Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2011

Open Access 01-12-2011 | Case report

Successful pregnancy outcome after laparoscopic-assisted excision of a bizarre leiomyoma: a case report

Authors: Akihiro Takeda, Sanae Imoto, Masahiko Mori, Hiromi Nakamura

Published in: Journal of Medical Case Reports | Issue 1/2011

Login to get access

Abstract

Introduction

Bizarre leiomyoma is a rare leiomyoma variant that requires a precise histopathological evaluation. Especially when diagnosed in a younger woman, this tumor leads to challenging treatment issues involving fertility preservation. Owing to the low incidence of bizarre leiomyoma, there is insufficient evidence to support myomectomy alone as an appropriate management option. Also, the impact of bizarre leiomyoma on fertility is not well known.

Case presentation

A 30-year-old Japanese woman who had never given birth was referred to us because of a uterine tumor with an unusual diagnostic image and was treated by a gasless laparoscopic-assisted excision with a wound retractor. Owing to an unclear margin between her uterine tumor and myometrium, a concomitant excision of adjacent myometrial tissue was required to achieve the maximum resection of her tumor. The histopathological diagnosis was bizarre leiomyoma. Seven months later, she conceived spontaneously and her pregnancy course was uneventful. At 37 weeks of gestation, an elective cesarean section was performed. Although a slight omental adhesion was noted at the postexcisional scar, her uterine wall structure was well preserved and a recurrence of bizarre leiomyoma was not noted.

