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Published in: Clinical Oral Investigations 6/2021

Open Access 01-06-2021 | Stroke | Original Article

Periodontitis related to cardiovascular events and mortality: a long-time longitudinal study

Authors: Viveca Wallin Bengtsson, Gösta Rutger Persson, Johan Sanmartin Berglund, Stefan Renvert

Published in: Clinical Oral Investigations | Issue 6/2021

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Abstract

Objective

The present study assessed if individuals ≥ 60 years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17 years.

Material and methods

At baseline individuals ≥ 60 received a dental examination including a panoramic radiograph. Periodontitis was defined as having ≥ 30% sites with ≥ 5-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered.

Results

Associations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up study in all individuals 60–93 years (HR: 1.5, CI: 1.1–2.1, p = 0.017), in women (HR: 2.1, CI: 1.3–3.4, p = 0.002), and in individuals 78–96 years (HR: 1.7, CI: 1.0–2.6, p = 0.033). Periodontitis was associated with mortality in all individuals (HR: 1.4, CI: 1.2–1.8, p = 0.002), specifically in men (HR: 1.5, CI: 1.1–1.9, p = 0.006) or in ages 60–72 years (HR: 2.2, CI: 1.5–3.2, p = 0.000). Periodontitis was more prevalent among men (OR: 1.8, CI: 1.3–2.4, p = 0.000).

Conclusions

Individuals with periodontitis have an increased risk for future events of ischemic heart diseases and death.

Clinical relevance

Improving periodontal health in older individuals may reduce overall mortality and ischemic heart diseases. Both dental and medical professionals should be aware of the associations and ultimately cooperate.
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Metadata
Title
Periodontitis related to cardiovascular events and mortality: a long-time longitudinal study
Authors
Viveca Wallin Bengtsson
Gösta Rutger Persson
Johan Sanmartin Berglund
Stefan Renvert
Publication date
01-06-2021
Publisher
Springer Berlin Heidelberg
Keyword
Stroke
Published in
Clinical Oral Investigations / Issue 6/2021
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-020-03739-x

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