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Published in: Health Research Policy and Systems 1/2009

Open Access 01-12-2009 | Guide

SUPPORT Tools for evidence-informed health Policymaking (STP) 8: Deciding how much confidence to place in a systematic review

Authors: Simon Lewin, Andrew D Oxman, John N Lavis, Atle Fretheim

Published in: Health Research Policy and Systems | Special Issue 1/2009

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Abstract

This article is part of a series written for people responsible for making decisions about health policies and programmes and for those who support these decision makers.
The reliability of systematic reviews of the effects of health interventions is variable. Consequently, policymakers and others need to assess how much confidence can be placed in such evidence. The use of systematic and transparent processes to determine such decisions can help to prevent the introduction of errors and bias in these judgements. In this article, we suggest five questions that can be considered when deciding how much confidence to place in the findings of a systematic review of the effects of an intervention. These are: 1. Did the review explicitly address an appropriate policy or management question? 2. Were appropriate criteria used when considering studies for the review? 3. Was the search for relevant studies detailed and reasonably comprehensive? 4. Were assessments of the studies' relevance to the review topic and of their risk of bias reproducible? 5. Were the results similar from study to study?
Appendix
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Literature
1.
go back to reference Lavis JN, Oxman AD, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). Introduction. Health Res Policy Syst. 2009, 7 (Suppl 1): I1-10.1186/1478-4505-7-S1-I1.PubMedCentralCrossRefPubMed Lavis JN, Oxman AD, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). Introduction. Health Res Policy Syst. 2009, 7 (Suppl 1): I1-10.1186/1478-4505-7-S1-I1.PubMedCentralCrossRefPubMed
2.
go back to reference Lavis JN, Posada FB, Haines A, Osei E: Use of research to inform public policymaking. Lancet. 2004, 364: 1615-21. 10.1016/S0140-6736(04)17317-0.CrossRefPubMed Lavis JN, Posada FB, Haines A, Osei E: Use of research to inform public policymaking. Lancet. 2004, 364: 1615-21. 10.1016/S0140-6736(04)17317-0.CrossRefPubMed
3.
go back to reference Oxman AD, Lavis JN, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 1. What is evidence-informed policymaking. Health Res Policy Syst. 2009, 7 (Suppl 1): S1-10.1186/1478-4505-7-S1-S1.PubMedCentralCrossRefPubMed Oxman AD, Lavis JN, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 1. What is evidence-informed policymaking. Health Res Policy Syst. 2009, 7 (Suppl 1): S1-10.1186/1478-4505-7-S1-S1.PubMedCentralCrossRefPubMed
4.
go back to reference Oxman AD, Fretheim A, Lavis JN, Lewin S: SUPPORT Tools for evidence-informed health Policymaking (STP). 12. Finding and using research evidence about resource use and costs. Health Res Policy Syst. 2009, 7 (Suppl 1): S12-10.1186/1478-4505-7-S1-S12.PubMedCentralCrossRefPubMed Oxman AD, Fretheim A, Lavis JN, Lewin S: SUPPORT Tools for evidence-informed health Policymaking (STP). 12. Finding and using research evidence about resource use and costs. Health Res Policy Syst. 2009, 7 (Suppl 1): S12-10.1186/1478-4505-7-S1-S12.PubMedCentralCrossRefPubMed
5.
go back to reference Renfrew MJ, Craig D, Dyson L, McCormick F, Rice S, King SE, Misso K, Stenhouse E, Williams AF: Breastfeeding promotion for infants in neonatal units: a systematic review and economic analysis. Health Technol Assess. 2009, 13: 1-iv.CrossRefPubMed Renfrew MJ, Craig D, Dyson L, McCormick F, Rice S, King SE, Misso K, Stenhouse E, Williams AF: Breastfeeding promotion for infants in neonatal units: a systematic review and economic analysis. Health Technol Assess. 2009, 13: 1-iv.CrossRefPubMed
6.
go back to reference Grimshaw JM, Thomas RE, MacLennan G, Fraser C, Ramsay CR, Vale L, Whitty P, Eccles MP, Matowe L, Shirran L: Effectiveness and efficiency of guideline dissemination and implementation strategies. Health Technol Assess. 2004, 8: iii-72.CrossRefPubMed Grimshaw JM, Thomas RE, MacLennan G, Fraser C, Ramsay CR, Vale L, Whitty P, Eccles MP, Matowe L, Shirran L: Effectiveness and efficiency of guideline dissemination and implementation strategies. Health Technol Assess. 2004, 8: iii-72.CrossRefPubMed
7.
