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Journal of Nuclear Cardiology

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01-02-2018 | History Corner

Studies on the velocity of blood flow

Authors: H. Strauss, MD, Barry Zaret, MD, Pierluigi Pieri, MD, Avijit Lahiri, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 1/2018

Excerpt

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Hermann Ludwig Blumgart, a 30-year-old physician,¹ working with a medical student, Otto C. Yens, performed the first radiotracer study in human subjects, to measure the velocity of blood flow. The studies were performed at the Thorndike Memorial Laboratory of Boston City Hospital.² The study described in this seminal manuscript highlight both the criteria for a clinically useful radiotracer, but also indicate the need to match instrumentation to the clinical measurements. …

Three years after performing these studies Hermann Blumgart was appointed Chairman of Medicine at the Beth Israel Hospital in Boston.

Blumgart HL, Yens OC. Studies on the velocity of blood flow: I. The method utilized. J Clin Invest. 1927;4:1-13.

Patton DD. The birth of Nuclear Medicine Instrumentation: Blumgart and Yens, 1925. J Nucl Med 2003;44:1362-5.

There was difficulty cannulating a vessel, resulting in frequent clotting. There was also a requirement for continuous sampling, which was difficult to control. Hence, the need for a noninvasive method that allowed continuous sampling.

Title: Studies on the velocity of blood flow
Authors: H. Strauss, MD
Barry Zaret, MD
Pierluigi Pieri, MD
Avijit Lahiri, MD, PhD
Publication date: 01-02-2018
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 1/2018
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-017-1130-6

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