Skip to main content
Top
Published in: BMC Neurology 1/2022

Open Access 01-12-2022 | Stroke | Research

Cumulative experience improves the procedures of mechanical thrombectomy

Authors: Chengfang Liu, Yukai Liu, Zhongyuan Li, Pengyu Gong, Zhaohan Xu, Junshan Zhou, Weidong Zhang

Published in: BMC Neurology | Issue 1/2022

Login to get access

Abstract

Background

Mechanical thrombectomy has been widely performed for large vessel occlusion stroke. The present study aimed to determine whether cumulative experience could improve thrombectomy outcomes.

Methods

In this retrospective single-center analysis, patients who underwent mechanical thrombectomy with the Solitaire stent in 3 years from 25 April 2015 were enrolled in the current study. Patients’ characteristics, durations of admission and treatment, recanalization rates, clinical outcomes, and hemorrhage transformation rates were compared among the 3 years. Logistic analysis was used to analyze the independent correlation of the years and procedural outcomes.

Results

A total of 222 patients underwent mechanical thrombectomy in the 3 years: 50 in the first year, 68 in the second year, and 104 in the third year. Door-to-puncture time (P < 0.001) and puncture-to-recanalization time (P = 0.033) decreased significantly among the 3 years, while successful recanalization rates increased (P = 0.001). Logistic regression analysis showed an independent increase in the successful recanalization rates in the second year and third year (P = 0.020, P = 0.001) as compared to that in the first year.