go back to reference Carlsen B, Glenton C, Pope C: Thou shalt versus thou shalt not: a meta-synthesis of GPs' attitudes to clinical practice guidelines. Br J Gen Pract. 2007, 57: 971-8. 10.3399/096016407782604820.PubMedCentralCrossRefPubMed Carlsen B, Glenton C, Pope C: Thou shalt versus thou shalt not: a meta-synthesis of GPs' attitudes to clinical practice guidelines. Br J Gen Pract. 2007, 57: 971-8. 10.3399/096016407782604820.PubMedCentralCrossRefPubMed
8.
go back to reference Mays N, Pope C, Popay J: Systematically reviewing qualitative and quantitative evidence to inform management and policy-making in the health field. J Health Serv Res Policy. 2005, 10 (Suppl 1): 6-20. 10.1258/1355819054308576.CrossRefPubMed Mays N, Pope C, Popay J: Systematically reviewing qualitative and quantitative evidence to inform management and policy-making in the health field. J Health Serv Res Policy. 2005, 10 (Suppl 1): 6-20. 10.1258/1355819054308576.CrossRefPubMed
9.
go back to reference Munro SA, Lewin SA, Smith HJ, Engel ME, Fretheim A, Volmink J: Patient adherence to tuberculosis treatment: a systematic review of qualitative research. PLoS Med. 2007, 4: e238-10.1371/journal.pmed.0040238.PubMedCentralCrossRefPubMed Munro SA, Lewin SA, Smith HJ, Engel ME, Fretheim A, Volmink J: Patient adherence to tuberculosis treatment: a systematic review of qualitative research. PLoS Med. 2007, 4: e238-10.1371/journal.pmed.0040238.PubMedCentralCrossRefPubMed
10.
go back to reference Pound P, Britten N, Morgan M, Yardley L, Pope C, Daker-White G, Campbell R: Resisting medicines: a synthesis of qualitative studies of medicine taking. Soc Sci Med. 2005, 61: 133-55. 10.1016/j.socscimed.2004.11.063.CrossRefPubMed Pound P, Britten N, Morgan M, Yardley L, Pope C, Daker-White G, Campbell R: Resisting medicines: a synthesis of qualitative studies of medicine taking. Soc Sci Med. 2005, 61: 133-55. 10.1016/j.socscimed.2004.11.063.CrossRefPubMed
11.
go back to reference Laurant M, Reeves D, Hermens R, Braspenning J, Grol R, Sibbald B: Substitution of doctors by nurses in primary care. Cochrane Database Syst Rev. 2005, 2: CD001271-PubMed Laurant M, Reeves D, Hermens R, Braspenning J, Grol R, Sibbald B: Substitution of doctors by nurses in primary care. Cochrane Database Syst Rev. 2005, 2: CD001271-PubMed
12.
go back to reference Forsetlund L, Bjorndal A, Rashidian A, Jamtvedt G, O'Brien MA, Wolf F, Davis D, Odgaard-Jensen J, Oxman AD: Continuing education meetings and workshops: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2009, 2: CD003030-PubMed Forsetlund L, Bjorndal A, Rashidian A, Jamtvedt G, O'Brien MA, Wolf F, Davis D, Odgaard-Jensen J, Oxman AD: Continuing education meetings and workshops: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2009, 2: CD003030-PubMed
14.
go back to reference Oxman AD, Schunemann HJ, Fretheim A: Improving the use of research evidence in guideline development: 8. Synthesis and presentation of evidence. Health Res Policy Syst. 2006, 4: 20-10.1186/1478-4505-4-20.PubMedCentralCrossRefPubMed Oxman AD, Schunemann HJ, Fretheim A: Improving the use of research evidence in guideline development: 8. Synthesis and presentation of evidence. Health Res Policy Syst. 2006, 4: 20-10.1186/1478-4505-4-20.PubMedCentralCrossRefPubMed
15.
go back to reference Oxman AD, Glasziou P, Williams JW: What should clinicians do when faced with conflicting recommendations?. BMJ. 2008, 337: a2530-10.1136/bmj.a2530.CrossRefPubMed Oxman AD, Glasziou P, Williams JW: What should clinicians do when faced with conflicting recommendations?. BMJ. 2008, 337: a2530-10.1136/bmj.a2530.CrossRefPubMed
16.
