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Published in: Neurotherapeutics 3/2011

01-07-2011 | Review

Stroke Prevention-Surgical and Interventional Approaches to Carotid Stenosis

Authors: Kumar Rajamani, Seemant Chaturvedi

Published in: Neurotherapeutics | Issue 3/2011

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Abstract

Extracranial carotidartery stenosis is an important cause of stroke that often needs treatment with carotid revascularization. To prevent stroke recurrence, carotid endarterectomy has been well-established for many years in treating symptomatic high- and moderate-grade stenosis. Carotid stenting is an appealing, less invasive alternative to carotid endarterectomy, and several recent trials have compared the efficacy of the 2 procedures in patients with carotid stenosis. Carotid artery stenting has emerged as an important mode of therapy for high-risk patients with symtomatic high-grade stenosis. This review focuses on the current data available that will enable the clinician to decide optimal treatment strategies for patients with carotid stenosis.
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Literature
1.
go back to reference Fields WS, Maslenikov V, Meyer JS, Hass WK, Remington RD, Macdonald M. Joint study of extracranial arterial occlusion. V. Progress report of prognosis following surgery or nonsurgical treatment for transient cerebral ischemic attacks and cervical carotid artery lesions. JAMA 1970;211:1993–2003.PubMedCrossRef Fields WS, Maslenikov V, Meyer JS, Hass WK, Remington RD, Macdonald M. Joint study of extracranial arterial occlusion. V. Progress report of prognosis following surgery or nonsurgical treatment for transient cerebral ischemic attacks and cervical carotid artery lesions. JAMA 1970;211:1993–2003.PubMedCrossRef
2.
go back to reference Shaw DA, Venables GS, Cartlidge NE, Bates D, Dickinson PH. Carotid endarterectomy in patients with transient cerebral ischaemia. J NeurolSci 1984;64:45–53.CrossRef Shaw DA, Venables GS, Cartlidge NE, Bates D, Dickinson PH. Carotid endarterectomy in patients with transient cerebral ischaemia. J NeurolSci 1984;64:45–53.CrossRef
3.
go back to reference Collaborators NASCET. Beneficial effect of carotid endarterctomy in symptomatic patients with high grade stenosis. NEJM 1991;325:445–453.CrossRef Collaborators NASCET. Beneficial effect of carotid endarterctomy in symptomatic patients with high grade stenosis. NEJM 1991;325:445–453.CrossRef
4.
go back to reference ECSTTrialists’ Group. MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. European Carotid Surgery Trialists' Collaborative Group. Lancet 1991;337:1235–1243.CrossRef ECSTTrialists’ Group. MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. European Carotid Surgery Trialists' Collaborative Group. Lancet 1991;337:1235–1243.CrossRef
5.
go back to reference Mayberg MR, Wilson SE, Yatsu F, et al. Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis. Veterans Affairs Cooperative Studies Program 309 Trialist Group. JAMA 1991;266:3289–3294.PubMedCrossRef Mayberg MR, Wilson SE, Yatsu F, et al. Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis. Veterans Affairs Cooperative Studies Program 309 Trialist Group. JAMA 1991;266:3289–3294.PubMedCrossRef
6.
go back to reference Barnett HJM, Taylor DW, Eliasziw M, et al. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. N Engl J Med 1998;339:1415–1425.PubMedCrossRef Barnett HJM, Taylor DW, Eliasziw M, et al. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. N Engl J Med 1998;339:1415–1425.PubMedCrossRef
7.
go back to reference Rothwell PM, Eliasziw M, Gutnikov SA, et al. Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. The Lancet 2003;361:107.CrossRef Rothwell PM, Eliasziw M, Gutnikov SA, et al. Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. The Lancet 2003;361:107.CrossRef
8.
