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BMC Neurology

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Open Access 01-12-2022 | Stroke | Case report

Stroke in sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report

Authors: Ivana Markovic, Zoran Milenkovic, Bosanka Jocic-Jakubi, Amna Al Futaisi, Kakaria Anupam Kakaria, Yasser Walli

Published in: BMC Neurology | Issue 1/2022

Abstract

Background

Congenital absence of the internal carotid artery (ICA) is a highly infrequent congenital incidence and occurs in less than 0.01% of the population; bilateral absence is exceedingly rare, diagnosed below 10% of the unilateral absence of the ICA. Sickle cell disease (SCD) is a serious disorder and carries a high risk of stroke.

Case presentation

We present a five-year-old child with SCD who experienced an ischemic stroke episode with epileptic seizures. Neuroimaging revealed the agenesis of both ICAs. The frequency, embryology, and collateral pathway of the vascular anomaly as the clinical presentation, of this rare hematologic disease, are discussed.

Conclusions

Sickle cell disease (SCD) carries a high risk of stroke. Congenital absence of ICA occurs in less than 0.01% of the population; bilateral absence is diagnosed below 10% of the unilateral absence of the ICA.

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Title: Stroke in sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report
Authors: Ivana Markovic
Zoran Milenkovic
Bosanka Jocic-Jakubi
Amna Al Futaisi
Kakaria Anupam Kakaria
Yasser Walli
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Stroke
CT Angiography
Published in: BMC Neurology / Issue 1/2022
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-022-02702-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Stroke in sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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