go back to reference Jadad AR, Cook DJ, Jones A, Klassen TP, Tugwell P, Moher M, Moher D: Methodology and reports of systematic reviews and meta-analyses: a comparison of Cochrane reviews with articles published in paper-based journals. JAMA. 1998, 280: 278-80. 10.1001/jama.280.3.278.CrossRefPubMed Jadad AR, Cook DJ, Jones A, Klassen TP, Tugwell P, Moher M, Moher D: Methodology and reports of systematic reviews and meta-analyses: a comparison of Cochrane reviews with articles published in paper-based journals. JAMA. 1998, 280: 278-80. 10.1001/jama.280.3.278.CrossRefPubMed
17.
go back to reference Jorgensen AW, Hilden J, Gotzsche PC: Cochrane reviews compared with industry supported meta-analyses and other meta-analyses of the same drugs: systematic review. BMJ. 2006, 333: 782-10.1136/bmj.38973.444699.0B.PubMedCentralCrossRefPubMed Jorgensen AW, Hilden J, Gotzsche PC: Cochrane reviews compared with industry supported meta-analyses and other meta-analyses of the same drugs: systematic review. BMJ. 2006, 333: 782-10.1136/bmj.38973.444699.0B.PubMedCentralCrossRefPubMed
18.
go back to reference Dixon E, Hameed M, Sutherland F, Cook DJ, Doig C: Evaluating meta-analyses in the general surgical literature: a critical appraisal. Ann Surg. 2005, 241: 450-9. 10.1097/01.sla.0000154258.30305.df.PubMedCentralCrossRefPubMed Dixon E, Hameed M, Sutherland F, Cook DJ, Doig C: Evaluating meta-analyses in the general surgical literature: a critical appraisal. Ann Surg. 2005, 241: 450-9. 10.1097/01.sla.0000154258.30305.df.PubMedCentralCrossRefPubMed
19.
20.
go back to reference Jadad AR, Moher M, Browman GP, Booker L, Sigouin C, Fuentes M, Stevens R: Systematic reviews and meta-analyses on treatment of asthma: critical evaluation. BMJ. 2000, 320: 537-40. 10.1136/bmj.320.7234.537.PubMedCentralCrossRefPubMed Jadad AR, Moher M, Browman GP, Booker L, Sigouin C, Fuentes M, Stevens R: Systematic reviews and meta-analyses on treatment of asthma: critical evaluation. BMJ. 2000, 320: 537-40. 10.1136/bmj.320.7234.537.PubMedCentralCrossRefPubMed
21.
go back to reference Linde K, Willich SN: How objective are systematic reviews? Differences between reviews on complementary medicine. J R Soc Med. 2003, 96: 17-22. 10.1258/jrsm.96.1.17.PubMedCentralCrossRefPubMed Linde K, Willich SN: How objective are systematic reviews? Differences between reviews on complementary medicine. J R Soc Med. 2003, 96: 17-22. 10.1258/jrsm.96.1.17.PubMedCentralCrossRefPubMed
22.
go back to reference Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, Porter AC, Tugwell P, Moher D, Bouter LM: Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007, 7: 10-10.1186/1471-2288-7-10.PubMedCentralCrossRefPubMed Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, Porter AC, Tugwell P, Moher D, Bouter LM: Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007, 7: 10-10.1186/1471-2288-7-10.PubMedCentralCrossRefPubMed
24.
go back to reference Oxman AD, Guyatt GH: Validation of an index of the quality of review articles. J Clin Epidemiol. 1991, 44: 1271-8. 10.1016/0895-4356(91)90160-B.CrossRefPubMed Oxman AD, Guyatt GH: Validation of an index of the quality of review articles. J Clin Epidemiol. 1991, 44: 1271-8. 10.1016/0895-4356(91)90160-B.CrossRefPubMed
27.
go back to reference Higgins JPT, Altman DF: Chapter 8: Assessing risk of bias in included studies. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). Edited by: Higgins JPT, Green S. 2008, The Cochrane Collaboration, [http://www.cochrane-handbook.org/]CrossRef Higgins JPT, Altman DF: Chapter 8: Assessing risk of bias in included studies. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). Edited by: Higgins JPT, Green S. 2008, The Cochrane Collaboration, [http://​www.​cochrane-handbook.​org/​]CrossRef
28.