go back to reference Alamowitch S, Eliasziw M, Barnett HJM, for the North American Symptomatic Carotid Endarterectomy Trial and the ASAaCETG. The Risk and Benefit of Endarterectomy in Women With Symptomatic Internal Carotid Artery Disease. Stroke 2005;36:27–31.PubMedCrossRef Alamowitch S, Eliasziw M, Barnett HJM, for the North American Symptomatic Carotid Endarterectomy Trial and the ASAaCETG. The Risk and Benefit of Endarterectomy in Women With Symptomatic Internal Carotid Artery Disease. Stroke 2005;36:27–31.PubMedCrossRef
9.
go back to reference Rothwell PM, Gibson RJ, Slattery J, Sellar RJ, Warlow CP. Equivalence of measurements of carotid stenosis. A comparison of three methods on 1001 angiograms.European Carotid Surgery Trialists' Collaborative Group. Stroke 1994;25:2435–2439.PubMedCrossRef Rothwell PM, Gibson RJ, Slattery J, Sellar RJ, Warlow CP. Equivalence of measurements of carotid stenosis. A comparison of three methods on 1001 angiograms.European Carotid Surgery Trialists' Collaborative Group. Stroke 1994;25:2435–2439.PubMedCrossRef
10.
go back to reference Rothwell PM, Gutnikov SA, Warlow CP. Reanalysis of the final results of the European Carotid Surgery Trial. Stroke 2003;34:514–523.PubMedCrossRef Rothwell PM, Gutnikov SA, Warlow CP. Reanalysis of the final results of the European Carotid Surgery Trial. Stroke 2003;34:514–523.PubMedCrossRef
11.
go back to reference Jaff MR, Goldmakher GV, Lev MH, Romero JM. Imaging of the carotid arteries: the role of duplex ultrasonography, magnetic resonance arteriography, and computerized tomographic arteriography. Vasc Med 2008;13:281–292.PubMedCrossRef Jaff MR, Goldmakher GV, Lev MH, Romero JM. Imaging of the carotid arteries: the role of duplex ultrasonography, magnetic resonance arteriography, and computerized tomographic arteriography. Vasc Med 2008;13:281–292.PubMedCrossRef
12.
go back to reference Bernstein M, Fleming JF, Deck JH. Cerebral hyperperfusion after carotid endarterectomy: a cause of cerebral hemorrhage. Neurosurgery 1984;15:50–56.PubMedCrossRef Bernstein M, Fleming JF, Deck JH. Cerebral hyperperfusion after carotid endarterectomy: a cause of cerebral hemorrhage. Neurosurgery 1984;15:50–56.PubMedCrossRef
13.
go back to reference Piepgras DG, Morgan MK, Sundt TM Jr., Yanagihara T, Mussman LM. Intracerebral hemorrhage after carotid endarterectomy. J Neurosurg 1988;68:532–536.PubMedCrossRef Piepgras DG, Morgan MK, Sundt TM Jr., Yanagihara T, Mussman LM. Intracerebral hemorrhage after carotid endarterectomy. J Neurosurg 1988;68:532–536.PubMedCrossRef
14.
go back to reference Ferguson GG, Eliasziw M, Barr HWK, et al. The North American Symptomatic Carotid Endarterectomy Trial: surgical results in 1415 patients. Stroke 1999;30:1751–1758.PubMedCrossRef Ferguson GG, Eliasziw M, Barr HWK, et al. The North American Symptomatic Carotid Endarterectomy Trial: surgical results in 1415 patients. Stroke 1999;30:1751–1758.PubMedCrossRef
15.
go back to reference Hafner DH, Smith RB 3 rd, King OW, et al. Massive intracerebral hemorrhage following carotid endarterectomy. Arch Surg 1987;122:305–307.PubMed Hafner DH, Smith RB 3 rd, King OW, et al. Massive intracerebral hemorrhage following carotid endarterectomy. Arch Surg 1987;122:305–307.PubMed
16.
go back to reference Lovett JK, Coull AJ, Rothwell PM. Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies. Neurology 2004;62:569–573.PubMed Lovett JK, Coull AJ, Rothwell PM. Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies. Neurology 2004;62:569–573.PubMed
17.
