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Open Access 20-11-2023 | Stroke | Original Communication

Safety and outcomes of different endovascular treatment techniques for anterior circulation ischaemic stroke in the elderly: data from the Imperial College Thrombectomy Registry

Authors: Lucio D’Anna, Lorenzo Barba, Matteo Foschi, Michele Romoli, Samir Abu-Rumeileh, Tsering Dolkar, Orsolya Vittay, Luke Dixon, Paul Bentley, Zoe Brown, Charles Hall, Omid Halse, Sohaa Jamil, Harri Jenkins, Dheeraj Kalladka, Joseph Kwan, Abid Malik, Maneesh Patel, Neil Rane, Dylan Roi, Abhinav Singh, Marius Venter, Soma Banerjee, Kyriakos Lobotesis

Published in: Journal of Neurology | Issue 3/2024

Abstract

Background

Although previous studies investigated the main predictors of outcomes after endovascular thrombectomy (EVT) in patients aged 80 years and older, less is known about the impact of the procedural features on outcomes in elderly patients. The aim of this study was to investigate the influence of EVT technical procedures on the main 3-month outcomes in a population of patients aged 80 years and older.

Methods

This observational, prospective, single-centre study included consecutive patients with acute LVO ischaemic stroke of the anterior circulation. The study outcomes were functional independence at 3 months after EVT (defined as a mRS score of 0–2), successful reperfusion (mTICI ≥ 2b), incidence of haeamorrhagic transformation, and 90-day all cause of mortality.

Results

Our cohort included 497 patients with acute ischaemic stroke due to LVO treated with EVT. Among them, 105 (21.1%) patients were aged ≥ 80 years. In the elderly group, multivariable regression analysis showed that thromboaspiration technique vs stent-retriever was the single independent predictor of favourable post-procedural TICI score (OR = 7.65, 95%CI = 2.22–26.32, p = 0.001).

Conclusions

Our study suggests that EVT for LVO stroke in the elderly could be safe. The use of thromboaspiration was associated with positive reperfusion outcome in this population. Further studies in larger series are warranted to confirm the present results and to evaluate the safety and efficacy of EVT in the elderly and oldest adults.

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Title: Safety and outcomes of different endovascular treatment techniques for anterior circulation ischaemic stroke in the elderly: data from the Imperial College Thrombectomy Registry
Authors: Lucio D’Anna
Lorenzo Barba
Matteo Foschi
Michele Romoli
Samir Abu-Rumeileh
Tsering Dolkar
Orsolya Vittay
Luke Dixon
Paul Bentley
Zoe Brown
Charles Hall
Omid Halse
Sohaa Jamil
Harri Jenkins
Dheeraj Kalladka
Joseph Kwan
Abid Malik
Maneesh Patel
Neil Rane
Dylan Roi
Abhinav Singh
Marius Venter
Soma Banerjee
Kyriakos Lobotesis
Publication date: 20-11-2023
Publisher: Springer Berlin Heidelberg
Keywords: Stroke
Thrombectomy
Published in: Journal of Neurology / Issue 3/2024
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-023-12077-3

2024 ASCO Annual Meeting

Springer Medicine

Safety and outcomes of different endovascular treatment techniques for anterior circulation ischaemic stroke in the elderly: data from the Imperial College Thrombectomy Registry

Abstract

Background

Methods

Results

Conclusions

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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