go back to reference Lavis JN, Oxman AD, Souza NM, Lewin S, Gruen RL, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 9. Assessing the applicability of the findings of a systematic review. Health Res Policy Syst. 2009, 7 (Suppl 1): S9-10.1186/1478-4505-7-S1-S9.PubMedCentralCrossRefPubMed Lavis JN, Oxman AD, Souza NM, Lewin S, Gruen RL, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 9. Assessing the applicability of the findings of a systematic review. Health Res Policy Syst. 2009, 7 (Suppl 1): S9-10.1186/1478-4505-7-S1-S9.PubMedCentralCrossRefPubMed
29.
go back to reference Counsell C: Formulating Questions and Locating Primary Studies for Inclusion in Systematic Reviews. Ann Intern Med. 1997, 127: 380-7.CrossRefPubMed Counsell C: Formulating Questions and Locating Primary Studies for Inclusion in Systematic Reviews. Ann Intern Med. 1997, 127: 380-7.CrossRefPubMed
31.
go back to reference Meremikwu MM, Donegan S, Esu E: Chemoprophylaxis and intermittent treatment for preventing malaria in children. Cochrane Database Syst Rev. 2008, 2: CD003756-PubMed Meremikwu MM, Donegan S, Esu E: Chemoprophylaxis and intermittent treatment for preventing malaria in children. Cochrane Database Syst Rev. 2008, 2: CD003756-PubMed
32.
34.
go back to reference Grobler LA, Marais BJ, Mabunda S, Marindi P, Reuter H, Volmink J: Interventions for increasing the proportion of health professionals practicing in underserved communities. Cochrane Database Syst Rev. 2009, 1: CD005314-PubMed Grobler LA, Marais BJ, Mabunda S, Marindi P, Reuter H, Volmink J: Interventions for increasing the proportion of health professionals practicing in underserved communities. Cochrane Database Syst Rev. 2009, 1: CD005314-PubMed
35.
go back to reference Lefebvre C, Manheimer E, Glanville J, on behalf of the Cochrane Information Retrieval Methods Group: Searching for studies. Cochrane Handbook for systematic reviews of interventions. Version 5.0.1 [updated September 2008]. Edited by: Higgins JPT, Green S. 2008, The Cochrane Collaboration, [http://www.cochrane-handbook.org/] Lefebvre C, Manheimer E, Glanville J, on behalf of the Cochrane Information Retrieval Methods Group: Searching for studies. Cochrane Handbook for systematic reviews of interventions. Version 5.0.1 [updated September 2008]. Edited by: Higgins JPT, Green S. 2008, The Cochrane Collaboration, [http://​www.​cochrane-handbook.​org/​]
36.
go back to reference Dickersin K, Min YI: Publication bias: the problem that won't go away. Ann N Y Acad Sci. 1993, 703: 135-46. 10.1111/j.1749-6632.1993.tb26343.x.CrossRefPubMed Dickersin K, Min YI: Publication bias: the problem that won't go away. Ann N Y Acad Sci. 1993, 703: 135-46. 10.1111/j.1749-6632.1993.tb26343.x.CrossRefPubMed
37.
go back to reference Hopewell S, Loudon K, Clarke MJ, Oxman AD, Dickersin K: Publication bias in clinical trials due to statistical significance or direction of trial results. Cochrane Database Syst Rev. 2009, 21 (1): MR000006- Hopewell S, Loudon K, Clarke MJ, Oxman AD, Dickersin K: Publication bias in clinical trials due to statistical significance or direction of trial results. Cochrane Database Syst Rev. 2009, 21 (1): MR000006-
38.
go back to reference Hopewell S, Clarke M, Stewart L, Tierney J: Time to publication for results of clinical trials. Cochrane Database Syst Rev. 2007, 2: MR000011-PubMed Hopewell S, Clarke M, Stewart L, Tierney J: Time to publication for results of clinical trials. Cochrane Database Syst Rev. 2007, 2: MR000011-PubMed
39.
go back to reference Lavis JN, Wilson M, Oxman AD, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 4. Using research evidence to clarify a problem. Health Res Policy Syst. 2009, 7 (Suppl 1): S4-10.1186/1478-4505-7-S1-S4.PubMedCentralCrossRefPubMed Lavis JN, Wilson M, Oxman AD, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 4. Using research evidence to clarify a problem. Health Res Policy Syst. 2009, 7 (Suppl 1): S4-10.1186/1478-4505-7-S1-S4.PubMedCentralCrossRefPubMed
40.