go back to reference Johnston SC, Gress DR, Browner WS, Sidney S. Short-term prognosis after emergency department diagnosis of TIA. JAMA 2000;284:2901–2906.PubMedCrossRef Johnston SC, Gress DR, Browner WS, Sidney S. Short-term prognosis after emergency department diagnosis of TIA. JAMA 2000;284:2901–2906.PubMedCrossRef
18.
go back to reference Rothwell PM, Eliasziw M, Gutnikov SA, Warlow CP, Barnett HJM. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. The Lancet 2004;363:915.CrossRef Rothwell PM, Eliasziw M, Gutnikov SA, Warlow CP, Barnett HJM. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. The Lancet 2004;363:915.CrossRef
19.
go back to reference Chaturvedi S, Bruno A, Feasby T, et al. Carotid endarterectomy — an evidence-based review: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2005;65:794–801.PubMedCrossRef Chaturvedi S, Bruno A, Feasby T, et al. Carotid endarterectomy — an evidence-based review: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2005;65:794–801.PubMedCrossRef
20.
go back to reference Sacco RL, Adams R, Albers G, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: astatement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline. Stroke 2006;37:577–617.PubMedCrossRef Sacco RL, Adams R, Albers G, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: astatement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline. Stroke 2006;37:577–617.PubMedCrossRef
21.
go back to reference Bond R, Rerkasem K, Cuffe R, Rothwell PM. A Systematic review of the associations between age and sex and the operative risks of carotid endarterectomy.CerebrovascDis 2005;20:69–77.PubMedCrossRef Bond R, Rerkasem K, Cuffe R, Rothwell PM. A Systematic review of the associations between age and sex and the operative risks of carotid endarterectomy.CerebrovascDis 2005;20:69–77.PubMedCrossRef
22.
go back to reference Grego F, Lepidi S, Antonello M, et al. Is carotid endarterectomy in octogenarians more dangerous than in younger patients? J CardiovascSurg (Torino) 2005;46:477–483. Grego F, Lepidi S, Antonello M, et al. Is carotid endarterectomy in octogenarians more dangerous than in younger patients? J CardiovascSurg (Torino) 2005;46:477–483.
23.
go back to reference Wennberg DE, Lucas FL, Birkmeyer JD, Bredenberg CE, Fisher ES. Variation in carotid endarterectomy mortality in the Medicare population: trial hospitals, volume, and patient characteristics. JAMA 1998;279:1278–1281.PubMedCrossRef Wennberg DE, Lucas FL, Birkmeyer JD, Bredenberg CE, Fisher ES. Variation in carotid endarterectomy mortality in the Medicare population: trial hospitals, volume, and patient characteristics. JAMA 1998;279:1278–1281.PubMedCrossRef
24.
go back to reference Benavente O, Eliasziw M, Streifler JY, et al. Prognosis after transient monocular blindness associated with carotid-artery stenosis. N Engl J Med 2001;345:1084–1090.PubMedCrossRef Benavente O, Eliasziw M, Streifler JY, et al. Prognosis after transient monocular blindness associated with carotid-artery stenosis. N Engl J Med 2001;345:1084–1090.PubMedCrossRef
25.
go back to reference Grego F, Antonello M, Lepidi S, et al. Is contralateral carotid artery occlusion a risk factor for carotid endarterectomy? Ann VascSurg 2005;19:882–889.PubMedCrossRef Grego F, Antonello M, Lepidi S, et al. Is contralateral carotid artery occlusion a risk factor for carotid endarterectomy? Ann VascSurg 2005;19:882–889.PubMedCrossRef
26.
