Published in:
01-09-2003 | Brief Report
Successful Treatment of an Aspergillus Brain Abscess with Caspofungin: Case Report of a Diabetic Patient Intolerant of Amphotericin B
Authors:
A. L. Colombo, R. C. Rosas
Published in:
European Journal of Clinical Microbiology & Infectious Diseases
|
Issue 9/2003
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Excerpt
Aspergillosis may occur in a variety of clinical settings, including patients undergoing prolonged steroid therapy or cancer chemotherapy, patients who have undergone organ transplantation, or patients infected by the human immunodeficiency virus. Cerebral aspergillosis may occur in up to 20% of all cases of invasive aspergillosis; however, only in rare cases is the brain the sole site of infection [
1]. Brain abscess due to
Aspergillus spp. has been reported infrequently among immunologically competent patients [
2]. We describe a diabetic patient with a brain abscess caused by
Aspergillus spp. who was successfully treated with caspofungin, the first in a new class of antifungal agents known as the glucan synthesis inhibitors. …