go back to reference Lavis JN, Wilson MG, Oxman AD, Grimshaw J, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 5. Using research evidence to frame options to address a problem. Health Res Policy Syst. 2009, 7 (Suppl 1): S5-10.1186/1478-4505-7-S1-S5.PubMedCentralCrossRefPubMed Lavis JN, Wilson MG, Oxman AD, Grimshaw J, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 5. Using research evidence to frame options to address a problem. Health Res Policy Syst. 2009, 7 (Suppl 1): S5-10.1186/1478-4505-7-S1-S5.PubMedCentralCrossRefPubMed
41.
go back to reference Katrak P, Bialocerkowski A, Massy-Westropp N, Kumar VS, Grimmer K: A systematic review of the content of critical appraisal tools. BMC Medical Research Methodology. 2004, 4: 22-10.1186/1471-2288-4-22.PubMedCentralCrossRefPubMed Katrak P, Bialocerkowski A, Massy-Westropp N, Kumar VS, Grimmer K: A systematic review of the content of critical appraisal tools. BMC Medical Research Methodology. 2004, 4: 22-10.1186/1471-2288-4-22.PubMedCentralCrossRefPubMed
42.
go back to reference Moher D, Jadad AR, Nichol G, Penman M, Tugwell P, Walsh S: Assessing the quality of randomized controlled trials: an annotated bibliography of scales and checklists. Control Clin Trials. 1995, 16: 62-73. 10.1016/0197-2456(94)00031-W.CrossRefPubMed Moher D, Jadad AR, Nichol G, Penman M, Tugwell P, Walsh S: Assessing the quality of randomized controlled trials: an annotated bibliography of scales and checklists. Control Clin Trials. 1995, 16: 62-73. 10.1016/0197-2456(94)00031-W.CrossRefPubMed
43.
go back to reference Shepperd S, Doll H, Broad J, Gladman J, Iliffe S, Langhorne P, Richards S, Martin F, Harris R: Early discharge hospital at home. Cochrane Database Syst Rev. 2009, 1: CD000356-PubMed Shepperd S, Doll H, Broad J, Gladman J, Iliffe S, Langhorne P, Richards S, Martin F, Harris R: Early discharge hospital at home. Cochrane Database Syst Rev. 2009, 1: CD000356-PubMed
44.
go back to reference Lewin SA, Dick J, Pond P, Zwarenstein M, Aja G, van Wyk B, Bosch-Capblanch X, Patrick M: Lay health workers in primary and community health care. Cochrane Database Syst Rev. 2005, 1: CD004015-PubMed Lewin SA, Dick J, Pond P, Zwarenstein M, Aja G, van Wyk B, Bosch-Capblanch X, Patrick M: Lay health workers in primary and community health care. Cochrane Database Syst Rev. 2005, 1: CD004015-PubMed
45.
go back to reference Jamtvedt G, Young JM, Kristoffersen DT, O'Brien MA, Oxman AD: Audit and feedback: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2006, 2: CD000259-PubMed Jamtvedt G, Young JM, Kristoffersen DT, O'Brien MA, Oxman AD: Audit and feedback: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2006, 2: CD000259-PubMed
46.
go back to reference Arblaster L, Lambert M, Entwistle V, Forster M, Fullerton D, Sheldon T, Watt I: A systematic review of the effectiveness of health service interventions aimed at reducing inequalities in health. J Health Serv Res Policy. 1996, 1: 93-103.PubMed Arblaster L, Lambert M, Entwistle V, Forster M, Fullerton D, Sheldon T, Watt I: A systematic review of the effectiveness of health service interventions aimed at reducing inequalities in health. J Health Serv Res Policy. 1996, 1: 93-103.PubMed
47.
go back to reference Moher D, Jadad AR, Klassen TP: Guides for reading and interpreting systematic reviews: III. How did the authors synthesize the data and make their conclusions?. Arch Pediatr Adolesc Med. 1998, 152 (9): 915-20.CrossRefPubMed Moher D, Jadad AR, Klassen TP: Guides for reading and interpreting systematic reviews: III. How did the authors synthesize the data and make their conclusions?. Arch Pediatr Adolesc Med. 1998, 152 (9): 915-20.CrossRefPubMed
48.
go back to reference Oxman AD, Cook DJ, Guyatt GH: Users' guides to the medical literature. VI. How to use an overview. Evidence-Based Medicine Working Group. JAMA. 1994, 272: 1367-71. 10.1001/jama.272.17.1367.CrossRefPubMed Oxman AD, Cook DJ, Guyatt GH: Users' guides to the medical literature. VI. How to use an overview. Evidence-Based Medicine Working Group. JAMA. 1994, 272: 1367-71. 10.1001/jama.272.17.1367.CrossRefPubMed
49.