go back to reference AbuRahma AF, Robinson P, Holt SM, Herzog TA, Mowery NT. Perioperative and late stroke rates of carotid endarterectomy contralateral to carotid artery occlusion: results from a randomized trial. Stroke 2000;31:1566–1571.PubMedCrossRef AbuRahma AF, Robinson P, Holt SM, Herzog TA, Mowery NT. Perioperative and late stroke rates of carotid endarterectomy contralateral to carotid artery occlusion: results from a randomized trial. Stroke 2000;31:1566–1571.PubMedCrossRef
27.
go back to reference Klijn CJ, van Buren PA, Kappelle LJ, et al. Outcome in patients with symptomatic occlusion of the internal carotid artery. Eur J VascEndovascSurg 2000;19:579–586.PubMedCrossRef Klijn CJ, van Buren PA, Kappelle LJ, et al. Outcome in patients with symptomatic occlusion of the internal carotid artery. Eur J VascEndovascSurg 2000;19:579–586.PubMedCrossRef
28.
go back to reference Gasecki AP, Eliasziw M, Ferguson GG, Hachinski V, Barnett HJM. Long-term prognosis and effect of endarterectomy in patients with symptomatic severe carotid stenosis and contralateral carotid stenosis or occlusion: results from NASCET. JNeurosurg 1995;83:778.PubMedCrossRef Gasecki AP, Eliasziw M, Ferguson GG, Hachinski V, Barnett HJM. Long-term prognosis and effect of endarterectomy in patients with symptomatic severe carotid stenosis and contralateral carotid stenosis or occlusion: results from NASCET. JNeurosurg 1995;83:778.PubMedCrossRef
29.
go back to reference Park AE, McCarthy WJ, Pearce WH, Matsumura JS, Yao JS. Carotid plaque morphology correlates with presenting symptomatology. J VascSurg 1998;27:872–879.PubMedCrossRef Park AE, McCarthy WJ, Pearce WH, Matsumura JS, Yao JS. Carotid plaque morphology correlates with presenting symptomatology. J VascSurg 1998;27:872–879.PubMedCrossRef
30.
go back to reference Fisher M, Paganini-Hill A, Martin A, et al. Carotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis. Stroke 2005;36:253–257.PubMedCrossRef Fisher M, Paganini-Hill A, Martin A, et al. Carotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis. Stroke 2005;36:253–257.PubMedCrossRef
31.
go back to reference Eliasziw M, Streifler JY, Fox AJ, Hachinski VC, Ferguson GG, Barnett HJ. Significance of plaque ulceration in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial. Stroke 1994;25:304–308.PubMedCrossRef Eliasziw M, Streifler JY, Fox AJ, Hachinski VC, Ferguson GG, Barnett HJ. Significance of plaque ulceration in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial. Stroke 1994;25:304–308.PubMedCrossRef
32.
go back to reference Streifler JY, Eliasziw M, Fox AJ, et al. Angiographic detection of carotid plaque ulceration. Comparison with surgical observations in a multicenter study.North American Symptomatic Carotid Endarterectomy Trial. Stroke 1994;25:1130–1132.PubMedCrossRef Streifler JY, Eliasziw M, Fox AJ, et al. Angiographic detection of carotid plaque ulceration. Comparison with surgical observations in a multicenter study.North American Symptomatic Carotid Endarterectomy Trial. Stroke 1994;25:1130–1132.PubMedCrossRef
33.
go back to reference Tartari S, Rizzati R, Righi R, et al. High-resolution MRI of carotid plaque with a neurovascular coil and contrast-enhanced MR angiography: one-stop shopping for the comprehensive assessment of carotid atherosclerosis. Am J Roentgenol 2011;196:1164–1171.CrossRef Tartari S, Rizzati R, Righi R, et al. High-resolution MRI of carotid plaque with a neurovascular coil and contrast-enhanced MR angiography: one-stop shopping for the comprehensive assessment of carotid atherosclerosis. Am J Roentgenol 2011;196:1164–1171.CrossRef
34.
