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Journal of Medical Case Reports

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Open Access 01-12-2010 | Case report

Successful stabilisation of nephropathy in a patient with POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome on treatment with mycophenolate and steroids: a case report

Authors: Gareth J Rosser, Pablo Garcia Reitböck, Martin C Gray, Paul Warwicker

Published in: Journal of Medical Case Reports | Issue 1/2010

Abstract

Introduction

Renal involvement in POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome is considered to be an under-diagnosed phenomenon with no clear treatment path. The limited literature suggests steroids to be the drug of choice, although improvements are limited and usually reverse on withdrawal of the drug.

Case presentation

A 52-year-old Caucasian woman presenting with features consistent with POEMS syndrome developed progressive renal impairment with proteinuria. Renal biopsy revealed a membranoproliferative glomerulonephritis. She was treated with relatively low dose oral mycophenolate mofetil and prednisolone which stabilised her nephropathy and neuropathy.

Conclusion

We describe an alternative therapeutic option in patients with this serious but poorly understood condition.

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Title: Successful stabilisation of nephropathy in a patient with POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome on treatment with mycophenolate and steroids: a case report
Authors: Gareth J Rosser
Pablo Garcia Reitböck
Martin C Gray
Paul Warwicker
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2010
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-4-63

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Successful stabilisation of nephropathy in a patient with POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome on treatment with mycophenolate and steroids: a case report

Abstract

Introduction

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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