Conclusions

Cumulative experience might improve the procedures of mechanical thrombectomy. The current findings suggested a potential benefit for centralization in the treatment of large vessel occlusion stroke.
Literature
1.
go back to reference Powers WJ, Derdeyn CP, Biller J, et al. American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2015;46(10):3020–35.CrossRef Powers WJ, Derdeyn CP, Biller J, et al. American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2015;46(10):3020–35.CrossRef
2.
go back to reference Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2018;49(3):e46–e110.CrossRef Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2018;49(3):e46–e110.CrossRef
3.
go back to reference Rinaldo L, Brinjikji W, Rabinstein AA. Transfer to High-Volume Centers Associated With Reduced Mortality After Endovascular Treatment of Acute Stroke. Stroke. 2017;48(5):1316–21.CrossRef Rinaldo L, Brinjikji W, Rabinstein AA. Transfer to High-Volume Centers Associated With Reduced Mortality After Endovascular Treatment of Acute Stroke. Stroke. 2017;48(5):1316–21.CrossRef
4.
go back to reference Nogueira RG, Haussen DC, Castonguay A, et al. Site Experience and Outcomes in the Trevo Acute Ischemic Stroke (TRACK) Multicenter Registry. Stroke. 2019;50:2455–60.CrossRef Nogueira RG, Haussen DC, Castonguay A, et al. Site Experience and Outcomes in the Trevo Acute Ischemic Stroke (TRACK) Multicenter Registry. Stroke. 2019;50:2455–60.CrossRef
5.
go back to reference El Nawar R, Lapergue B, Piotin M, et al. Higher Annual Operator Volume Is Associated With Better Reperfusion Rates in Stroke Patients Treated by Mechanical Thrombectomy: The ETIS Registry. JACC Cardiovasc Interv. 2019;12(4):385–91.CrossRef El Nawar R, Lapergue B, Piotin M, et al. Higher Annual Operator Volume Is Associated With Better Reperfusion Rates in Stroke Patients Treated by Mechanical Thrombectomy: The ETIS Registry. JACC Cardiovasc Interv. 2019;12(4):385–91.CrossRef
6.
go back to reference Pierot L, Jayaraman MV, Szikora I, et al. Standards of practice in acute ischemic stroke intervention: international recommendations. J Neurointerv Surg. 2018;10(11):1121–6.CrossRef Pierot L, Jayaraman MV, Szikora I, et al. Standards of practice in acute ischemic stroke intervention: international recommendations. J Neurointerv Surg. 2018;10(11):1121–6.CrossRef
7.
go back to reference Saber H, Navi BB, Grotta JC, et al. Real-World Treatment Trends in Endovascular Stroke Therapy. Stroke. 2019;50(3):683–9.CrossRef Saber H, Navi BB, Grotta JC, et al. Real-World Treatment Trends in Endovascular Stroke Therapy. Stroke. 2019;50(3):683–9.CrossRef
8.
go back to reference Sheth SA, Jahan R, Levy EI, et al. Rapid learning curve for Solitaire FR stent retriever therapy: evidence from roll-in and randomised patients in the SWIFT trial. J Neurointerv Surg. 2016;8(4):347–52.CrossRef Sheth SA, Jahan R, Levy EI, et al. Rapid learning curve for Solitaire FR stent retriever therapy: evidence from roll-in and randomised patients in the SWIFT trial. J Neurointerv Surg. 2016;8(4):347–52.CrossRef
9.
go back to reference Kim BM, Baek JH, Heo JH, et al. Effect of Cumulative Case Volume on Procedural and Clinical Outcomes in Endovascular Thrombectomy. Stroke. 2019;50(5):1178–83.CrossRef Kim BM, Baek JH, Heo JH, et al. Effect of Cumulative Case Volume on Procedural and Clinical Outcomes in Endovascular Thrombectomy. Stroke. 2019;50(5):1178–83.CrossRef
10.
go back to reference Zaidat OO, Yoo AJ, Khatri P, et al. Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke. 2013;44(9):2650–63.CrossRef Zaidat OO, Yoo AJ, Khatri P, et al. Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke. 2013;44(9):2650–63.CrossRef
11.
go back to reference Zaidat OO, Castonguay AC, Linfante I, et al. First Pass Effect: A New Measure for Stroke Thrombectomy Devices. Stroke. 2018;49(3):660–6.CrossRef Zaidat OO, Castonguay AC, Linfante I, et al. First Pass Effect: A New Measure for Stroke Thrombectomy Devices. Stroke. 2018;49(3):660–6.CrossRef
12.
go back to reference Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359(13):1317–29.CrossRef Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359(13):1317–29.CrossRef
13.
go back to reference Goyal M, Demchuk A, Menon B, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015;372(11):1019–30.CrossRef Goyal M, Demchuk A, Menon B, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015;372(11):1019–30.CrossRef
14.
go back to reference Albers G, Marks M, Kemp S, et al. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med. 2018;378(8):708–18.CrossRef Albers G, Marks M, Kemp S, et al. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med. 2018;378(8):708–18.CrossRef
15.
go back to reference Linfante I, Nogueira RG, Zaidat OO, et al. A joint statement from the Neurointerventional Societies: our position on operator experience and training for stroke thrombectomy. J Neurointerv Surg. 2019;11(6):533–4.CrossRef Linfante I, Nogueira RG, Zaidat OO, et al. A joint statement from the Neurointerventional Societies: our position on operator experience and training for stroke thrombectomy. J Neurointerv Surg. 2019;11(6):533–4.CrossRef
16.
go back to reference Fargen KM, Fiorella DJ, Mocco J. Practice makes perfect: establishing reasonable minimum thrombectomy volume requirements for stroke centers. J Neurointerv Surg. 2017;9(8):717–9.CrossRef Fargen KM, Fiorella DJ, Mocco J. Practice makes perfect: establishing reasonable minimum thrombectomy volume requirements for stroke centers. J Neurointerv Surg. 2017;9(8):717–9.CrossRef
17.
go back to reference Gupta R, Horev A, Nguyen T, et al. Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomes. J Neurointerv Surg. 2013;5(4):294–7.CrossRef Gupta R, Horev A, Nguyen T, et al. Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomes. J Neurointerv Surg. 2013;5(4):294–7.CrossRef
18.
go back to reference Adamczyk P, Attenello F, Wen G, et al. Mechanical thrombectomy in acute stroke: utilization variances and impact of procedural volume on inpatient mortality. J Stroke Cerebrovasc Dis. 2013;22(8):1263–9.CrossRef Adamczyk P, Attenello F, Wen G, et al. Mechanical thrombectomy in acute stroke: utilization variances and impact of procedural volume on inpatient mortality. J Stroke Cerebrovasc Dis. 2013;22(8):1263–9.CrossRef
19.
go back to reference Eesa M, Burns P, Almekhlafi M, et al. Mechanical thrombectomy with the Solitaire stent: is there a learning curve in achieving rapid recanalization times? J Neurointerv Surg. 2014;6(9):649–51.CrossRef Eesa M, Burns P, Almekhlafi M, et al. Mechanical thrombectomy with the Solitaire stent: is there a learning curve in achieving rapid recanalization times? J Neurointerv Surg. 2014;6(9):649–51.CrossRef
20.
go back to reference Weyland C, Hemmerich F, Möhlenbruch M, et al. Radiation exposure and fluoroscopy time in mechanical thrombectomy of anterior circulation ischemic stroke depending on the interventionalist's experience-a retrospective single center experience. Eur Radiol. 2020;30(3):1564–70.CrossRef Weyland C, Hemmerich F, Möhlenbruch M, et al. Radiation exposure and fluoroscopy time in mechanical thrombectomy of anterior circulation ischemic stroke depending on the interventionalist's experience-a retrospective single center experience. Eur Radiol. 2020;30(3):1564–70.CrossRef
21.
go back to reference Derdeyn C. The Powerful Benefit of Endovascular Thrombectomy for Acute Ischemic Stroke: Driving Major Changes in Stroke Systems of Care and Imaging Triage. Radiology. 2018;288(2):527–8.CrossRef Derdeyn C. The Powerful Benefit of Endovascular Thrombectomy for Acute Ischemic Stroke: Driving Major Changes in Stroke Systems of Care and Imaging Triage. Radiology. 2018;288(2):527–8.CrossRef
22.
go back to reference Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet (London, England). 2016;387(10029):1723–31.CrossRef Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet (London, England). 2016;387(10029):1723–31.CrossRef
23.
go back to reference Alegiani AC, Dorn F, Herzberg M, et al. Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. Int J Stroke. 2019;14(4):372–80.CrossRef Alegiani AC, Dorn F, Herzberg M, et al. Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. Int J Stroke. 2019;14(4):372–80.CrossRef
Metadata
Title
Cumulative experience improves the procedures of mechanical thrombectomy
Authors
Chengfang Liu
Yukai Liu
Zhongyuan Li
Pengyu Gong
Zhaohan Xu
Junshan Zhou
Weidong Zhang
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2022
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-022-02562-z

Other articles of this Issue 1/2022

BMC Neurology 1/2022 Go to the issue