go back to reference Takaya N, Yuan C, Chu B, et al. Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI—initial results. Stroke 2006;37:818–823.PubMedCrossRef Takaya N, Yuan C, Chu B, et al. Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI—initial results. Stroke 2006;37:818–823.PubMedCrossRef
35.
go back to reference Morgenstern LB, Fox AJ, Sharpe BL, Eliasziw M, Barnett HJ, Grotta JC. The risks and benefits of carotid endarterectomy in patients with near occlusion of the carotid artery.North American Symptomatic Carotid Endarterectomy Trial (NASCET) Group. Neurology 1997;48:911–915.PubMed Morgenstern LB, Fox AJ, Sharpe BL, Eliasziw M, Barnett HJ, Grotta JC. The risks and benefits of carotid endarterectomy in patients with near occlusion of the carotid artery.North American Symptomatic Carotid Endarterectomy Trial (NASCET) Group. Neurology 1997;48:911–915.PubMed
36.
go back to reference Fox AJ, Eliasziw M, Rothwell PM, et al. Identification, prognosis, and management of patients with carotid artery near occlusion. AJNR Am J Neuroradiol 2005;26:2086–2094.PubMed Fox AJ, Eliasziw M, Rothwell PM, et al. Identification, prognosis, and management of patients with carotid artery near occlusion. AJNR Am J Neuroradiol 2005;26:2086–2094.PubMed
37.
go back to reference Hobson R, Weiss D, Fields W, Goldstone J, et al. Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA 1995;273:1421–1428.CrossRef Hobson R, Weiss D, Fields W, Goldstone J, et al. Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA 1995;273:1421–1428.CrossRef
38.
go back to reference MRC Asymptomatic Carotid Surgery Trial Collaborative Group (2004) Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. The Lancet. 363:1491–1502.CrossRef MRC Asymptomatic Carotid Surgery Trial Collaborative Group (2004) Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. The Lancet. 363:1491–1502.CrossRef
39.
go back to reference Tu JV, Wang H, Bowyer B, Green L, Fang J, Kucey D. Risk factors for death or stroke after carotid endarterectomy: observations from the Ontario Carotid Endarterectomy Registry. Stroke 2003;34:2568–2573.PubMedCrossRef Tu JV, Wang H, Bowyer B, Green L, Fang J, Kucey D. Risk factors for death or stroke after carotid endarterectomy: observations from the Ontario Carotid Endarterectomy Registry. Stroke 2003;34:2568–2573.PubMedCrossRef
40.
go back to reference Halliday A, Harrison M, Hayter E, et al. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentrerandomised trial. The Lancet 2010;376:1074–1084.CrossRef Halliday A, Harrison M, Hayter E, et al. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentrerandomised trial. The Lancet 2010;376:1074–1084.CrossRef
41.
go back to reference Chambers BR, Donnan GA. Carotid endarterectomy for asymptomatic carotid stenosis. Cochrane Database Syst Rev 2005:CD001923. Chambers BR, Donnan GA. Carotid endarterectomy for asymptomatic carotid stenosis. Cochrane Database Syst Rev 2005:CD001923.
42.
go back to reference Barnett HJM, Meldrum HE, Eliasziw M. The appropriate use of carotid endarterectomy. CMAJ 2002;166:1169–1179.PubMed Barnett HJM, Meldrum HE, Eliasziw M. The appropriate use of carotid endarterectomy. CMAJ 2002;166:1169–1179.PubMed
43.
go back to reference Inzitari D, Eliasziw M, Gates P, et al. The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis. NEJM 2000;342:1693–1701. Inzitari D, Eliasziw M, Gates P, et al. The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis. NEJM 2000;342:1693–1701.
