis. Pediatr Infect Dis J 23:1093–1097PubMed Odio CM, Araya R, Pinto LE, Castro CE, Vasquez S, Alfaro B, Saenz A, Herrera ML, Walsh TJ (2004) Caspofungin therapy of neonates with invasive candidiasis. Pediatr Infect Dis J 23:1093–1097PubMed
16.
17.
go back to reference van den Anker JN, van Popele NML, Sauer PJJ (1995) Antifungal agents in neonatal systemic candidiasis. Antimicrob Agents Chemother 39:1391–1397PubMed van den Anker JN, van Popele NML, Sauer PJJ (1995) Antifungal agents in neonatal systemic candidiasis. Antimicrob Agents Chemother 39:1391–1397PubMed
Metadata
Title
Survey of neonatal candidiasis in Greece
Authors
J. Dotis
J. Evdoridou
G. Kremenopoulos
E. Roilides
Publication date
01-11-2005
Publisher
Springer-Verlag
Published in
European Journal of Clinical Microbiology & Infectious Diseases / Issue 11/2005
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-005-0022-x

Other articles of this Issue 11/2005

European Journal of Clinical Microbiology & Infectious Diseases 11/2005 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine