Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2011

Open Access 01-12-2011 | Case report

Successful management of aggressive fibromatosis of the neck using wide surgical excision: a case report

Authors: Zain A Sobani, Montasir Junaid, Mumtaz J Khan

Published in: Journal of Medical Case Reports | Issue 1/2011

Login to get access

Abstract

Introduction

Aggressive fibromatosis is a benign tumor, thought to arise from deep musculoaponeurotic structures, rarely found in the head or neck. However, when it does occur in the head and neck region, it tends to be more aggressive and associated with significant morbidity, which may be attributed to the vital vascular, neurological or anatomical structures in close proximity.

Case presentation

We report the case of a 39-year-old Pakistani man who presented with a two-month history of a lump on the right side of his neck. The mass was excised and histopathological analysis revealed a case of aggressive fibromatosis.

Conclusion

Due to the rarity of the condition no guidelines are available on the indications and extent of each modality. Due to its aggressive behavior and tendency to invade local structures and recur, a multi-modality management strategy is usually employed. On the basis of this case, we suggest that aggressive surgery is a viable management option and may be successfully used as a single modality treatment.
Appendix
Available only for authorised users
Literature
1.
go back to reference Sze H, Yeung MW: Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine. Hong Kong Med J. 2009, 15: 221-223.PubMed Sze H, Yeung MW: Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine. Hong Kong Med J. 2009, 15: 221-223.PubMed
2.
go back to reference Sharma A, Ngan BY, Sandor GK, Campisi P, Forte V: Pediatric aggressive fibromatosis of the head and neck: a 20-year retrospective review. J Pediatr Surg. 2008, 43: 1596-1604. 10.1016/j.jpedsurg.2008.02.001.CrossRefPubMed Sharma A, Ngan BY, Sandor GK, Campisi P, Forte V: Pediatric aggressive fibromatosis of the head and neck: a 20-year retrospective review. J Pediatr Surg. 2008, 43: 1596-1604. 10.1016/j.jpedsurg.2008.02.001.CrossRefPubMed
3.
go back to reference Kruse AL, Luebbers HT, Gratz KW, Obwegeser JA: Aggressive fibromatosis of the head and neck: a new classification based on a literature review over 40 years (1968-2008). Oral Maxillofac Surg. 2010, 14 (4): 227-232. 10.1007/s10006-010-0227-8.CrossRefPubMed Kruse AL, Luebbers HT, Gratz KW, Obwegeser JA: Aggressive fibromatosis of the head and neck: a new classification based on a literature review over 40 years (1968-2008). Oral Maxillofac Surg. 2010, 14 (4): 227-232. 10.1007/s10006-010-0227-8.CrossRefPubMed
4.
go back to reference El-Haddad M, El-Sebaie M, Ahmad R, Khalil E, Shahin M, Pant R, Memon M, Al-Hebshi A, Khafaga Y, Al-Shabanah M, Allam A: Treatment of aggressive fibromatosis: the experience of a single institution. Clin Oncol (R Coll Radiol). 2009, 21: 775-780.CrossRef El-Haddad M, El-Sebaie M, Ahmad R, Khalil E, Shahin M, Pant R, Memon M, Al-Hebshi A, Khafaga Y, Al-Shabanah M, Allam A: Treatment of aggressive fibromatosis: the experience of a single institution. Clin Oncol (R Coll Radiol). 2009, 21: 775-780.CrossRef
5.
go back to reference Hoos A, Lewis JJ, Urist MJ, Shaha AR, Hawkins WG, Shah JP, Brennan MF: Desmoid tumors of the head and neck--a clinical study of a rare entity. Head Neck. 2000, 22: 814-821. 10.1002/1097-0347(200012)22:8<814::AID-HED11>3.0.CO;2-#.CrossRefPubMed Hoos A, Lewis JJ, Urist MJ, Shaha AR, Hawkins WG, Shah JP, Brennan MF: Desmoid tumors of the head and neck--a clinical study of a rare entity. Head Neck. 2000, 22: 814-821. 10.1002/1097-0347(200012)22:8<814::AID-HED11>3.0.CO;2-#.CrossRefPubMed
6.
go back to reference Rudiger HA, Ngan SY, Ng M, Powell GJ, Choong PF: Radiation therapy in the treatment of desmoid tumours reduces surgical indications. Eur J Surg Oncol. 2010, 36: 84-88.CrossRefPubMed Rudiger HA, Ngan SY, Ng M, Powell GJ, Choong PF: Radiation therapy in the treatment of desmoid tumours reduces surgical indications. Eur J Surg Oncol. 2010, 36: 84-88.CrossRefPubMed