44.
go back to reference Goldstein LB, Samsa GP, Matchar DB, Oddone EZ. Multicenter review of preoperative risk factors for endarterectomy for asymptomatic carotid artery stenosis. Stroke 1998;29:750–753.PubMedCrossRef Goldstein LB, Samsa GP, Matchar DB, Oddone EZ. Multicenter review of preoperative risk factors for endarterectomy for asymptomatic carotid artery stenosis. Stroke 1998;29:750–753.PubMedCrossRef
45.
go back to reference Abbott AL. Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: results of a systematic review and analysis. Stroke 2009;40:e573-e583.PubMedCrossRef Abbott AL. Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: results of a systematic review and analysis. Stroke 2009;40:e573-e583.PubMedCrossRef
46.
go back to reference Spence JD, Tamayo A, Lownie SP, Ng WP, Ferguson GG. Absence of microemboli on transcranial doppler identifies low-risk patients with asymptomatic carotid stenosis. Stroke 2005;36:2373–2378.PubMedCrossRef Spence JD, Tamayo A, Lownie SP, Ng WP, Ferguson GG. Absence of microemboli on transcranial doppler identifies low-risk patients with asymptomatic carotid stenosis. Stroke 2005;36:2373–2378.PubMedCrossRef
47.
go back to reference Spence JD, Coates V, Li H, et al. Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis. Arch Neurol 2010;67:180–186.PubMedCrossRef Spence JD, Coates V, Li H, et al. Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis. Arch Neurol 2010;67:180–186.PubMedCrossRef
48.
go back to reference Goldstein LB, Adams R, Alberts MJ, et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline. Circulation 2006;113:1583–1633. Goldstein LB, Adams R, Alberts MJ, et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline. Circulation 2006;113:1583–1633.
49.
go back to reference Taylor DW, Barnett HJM, Haynes RB, et al. Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial. The Lancet 1999;353:2179–2184.CrossRef Taylor DW, Barnett HJM, Haynes RB, et al. Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial. The Lancet 1999;353:2179–2184.CrossRef
50.
go back to reference Engelter S, Lyrer P. Antiplatelet therapy for preventing stroke and other vascular events after carotid endarterectomy. Cochrane Database Syst Rev 2003:CD001458. Engelter S, Lyrer P. Antiplatelet therapy for preventing stroke and other vascular events after carotid endarterectomy. Cochrane Database Syst Rev 2003:CD001458.
51.
go back to reference Poldermans D, Bax JJ, Kertai MD, et al. Statins are associated with a reduced incidence of perioperative mortality in patients undergoing major noncardiac vascular surgery. Circulation 2003;107:1848–1851.PubMedCrossRef Poldermans D, Bax JJ, Kertai MD, et al. Statins are associated with a reduced incidence of perioperative mortality in patients undergoing major noncardiac vascular surgery. Circulation 2003;107:1848–1851.PubMedCrossRef
52.
go back to reference Devereaux PJ, Beattie WS, Choi PTL, et al. How strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials. BMJ 2005;331:313–321.PubMedCrossRef Devereaux PJ, Beattie WS, Choi PTL, et al. How strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials. BMJ 2005;331:313–321.PubMedCrossRef
53.
go back to reference McGirt MJ, Perler BA, Brooke BS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors reduce the risk of perioperative stroke and mortality after carotid endarterectomy. JVascSurg 2005;42:829–836.PubMedCrossRef McGirt MJ, Perler BA, Brooke BS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors reduce the risk of perioperative stroke and mortality after carotid endarterectomy. JVascSurg 2005;42:829–836.PubMedCrossRef
54.
go back to reference Perler BA, Murphy K, Sternbach Y, Gailloud P, Shake JG. Immediate postoperative thrombolytic therapy: an aggressive strategy for neurologic salvage when cerebral thromboembolism complicates carotid endarterectomy. J VascSurg 2000;31:1033–1037.PubMedCrossRef Perler BA, Murphy K, Sternbach Y, Gailloud P, Shake JG. Immediate postoperative thrombolytic therapy: an aggressive strategy for neurologic salvage when cerebral thromboembolism complicates carotid endarterectomy. J VascSurg 2000;31:1033–1037.PubMedCrossRef
55.
