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Journal of Interventional Cardiac Electrophysiology

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01-11-2008 | CASE REPORT

Successful transition to buprenorphine in a patient with methadone-induced torsades de pointes

Authors: Jason Levi Esses, Jonathan Rosman, Lien Thanh Do, Paul Schweitzer, Sam Hanon

Published in: Journal of Interventional Cardiac Electrophysiology | Issue 2/2008

Abstract

A 56-year-old-man presented with syncope and torsades de pointes secondary to methadone-induced QT prolongation. After transition from methadone to buprenorphine, a partial μ-opiate-receptor agonist and a κ-opiate-receptor antagonist, the QT normalized and ventricular arrhythmias resolved. Buprenorphine should be used for opiate dependence and chronic pain in patients with methadone-induced QT prolongation and as first line therapy in patients with risk factors for torsades de pointes.

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Title: Successful transition to buprenorphine in a patient with methadone-induced torsades de pointes
Authors: Jason Levi Esses
Jonathan Rosman
Lien Thanh Do
Paul Schweitzer
Sam Hanon
Publication date: 01-11-2008
Publisher: Springer US
Published in: Journal of Interventional Cardiac Electrophysiology / Issue 2/2008
Print ISSN: 1383-875X
Electronic ISSN: 1572-8595
DOI: https://doi.org/10.1007/s10840-008-9280-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Successful transition to buprenorphine in a patient with methadone-induced torsades de pointes

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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