go back to reference Oxman AD, Lavis JN, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 10. Taking equity into consideration when assessing the findings of a systematic review. Health Res Policy Syst. 2009, 7 (Suppl 1): S10-10.1186/1478-4505-7-S1-S10.PubMedCentralCrossRefPubMed Oxman AD, Lavis JN, Lewin S, Fretheim A: SUPPORT Tools for evidence-informed health Policymaking (STP). 10. Taking equity into consideration when assessing the findings of a systematic review. Health Res Policy Syst. 2009, 7 (Suppl 1): S10-10.1186/1478-4505-7-S1-S10.PubMedCentralCrossRefPubMed
50.
go back to reference Oxman AD, Lavis JN, Fretheim A, Lewin S: SUPPORT Tools for evidence-informed health Policymaking (STP). 17. Dealing with insufficient research evidence. Health Res Policy Syst. 2009, 7 (Suppl 1): S17-10.1186/1478-4505-7-S1-S17.PubMedCentralCrossRefPubMed Oxman AD, Lavis JN, Fretheim A, Lewin S: SUPPORT Tools for evidence-informed health Policymaking (STP). 17. Dealing with insufficient research evidence. Health Res Policy Syst. 2009, 7 (Suppl 1): S17-10.1186/1478-4505-7-S1-S17.PubMedCentralCrossRefPubMed
51.
go back to reference Dixon-Woods M, Agarwal S, Jones D, Young B, Sutton A: Synthesising qualitative and quantitative evidence: a review of possible methods. J Health Serv Res Policy. 2005, 10: 45-53. 10.1258/1355819052801804.CrossRefPubMed Dixon-Woods M, Agarwal S, Jones D, Young B, Sutton A: Synthesising qualitative and quantitative evidence: a review of possible methods. J Health Serv Res Policy. 2005, 10: 45-53. 10.1258/1355819052801804.CrossRefPubMed
52.
go back to reference Noyes J, Popay J, Pearson A, Hannes K, Booth A: Chapter 20: Qualitative research and Cochrane reviews. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). Edited by: Higgins JPT, Green S. 2008, The Cochrane Collaboration, [http://www.cochrane-handbook.org/] Noyes J, Popay J, Pearson A, Hannes K, Booth A: Chapter 20: Qualitative research and Cochrane reviews. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). Edited by: Higgins JPT, Green S. 2008, The Cochrane Collaboration, [http://​www.​cochrane-handbook.​org/​]
53.
go back to reference Lavis JN: Supporting the Use of Systematic Reviews in Policymaking. PLoS Med. 6 (11): e1000141-10.1371/journal.pmed.1000141. Lavis JN: Supporting the Use of Systematic Reviews in Policymaking. PLoS Med. 6 (11): e1000141-10.1371/journal.pmed.1000141.
54.
go back to reference Jefferson T, Demicheli V, Vale L: Quality of systematic reviews of economic evaluations in health care. JAMA. 2002, 287: 2809-12. 10.1001/jama.287.21.2809.CrossRefPubMed Jefferson T, Demicheli V, Vale L: Quality of systematic reviews of economic evaluations in health care. JAMA. 2002, 287: 2809-12. 10.1001/jama.287.21.2809.CrossRefPubMed
55.
go back to reference Siegfried N, Muller M, Deeks JJ, Volmink J: Male circumcision for prevention of heterosexual acquisition of HIV in men. Cochrane Database Syst Rev. 2009, 2: CD003362-PubMed Siegfried N, Muller M, Deeks JJ, Volmink J: Male circumcision for prevention of heterosexual acquisition of HIV in men. Cochrane Database Syst Rev. 2009, 2: CD003362-PubMed
56.
go back to reference McGuinness B, Craig D, Bullock R, Passmore P: Statins for the prevention of dementia. Cochrane Database Syst Rev. 2009, 2: CD003160-PubMed McGuinness B, Craig D, Bullock R, Passmore P: Statins for the prevention of dementia. Cochrane Database Syst Rev. 2009, 2: CD003160-PubMed
Metadata
Title
SUPPORT Tools for evidence-informed health Policymaking (STP) 8: Deciding how much confidence to place in a systematic review
Authors
Simon Lewin
Andrew D Oxman
John N Lavis
Atle Fretheim
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Health Research Policy and Systems / Issue Special Issue 1/2009
Electronic ISSN: 1478-4505
DOI
https://doi.org/10.1186/1478-4505-7-S1-S8

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