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Journal of Assisted Reproduction and Genetics

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01-06-2006 | Assisted Reproduction

Subclinical Pregnancy Losses Among Women Undergoing In-Vitro Fertilization With ICSI

Authors: Ulun Ulug, Suleyman Tosun, Esra Aksoy Jozwiak, Ali Mesut, Alper Sismanoglu, Mustafa Bahceci

Published in: Journal of Assisted Reproduction and Genetics | Issue 6/2006

Abstract

Background: The purpose of this study is to asses the frequency of subclinical pregnancy loss (SPL) among women undergoing controlled ovarian hyperstimulation (COH) and in-vitro fertilization with ICSI.

Methods: The study was retrospectively conducted in a private IVF center. SPL was defined by a temporary rise in serum βhCG, along with the absence of signs of intra- and extra-uterine pregnancy by transvaginal ultrasonography. Overall 5273 COH and ICSI cycles with embryo transfer (ET) were segregated according to serum E₂ levels percentiles (-24th, 25th, 74th, and 75th), women age and the type of spermatozoa for assisted fertilization (ejaculated and surgically retrieved). Those groups were assessed for SPL rates.

Results: Among the 3125 (59.25) conception cycles, 305 (9.7%) were diagnosed as SPL. There was no difference in SPL rate among E₂ percentile groups. Women older than 35 years of age had significantly higher rate of SPL compared to younger women. There was also no difference in SPL rate among pregnancies in whom surgically retrieved spermatozoa used or ejaculated spermatozoa used for assisted fertilization.

Conclusion: Our results demonstrated that SPL rate was not influenced by the levels of E₂ during COH or the origin of spermatozoa used for assisted fertilization. However, maternal age was found to be detrimental for SPL.

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Title: Subclinical Pregnancy Losses Among Women Undergoing In-Vitro Fertilization With ICSI
Authors: Ulun Ulug
Suleyman Tosun
Esra Aksoy Jozwiak
Ali Mesut
Alper Sismanoglu
Mustafa Bahceci
Publication date: 01-06-2006
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 6/2006
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-006-9038-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Subclinical Pregnancy Losses Among Women Undergoing In-Vitro Fertilization With ICSI

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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