7.
go back to reference Park HC, Pyo HR, Shin KH, Suh CO: Radiation treatment for aggressive fibromatosis: findings from observed patterns of local failure. Oncology. 2003, 64: 346-352. 10.1159/000070292.CrossRefPubMed Park HC, Pyo HR, Shin KH, Suh CO: Radiation treatment for aggressive fibromatosis: findings from observed patterns of local failure. Oncology. 2003, 64: 346-352. 10.1159/000070292.CrossRefPubMed
8.
go back to reference Constantinidou A, Jones RL, Scurr M, Al-Muderis O, Judson I: Pegylated liposomal doxorubicin, an effective, well-tolerated treatment for refractory aggressive fibromatosis. Eur J Cancer. 2009, 45: 2930-2934. 10.1016/j.ejca.2009.08.016.CrossRefPubMed Constantinidou A, Jones RL, Scurr M, Al-Muderis O, Judson I: Pegylated liposomal doxorubicin, an effective, well-tolerated treatment for refractory aggressive fibromatosis. Eur J Cancer. 2009, 45: 2930-2934. 10.1016/j.ejca.2009.08.016.CrossRefPubMed
9.
go back to reference Nishida Y, Tsukushi S, Shido Y, Wasa J, Ishiguro N, Yamada Y: Successful treatment with meloxicam, a cyclooxygenase-2 inhibitor, of patients with extra-abdominal desmoid tumors: a pilot study. J Clin Oncol. 2010, 28: e107-109. 10.1200/JCO.2009.25.5950.CrossRefPubMed Nishida Y, Tsukushi S, Shido Y, Wasa J, Ishiguro N, Yamada Y: Successful treatment with meloxicam, a cyclooxygenase-2 inhibitor, of patients with extra-abdominal desmoid tumors: a pilot study. J Clin Oncol. 2010, 28: e107-109. 10.1200/JCO.2009.25.5950.CrossRefPubMed
10.
go back to reference Janinis J, Patriki M, Vini L, Aravantinos G, Whelan JS: The pharmacological treatment of aggressive fibromatosis: a systematic review. Ann Oncol. 2003, 14: 181-190. 10.1093/annonc/mdg064.CrossRefPubMed Janinis J, Patriki M, Vini L, Aravantinos G, Whelan JS: The pharmacological treatment of aggressive fibromatosis: a systematic review. Ann Oncol. 2003, 14: 181-190. 10.1093/annonc/mdg064.CrossRefPubMed
11.
go back to reference Chugh R, Chugh R, Wathen JK, Patel SR, Maki RG, Meyers PA, Schuetze SM, Priebat DA, Thomas DG, Jacobson JA, Samuels BL, Benjamin RS, Baker LH, Sarcoma Alliance for Research through Collaboration (SARC): Efficacy of imatinib in aggressive fibromatosis: results of a phase II multicenter Sarcoma Alliance for Research through Collaboration (SARC) trial. Clin Cancer Res. 2010, 16 (19): 4884-9481. 10.1158/1078-0432.CCR-10-1177.CrossRefPubMed Chugh R, Chugh R, Wathen JK, Patel SR, Maki RG, Meyers PA, Schuetze SM, Priebat DA, Thomas DG, Jacobson JA, Samuels BL, Benjamin RS, Baker LH, Sarcoma Alliance for Research through Collaboration (SARC): Efficacy of imatinib in aggressive fibromatosis: results of a phase II multicenter Sarcoma Alliance for Research through Collaboration (SARC) trial. Clin Cancer Res. 2010, 16 (19): 4884-9481. 10.1158/1078-0432.CCR-10-1177.CrossRefPubMed
12.
go back to reference Ilaslan H, Schils J, Joyce M, Marks K, Sundaram M: Radiofrequency ablation: another treatment option for local control of desmoid tumors. Skeletal Radiol. 2010, 39: 169-173. 10.1007/s00256-009-0807-6.CrossRefPubMed Ilaslan H, Schils J, Joyce M, Marks K, Sundaram M: Radiofrequency ablation: another treatment option for local control of desmoid tumors. Skeletal Radiol. 2010, 39: 169-173. 10.1007/s00256-009-0807-6.CrossRefPubMed
13.
go back to reference Kujak JL, Liu PT, Johnson GB, Callstrom MR: Early experience with percutaneous cryoablation of extra-abdominal desmoid tumors. Skeletal Radiol. 2010, 39: 175-182. 10.1007/s00256-009-0801-z.CrossRefPubMed Kujak JL, Liu PT, Johnson GB, Callstrom MR: Early experience with percutaneous cryoablation of extra-abdominal desmoid tumors. Skeletal Radiol. 2010, 39: 175-182. 10.1007/s00256-009-0801-z.CrossRefPubMed
Metadata
Title
Successful management of aggressive fibromatosis of the neck using wide surgical excision: a case report
Authors
Zain A Sobani
Montasir Junaid
Mumtaz J Khan
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-5-244

Other articles of this Issue 1/2011

Journal of Medical Case Reports 1/2011 Go to the issue