Conclusions

A laparoscopic-assisted excision of bizarre leiomyoma is a feasible and minimally invasive conservative measure for a woman who wishes to preserve fertility.
Appendix
Available only for authorised users
Literature
1.
go back to reference Solomon LA, Schimp VL, Ali-Fehmi R, Diamond MP, Munkarah AR: Clinical update of smooth muscle tumors of the uterus. J Minim Invasive Gynecol. 2005, 12: 401-408. 10.1016/j.jmig.2005.05.022.CrossRefPubMed Solomon LA, Schimp VL, Ali-Fehmi R, Diamond MP, Munkarah AR: Clinical update of smooth muscle tumors of the uterus. J Minim Invasive Gynecol. 2005, 12: 401-408. 10.1016/j.jmig.2005.05.022.CrossRefPubMed
2.
go back to reference Buttram VC, Reiter RC: Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril. 1981, 36: 433-445.CrossRefPubMed Buttram VC, Reiter RC: Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril. 1981, 36: 433-445.CrossRefPubMed
3.
go back to reference Toledo G, Oliva E: Smooth muscle tumors of the uterus: a practical approach. Arch Pathol Lab Med. 2008, 132: 595-605.PubMed Toledo G, Oliva E: Smooth muscle tumors of the uterus: a practical approach. Arch Pathol Lab Med. 2008, 132: 595-605.PubMed
4.
go back to reference Schwartz LB, Zawin M, Carcangiu ML, Lange R, McCarthy S: Does pelvic magnetic resonance imaging differentiate among the histologic subtypes of uterine leiomyomata?. Fertil Steril. 1998, 70: 580-587. 10.1016/S0015-0282(98)00193-9.CrossRefPubMed Schwartz LB, Zawin M, Carcangiu ML, Lange R, McCarthy S: Does pelvic magnetic resonance imaging differentiate among the histologic subtypes of uterine leiomyomata?. Fertil Steril. 1998, 70: 580-587. 10.1016/S0015-0282(98)00193-9.CrossRefPubMed
5.
go back to reference Downes KA, Hart WR: Bizarre leiomyomas of the uterus: a comprehensive pathologic study of 24 cases with long-term follow-up. Am J Surg Pathol. 1997, 21: 1261-1270. 10.1097/00000478-199711000-00001.CrossRefPubMed Downes KA, Hart WR: Bizarre leiomyomas of the uterus: a comprehensive pathologic study of 24 cases with long-term follow-up. Am J Surg Pathol. 1997, 21: 1261-1270. 10.1097/00000478-199711000-00001.CrossRefPubMed
6.
go back to reference Sung CO, Ahn G, Song SY, Choi YL, Bae DS: Atypical leiomyomas of the uterus with long-term follow-up after myomectomy with immunohistochemical analysis for p16INK4A, p53, Ki-67, estrogen receptors, and progesterone receptors. Int J Gynecol Pathol. 2009, 28: 529-534. 10.1097/PGP.0b013e3181a2b8d3.CrossRefPubMed Sung CO, Ahn G, Song SY, Choi YL, Bae DS: Atypical leiomyomas of the uterus with long-term follow-up after myomectomy with immunohistochemical analysis for p16INK4A, p53, Ki-67, estrogen receptors, and progesterone receptors. Int J Gynecol Pathol. 2009, 28: 529-534. 10.1097/PGP.0b013e3181a2b8d3.CrossRefPubMed
7.
go back to reference Yamashita Y, Torashima M, Takahashi M, Tanaka N, Katabuchi H, Miyazaki K, Ito M, Okamura H: Hyperintense uterine leiomyoma at T2-weighted MR imaging: differentiation with dynamic enhanced MR imaging and clinical implications. Radiology. 1993, 189: 721-725.CrossRefPubMed Yamashita Y, Torashima M, Takahashi M, Tanaka N, Katabuchi H, Miyazaki K, Ito M, Okamura H: Hyperintense uterine leiomyoma at T2-weighted MR imaging: differentiation with dynamic enhanced MR imaging and clinical implications. Radiology. 1993, 189: 721-725.CrossRefPubMed
8.
go back to reference Takeda A, Sakai K, Mitsui T, Nakamura H: Wound retraction system for gasless laparoscopic-assisted myomectomy with a subcutaneous abdominal wall-lift method. J Minim Invasive Gynecol. 2007, 14: 240-246. 10.1016/j.jmig.2006.07.018.CrossRefPubMed Takeda A, Sakai K, Mitsui T, Nakamura H: Wound retraction system for gasless laparoscopic-assisted myomectomy with a subcutaneous abdominal wall-lift method. J Minim Invasive Gynecol. 2007, 14: 240-246. 10.1016/j.jmig.2006.07.018.CrossRefPubMed
9.
go back to reference Takeda A, Koyama K, Imoto S, Mori M, Sakai K, Nakamura H: Temporary endovascular balloon occlusion of the bilateral internal iliac arteries for control of hemorrhage during laparoscopic-assisted myomectomy in a nulligravida with a large cervical myoma. Fertil Steril. 2009, 91: 935.e5-9. 10.1016/j.fertnstert.2008.09.040.CrossRef Takeda A, Koyama K, Imoto S, Mori M, Sakai K, Nakamura H: Temporary endovascular balloon occlusion of the bilateral internal iliac arteries for control of hemorrhage during laparoscopic-assisted myomectomy in a nulligravida with a large cervical myoma. Fertil Steril. 2009, 91: 935.e5-9. 10.1016/j.fertnstert.2008.09.040.CrossRef
10.
go back to reference Vitiello D, McCarthy S: Diagnostic imaging of myomas. Obstet Gynecol Clin N Am. 2006, 33: 85-95. 10.1016/j.ogc.2005.12.013.CrossRef Vitiello D, McCarthy S: Diagnostic imaging of myomas. Obstet Gynecol Clin N Am. 2006, 33: 85-95. 10.1016/j.ogc.2005.12.013.CrossRef
11.
go back to reference Melgrati L, Damiani A, Franzoni G, Marziali M, Sesti F: Isobaric (gasless) laparoscopic myomectomy during pregnancy. J Minim Invasive Gynecol. 2005, 12: 379-381. 10.1016/j.jmig.2005.05.012.CrossRefPubMed Melgrati L, Damiani A, Franzoni G, Marziali M, Sesti F: Isobaric (gasless) laparoscopic myomectomy during pregnancy. J Minim Invasive Gynecol. 2005, 12: 379-381. 10.1016/j.jmig.2005.05.012.CrossRefPubMed
12.
go back to reference Damiani A, Melgrati L, Franzoni G, Stepanyan M, Bonifacio S, Sesti F: Isobaric gasless laparoscopic myomectomy for removal of large uterine leiomyomas. Surg Endosc. 2006, 20: 1406-1409. 10.1007/s00464-004-9078-4.CrossRefPubMed Damiani A, Melgrati L, Franzoni G, Stepanyan M, Bonifacio S, Sesti F: Isobaric gasless laparoscopic myomectomy for removal of large uterine leiomyomas. Surg Endosc. 2006, 20: 1406-1409. 10.1007/s00464-004-9078-4.CrossRefPubMed
13.
go back to reference Sesti F, Capobianco F, Capozzolo T, Pietropolli A, Piccione E: Isobaric gasless laparoscopy versus minilaparotomy in uterine myomectomy: a randomized trial. Surg Endosc. 2008, 22: 917-923. 10.1007/s00464-007-9516-1.CrossRefPubMed Sesti F, Capobianco F, Capozzolo T, Pietropolli A, Piccione E: Isobaric gasless laparoscopy versus minilaparotomy in uterine myomectomy: a randomized trial. Surg Endosc. 2008, 22: 917-923. 10.1007/s00464-007-9516-1.CrossRefPubMed
Metadata
Title
Successful pregnancy outcome after laparoscopic-assisted excision of a bizarre leiomyoma: a case report
Authors
Akihiro Takeda
Sanae Imoto
Masahiko Mori
Hiromi Nakamura
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-5-344

Other articles of this Issue 1/2011

Journal of Medical Case Reports 1/2011 Go to the issue