go back to reference Anzuini A, Briguori C, Roubin GS, et al. Emergency stenting to treat neurological complications occurring after carotid endarterectomy. J AmCollCardiol 2001;37:2074–2079.PubMedCrossRef Anzuini A, Briguori C, Roubin GS, et al. Emergency stenting to treat neurological complications occurring after carotid endarterectomy. J AmCollCardiol 2001;37:2074–2079.PubMedCrossRef
56.
go back to reference Findlay JM, Marchak BE. Reoperation for acute hemispheric stroke after carotid endarterectomy: is there any value? Neurosurgery 2002;50:486-492.PubMed Findlay JM, Marchak BE. Reoperation for acute hemispheric stroke after carotid endarterectomy: is there any value? Neurosurgery 2002;50:486-492.PubMed
57.
go back to reference van Mook WN, Rennenberg RJ, Schurink GW, et al. Cerebral hyperperfusion syndrome. Lancet Neurol 2005;4:877–888.PubMedCrossRef van Mook WN, Rennenberg RJ, Schurink GW, et al. Cerebral hyperperfusion syndrome. Lancet Neurol 2005;4:877–888.PubMedCrossRef
58.
go back to reference Rothwell PM, Slattery J, Warlow CP. Clinical and angiographic predictors of stroke and death from carotid endarterectomy: systematic review. BMJ 1997;315:1571–1577.PubMed Rothwell PM, Slattery J, Warlow CP. Clinical and angiographic predictors of stroke and death from carotid endarterectomy: systematic review. BMJ 1997;315:1571–1577.PubMed
59.
go back to reference AbuRahma AF, Jennings TG, Wulu JT, Tarakji L, Robinson PA. Redo carotid endarterectomy versus primary carotid endarterectomy. Stroke 2001;32:2787–2792.PubMedCrossRef AbuRahma AF, Jennings TG, Wulu JT, Tarakji L, Robinson PA. Redo carotid endarterectomy versus primary carotid endarterectomy. Stroke 2001;32:2787–2792.PubMedCrossRef
60.
go back to reference Metzger DC. Embolic protection in carotid artery stenting: new options. TechVascIntervRadiol 2011;14:86–94.PubMedCrossRef Metzger DC. Embolic protection in carotid artery stenting: new options. TechVascIntervRadiol 2011;14:86–94.PubMedCrossRef
61.
go back to reference Bates ER, Babb JD, Casey DE, et al. ACCF/SCAI/SVMB/SIR/ASITN 2007 clinical expert consensus document on carotid stenting. J Am CollCardiol 2007;49:126–170.PubMedCrossRef Bates ER, Babb JD, Casey DE, et al. ACCF/SCAI/SVMB/SIR/ASITN 2007 clinical expert consensus document on carotid stenting. J Am CollCardiol 2007;49:126–170.PubMedCrossRef
62.
go back to reference Yadav JS, Wholey MH, Kuntz RE, et al. Protected carotid-artery stenting versus endarterectomy in high-risk patients. N Engl J Med 2004;351:1493–1501.PubMedCrossRef Yadav JS, Wholey MH, Kuntz RE, et al. Protected carotid-artery stenting versus endarterectomy in high-risk patients. N Engl J Med 2004;351:1493–1501.PubMedCrossRef
63.
go back to reference Gurm HS, Yadav JS, Fayad P, et al. Long-term results of carotid stenting versus endarterectomy in high-risk patients. NEJM 2008;358:1572–1579. Gurm HS, Yadav JS, Fayad P, et al. Long-term results of carotid stenting versus endarterectomy in high-risk patients. NEJM 2008;358:1572–1579.
