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Journal of Neurology
Published in: Journal of Neurology 8/2023

Open Access 04-05-2023 | Stroke | Original Communication

Self-reported life-space mobility in the first year after ischemic stroke: longitudinal findings from the MOBITEC-Stroke project

Authors: Timo Hinrichs, Roland Rössler, Denis Infanger, Robert Weibel, Janine Schär, Eva-Maria Peters, Erja Portegijs, Taina Rantanen, Arno Schmidt-Trucksäss, Stefan T. Engelter, Nils Peters

Published in: Journal of Neurology | Issue 8/2023

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Abstract

Background

Life-space mobility is defined as the size of the area in which a person moves about within a specified period of time. Our study aimed to characterize life-space mobility, identify factors associated with its course, and detect typical trajectories in the first year after ischemic stroke.

Methods

MOBITEC-Stroke (ISRCTN85999967; 13/08/2020) was a cohort study with assessments performed 3, 6, 9 and 12 months after stroke onset. We applied linear mixed effects models (LMMs) with life-space mobility (Life-Space Assessment; LSA) as outcome and time point, sex, age, pre-stroke mobility limitation, stroke severity (National Institutes of Health Stroke Scale; NIHSS), modified Rankin Scale, comorbidities, neighborhood characteristics, availability of a car, Falls Efficacy Scale-International (FES-I), and lower extremity physical function (log-transformed timed up-and-go; TUG) as independent variables. We elucidated typical trajectories of LSA by latent class growth analysis (LCGA) and performed univariate tests for differences between classes.

Results

In 59 participants (mean age 71.6, SD 10.0 years; 33.9% women), mean LSA at 3 months was 69.3 (SD 27.3). LMMs revealed evidence (p ≤ 0.05) that pre-stroke mobility limitation, NIHSS, comorbidities, and FES-I were independently associated with the course of LSA; there was no evidence for a significant effect of time point. LCGA revealed three classes: “low stable”, “average stable”, and “high increasing”. Classes differed with regard to LSA starting value, pre-stroke mobility limitation, FES-I, and log-transformed TUG time.

Conclusion

Routinely assessing LSA starting value, pre-stroke mobility limitation, and FES-I may help clinicians identify patients at increased risk of failure to improve LSA.
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Metadata
Title
Self-reported life-space mobility in the first year after ischemic stroke: longitudinal findings from the MOBITEC-Stroke project
Authors
Timo Hinrichs
Roland Rössler
Denis Infanger
Robert Weibel
Janine Schär
Eva-Maria Peters
Erja Portegijs
Taina Rantanen
Arno Schmidt-Trucksäss
Stefan T. Engelter
Nils Peters
Publication date
04-05-2023
Publisher
Springer Berlin Heidelberg
Keyword
Stroke
Published in
Journal of Neurology / Issue 8/2023
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-023-11748-5

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