Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 1/2011

01-01-2011 | Letter to the Editor

Successful pregnancy involving a man with chronic myeloid leukemia on dasatinib

Authors: Houssam Oweini, Zaher K. Otrock, Rami A. R. Mahfouz, Ali Bazarbachi

Published in: Archives of Gynecology and Obstetrics | Issue 1/2011

Login to get access

Abstract

Dasatinib is a highly potent Bcr-Abl inhibitor that is approved for the treatment of imatinib-resistant or -intolerant chronic myeloid leukemia (CML). The potential effects of dasatinib on sperm counts, sperm function, and fertility have not been studied yet. There is only one report in the medical literature of successful pregnancies while patients were taking dasatinib, thus making our case the second report. Here, we present the case of a 38-year-old man who conceived a healthy baby while on dasatinib therapy.
Literature
1.
2.
Deininger MW (2008) Milestones and monitoring in patients with CML treated with imatinib. Hematology Am Soc Hematol Educ Program 2008:419–426
3.
Ault P, Kantarjian H, O’Brien S, Faderl S, Beran M, Rios MB, Koller C, Giles F, Keating M, Talpaz M, Cortes J (2006) Pregnancy among patients with chronic myeloid leukemia treated with imatinib. J Clin Oncol 24:1204–1208CrossRefPubMed
4.
Lichtman M, Liesveld J (2001) Acute myelogenous leukemia. In: Beutler E, Lichtman M, Coller B et al (eds) Williams Hematology, edn 6. McGraw-Hill, New York, pp 1047–1084
5.
6.
Cortes J, O’Brien S, Ault P et al (2008) Pregnancy outcomes among patients with chronic myeloid leukemia treated with dasatinib. Blood 112 (abstr 3230)
Metadata
Title
Successful pregnancy involving a man with chronic myeloid leukemia on dasatinib
Authors
Houssam Oweini
Zaher K. Otrock
Rami A. R. Mahfouz
Ali Bazarbachi
Publication date
01-01-2011
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 1/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1501-6

Other articles of this Issue 1/2011

Archives of Gynecology and Obstetrics 1/2011 Go to the issue

Materno-fetal Medicine

A 30-year review of advanced abdominal pregnancy at the Mater Misericordiae Hospital, Afikpo, southeastern Nigeria (1976–2006)

Gynecologic Oncology

Cetuximab monotherapy in advanced cervical cancer: a retrospective study with five patients

Materno-fetal Medicine

“At fingers’ ends”: risk factors and perinatal outcome of pregnancies complicated by digital malformations

Materno-fetal Medicine

Effect of pre-pregnancy body mass index on adverse pregnancy outcome in north of China

Gynecologic Oncology

Treatment of recurrent vulvar Paget disease with imiquimod cream: a case report and review of the literature

Acknowledgement to Referees

Reviewers 2010