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01-08-2004 | Original Article

Study on nerve fiber density in anterior vaginal epithelium for stress urinary incontinence

Authors: Lan Zhu, Jinghe Lang, Juan Chen, Jie Chen

Published in: International Urogynecology Journal | Issue 4/2004

Abstract

The aim of this study was to determine the relationship of innervation in anterior vaginal epithelium with the etiology of stress urinary incontinence (SUI). Fifty-three biopsy specimens of the anterior vaginal epithelium were obtained from 53 subjects in control, pelvic organ prolapse (POP) and SUI groups. Routine HE staining and immunohistochemical staining for protein gene product 9.5 (PGP9.5) were performed for all specimens. PGP9.5 immunoreactivity was identified in nerve fibers and cells of the epithelium and subepitheliual connective tissue of vagina. The nerve fiber profiles of vaginal epithelium in the SUI/POP groups were significantly lower than those in the control group (P<0.05). There was no correlation between the nerve fiber profiles and parity in SUI, POP and control groups. Decrease of nerve fiber profiles in anterior vaginal epithelium might lead to the occurrence of SUI.

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Title: Study on nerve fiber density in anterior vaginal epithelium for stress urinary incontinence
Authors: Lan Zhu
Jinghe Lang
Juan Chen
Jie Chen
Publication date: 01-08-2004
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 4/2004
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-004-1155-7

At a glance: The STEP trials

Springer Medicine

Study on nerve fiber density in anterior vaginal epithelium for stress urinary incontinence

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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