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Published in: Journal of Clinical Monitoring and Computing 4/2020

Open Access 01-08-2020 | Stroke | Original Research

Cardiac output estimation using multi-beat analysis of the radial arterial blood pressure waveform: a method comparison study in patients having off-pump coronary artery bypass surgery using intermittent pulmonary artery thermodilution as the reference method

Authors: Bernd Saugel, Julia Heeschen, Alexander Hapfelmeier, Stefano Romagnoli, Gillis Greiwe

Published in: Journal of Clinical Monitoring and Computing | Issue 4/2020

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Abstract

Pulse wave analysis enables stroke volume to be estimated from an arterial blood pressure waveform. Multi-beat analysis is a novel pulse wave analysis method. We aimed to investigate cardiac output (CO) estimations using multi-beat analysis of the radial arterial blood pressure waveform in patients undergoing off-pump coronary artery bypass surgery (OPCAB) using intermittent pulmonary artery thermodilution (PATD) as the reference method. This was a prospective clinical method comparison study. In 58 patients, we measured CO using PATD (PATD-CO; reference method) and simultaneously recorded the radial arterial blood pressure waveform that we used for off-line estimation of CO based on multi-beat analysis (MBA-CO; test method) using the Argos CO monitor (Retia Medical; Valhalla, NY, USA). The final analysis was performed using 572 paired CO measurements. We performed Bland–Altman analysis accounting for multiple observations per patient. To describe the ability of the test method to track changes in CO over time we computed four-quadrant plots using a central exclusion zone of 15% and calculated the concordance rate. Mean PATD-CO was 4.13 ± 1.26 L/min and mean MBA-CO was 4.31 ± 1.25 L/min. The mean of the differences between PATD-CO and MBA-CO was − 0.20 L/min with a standard deviation of ± 1.14 L/min and 95% limits of agreement of − 2.48 to + 2.08 L/min. The concordance rate for CO changes between PATD-CO and MBA-CO was 89%. CO estimations using multi-beat analysis (Argos monitor) show reasonable agreement and trending ability compared with PATD-CO as the reference method in adult patients during OPCAB.
Literature
11.
12.
13.
go back to reference Bland JM, Altman DG. Calculating correlation coefficients with repeated observations: part 1—correlation within subjects. BMJ. 1995;310:446.CrossRef Bland JM, Altman DG. Calculating correlation coefficients with repeated observations: part 1—correlation within subjects. BMJ. 1995;310:446.CrossRef
15.
go back to reference Critchley LA, Critchley JA. A meta-analysis of studies using bias and precision statistics to compare cardiac output measurement techniques. J Clin Monit Cumput. 1999;15(2):85–91.CrossRef Critchley LA, Critchley JA. A meta-analysis of studies using bias and precision statistics to compare cardiac output measurement techniques. J Clin Monit Cumput. 1999;15(2):85–91.CrossRef
18.
go back to reference Segers P, Rietzschel ER, De Buyzere ML, Stergiopulos N, Westerhof N, Van Bortel LM, Gillebert T, Verdonck PR. Three- and four-element Windkessel models: assessment of their fitting performance in a large cohort of healthy middle-aged individuals. Proc Inst Mech Eng Part H J Eng Med. 2008;222(4):417–28. https://doi.org/10.1243/09544119jeim287.CrossRef Segers P, Rietzschel ER, De Buyzere ML, Stergiopulos N, Westerhof N, Van Bortel LM, Gillebert T, Verdonck PR. Three- and four-element Windkessel models: assessment of their fitting performance in a large cohort of healthy middle-aged individuals. Proc Inst Mech Eng Part H J Eng Med. 2008;222(4):417–28. https://​doi.​org/​10.​1243/​09544119jeim287.CrossRef
20.
go back to reference Frank O. The basic shape of the arterial pulse. First treatise: mathematical analysis. 1899. J Mol Cell Cardiol. 1990;22(3):255–77.CrossRef Frank O. The basic shape of the arterial pulse. First treatise: mathematical analysis. 1899. J Mol Cell Cardiol. 1990;22(3):255–77.CrossRef
22.
go back to reference Westerhof N, Elzinga G, Sipkema P. An artificial arterial system for pumping hearts. J Appl Physiol. 1971;31(5):776–81.CrossRef Westerhof N, Elzinga G, Sipkema P. An artificial arterial system for pumping hearts. J Appl Physiol. 1971;31(5):776–81.CrossRef
23.
go back to reference Burattini R, Gnudi G. Computer identification of models for the arterial tree input impedance: comparison between two new simple models and first experimental results. Med Biol Eng Comput. 1982;20(2):134–44.CrossRef Burattini R, Gnudi G. Computer identification of models for the arterial tree input impedance: comparison between two new simple models and first experimental results. Med Biol Eng Comput. 1982;20(2):134–44.CrossRef
24.
go back to reference Stergiopulos N, Westerhof BE, Westerhof N. Total arterial inertance as the fourth element of the windkessel model. Am J Physiol. 1999;276(1 Pt 2):H81–8.PubMed Stergiopulos N, Westerhof BE, Westerhof N. Total arterial inertance as the fourth element of the windkessel model. Am J Physiol. 1999;276(1 Pt 2):H81–8.PubMed
Metadata
Title
Cardiac output estimation using multi-beat analysis of the radial arterial blood pressure waveform: a method comparison study in patients having off-pump coronary artery bypass surgery using intermittent pulmonary artery thermodilution as the reference method
Authors
Bernd Saugel
Julia Heeschen
Alexander Hapfelmeier
Stefano Romagnoli
Gillis Greiwe
Publication date
01-08-2020
Publisher
Springer Netherlands
Keyword
Stroke
Published in
Journal of Clinical Monitoring and Computing / Issue 4/2020
Print ISSN: 1387-1307
Electronic ISSN: 1573-2614
DOI
https://doi.org/10.1007/s10877-019-00375-z

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