64.
go back to reference Goodney PP, Powell RJ. Carotid artery stenting: what have we learned from the clinical trials and registries and where do we go from here. Ann Vasc Surg 2008;22:148–158.PubMedCrossRef Goodney PP, Powell RJ. Carotid artery stenting: what have we learned from the clinical trials and registries and where do we go from here. Ann Vasc Surg 2008;22:148–158.PubMedCrossRef
65.
go back to reference SPACE, Collaborative Group. 30 day results from the SPACE trial of stent-protected angioplasty versus carotid endarterectomy in symptomatic patients: a randomised non-inferiority trial. The Lancet 2006;368:1239–1247. SPACE, Collaborative Group. 30 day results from the SPACE trial of stent-protected angioplasty versus carotid endarterectomy in symptomatic patients: a randomised non-inferiority trial. The Lancet 2006;368:1239–1247.
66.
go back to reference Eckstein H-H, Ringleb P, Allenberg J-R, et al. Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial. The Lancet Neurology 2008;7:893–902.CrossRef Eckstein H-H, Ringleb P, Allenberg J-R, et al. Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial. The Lancet Neurology 2008;7:893–902.CrossRef
67.
go back to reference Mas J-L, Chatellier G, Beyssen B, et al. Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis. N Engl J Med 2006;355:1660–1671.PubMedCrossRef Mas J-L, Chatellier G, Beyssen B, et al. Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis. N Engl J Med 2006;355:1660–1671.PubMedCrossRef
68.
go back to reference Gray WA, Rosenfield KA, Jaff MR, Chaturvedi S, Peng L, Verta P. Influence of site and operator characteristics on carotid artery stent outcomes: analysis of the CAPTURE 2 (Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare Events) Clinical Study. JACCCardiovascInterv 2011;4:235–246.PubMedCrossRef Gray WA, Rosenfield KA, Jaff MR, Chaturvedi S, Peng L, Verta P. Influence of site and operator characteristics on carotid artery stent outcomes: analysis of the CAPTURE 2 (Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare Events) Clinical Study. JACCCardiovascInterv 2011;4:235–246.PubMedCrossRef
69.
go back to reference Harjai KJ, Mehta RH. Trials and tribulations of carotid artery stenting: the interventionalists' perspective on SAPPHIRE, EVA-3S, and SPACE trials. J IntervCardiol 2007;20:389–394.PubMedCrossRef Harjai KJ, Mehta RH. Trials and tribulations of carotid artery stenting: the interventionalists' perspective on SAPPHIRE, EVA-3S, and SPACE trials. J IntervCardiol 2007;20:389–394.PubMedCrossRef
70.
go back to reference Howard VJ, Lutsep HL, Mackey A, et al. Influence of sex on outcomes of stenting versus endarterectomy: a subgroup analysis of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). The Lancet Neurol 2011;10:530–537. Howard VJ, Lutsep HL, Mackey A, et al. Influence of sex on outcomes of stenting versus endarterectomy: a subgroup analysis of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). The Lancet Neurol 2011;10:530–537.
71.
go back to reference Economopoulos KP, Sergentanis TN, Tsivgoulis G, Mariolis AD, Stefanadis C. Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes. Stroke 2011;42:687–692.PubMedCrossRef Economopoulos KP, Sergentanis TN, Tsivgoulis G, Mariolis AD, Stefanadis C. Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes. Stroke 2011;42:687–692.PubMedCrossRef
72.
go back to reference Bangalore S, Kumar S, Wetterslev J, et al. Carotid artery stenting vs carotid endarterectomy: meta-analysis and diversity-adjusted trial sequential analysis of randomized trials. Arch Neurol 2011;68:172–184. Bangalore S, Kumar S, Wetterslev J, et al. Carotid artery stenting vs carotid endarterectomy: meta-analysis and diversity-adjusted trial sequential analysis of randomized trials. Arch Neurol 2011;68:172–184.
Metadata
Title
Stroke Prevention-Surgical and Interventional Approaches to Carotid Stenosis
Authors
Kumar Rajamani
Seemant Chaturvedi
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Neurotherapeutics / Issue 3/2011
Print ISSN: 1933-7213
Electronic ISSN: 1878-7479
DOI
https://doi.org/10.1007/s13311-011-0052-2

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