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Published in: Journal of Gastrointestinal Surgery 5/2015

01-05-2015 | Original Article

Strictureplasty for Treatment of Crohn’s Disease: an ACS-NSQIP Database Analysis

Authors: Cristina B. Geltzeiler, J. Isaac Young, Brian S. Diggs, Kian Keyashian, Karen Deveney, Kim C. Lu, V. Liana Tsikitis, Daniel O. Herzig

Published in: Journal of Gastrointestinal Surgery | Issue 5/2015

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Abstract

Introduction

Strictureplasty is an alternative to resection for treatment of Crohn’s disease (CD) strictures. It preserves bowel length, and specialized centers report favorable outcomes. Strictureplasty rates, however, are thought to be low, and it was recently removed from required cases for colon and rectal surgery residents. We examined operative characteristics, and trends in its use using a large national database.

Materials and Methods

We examined the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2005 to 2012, identifying patients with CD who underwent strictureplasty. We identified patient characteristics, outcome variables, and trends in utilization of strictureplasty.

Results

A total of 9172 patients underwent surgery for CD. Two hundred fifty-six (2.8 %) underwent strictureplasty. Median preoperative albumin was 3.6. Preoperative steroid use and weight loss rates were 39 and 8 %. Rates of wound infection and organ space infection were 11 and 4 %. Rate of reoperation was 6 %. Outcomes did not change significantly over time (all p = NS). The proportion of CD operations that included a strictureplasty decreased from 5.1 to 1.7 % (OR 0.902 with each additional year, 95 % CI (0.852, 0.960), p < 0.001).

Conclusion

Strictureplasty as treatment for CD is decreasing in the ACS-NSQIP database. Infectious complications and reoperation rates following strictureplasty are low and have not changed over time.
Literature
1.
go back to reference Yamamoto T, Fazio VW, Tekkis PP. Safety and efficacy of strictureplasty for Crohn's disease: a systematic review and meta-analysis. Dis Colon and Rectum 2007; 50:1968-86.CrossRef Yamamoto T, Fazio VW, Tekkis PP. Safety and efficacy of strictureplasty for Crohn's disease: a systematic review and meta-analysis. Dis Colon and Rectum 2007; 50:1968-86.CrossRef
2.
go back to reference Dietz DW, Fazio VW, Laureti S, Strong SA, Hull TL, Church J, Renzi FH, Lavery IC, Senagore AJ. Strictureplasty in diffuse Crohn's jejunoileitis: safe and durable. Dis Colon and Rectum 2002;45:764-70.CrossRef Dietz DW, Fazio VW, Laureti S, Strong SA, Hull TL, Church J, Renzi FH, Lavery IC, Senagore AJ. Strictureplasty in diffuse Crohn's jejunoileitis: safe and durable. Dis Colon and Rectum 2002;45:764-70.CrossRef
3.
go back to reference Michelassi F, Hurst RD, Melis M, Rubin M, Cohen R, Gasparitis A, Hanauer SB, Hart J. Side-to-side isoperistaltic strictureplasty in extensive Crohn's disease: a prospective longitudinal study. Ann Surg 2000;232:401-8.CrossRefPubMedCentralPubMed Michelassi F, Hurst RD, Melis M, Rubin M, Cohen R, Gasparitis A, Hanauer SB, Hart J. Side-to-side isoperistaltic strictureplasty in extensive Crohn's disease: a prospective longitudinal study. Ann Surg 2000;232:401-8.CrossRefPubMedCentralPubMed
4.
go back to reference Bellolio F, Cohen Z, MacRae HM, O'Connor BI, Victor JC, Huang H, McLeod RS. Strictureplasty in selected Crohn's disease patients results in acceptable long-term outcome. DisColon and Rectum 2012;55:864-9.CrossRef Bellolio F, Cohen Z, MacRae HM, O'Connor BI, Victor JC, Huang H, McLeod RS. Strictureplasty in selected Crohn's disease patients results in acceptable long-term outcome. DisColon and Rectum 2012;55:864-9.CrossRef
5.
go back to reference Yamamoto T. Factors affecting recurrence after surgery for Crohn's disease. WJG 2005;1:3971-9. Yamamoto T. Factors affecting recurrence after surgery for Crohn's disease. WJG 2005;1:3971-9.
6.
go back to reference Fazio VW, Marchetti F, Church M, Goldblum JR, Lavery C, Hull TL, Milsom JW, Strong SA, Oakley JR, Secic M. Effect of resection margins on the recurrence of Crohn's disease in the small bowel. A randomized controlled trial. Ann Surg 1996;224:563-71; discussion 71-3.CrossRefPubMedCentralPubMed Fazio VW, Marchetti F, Church M, Goldblum JR, Lavery C, Hull TL, Milsom JW, Strong SA, Oakley JR, Secic M. Effect of resection margins on the recurrence of Crohn's disease in the small bowel. A randomized controlled trial. Ann Surg 1996;224:563-71; discussion 71-3.CrossRefPubMedCentralPubMed
7.
go back to reference Ozuner G, Fazio VW, Lavery IC, Milsom JW, Strong SA. Reoperative rates for Crohn's disease following strictureplasty. Long-term analysis. DisColon Rectum 1996;39:1199-203.CrossRef Ozuner G, Fazio VW, Lavery IC, Milsom JW, Strong SA. Reoperative rates for Crohn's disease following strictureplasty. Long-term analysis. DisColon Rectum 1996;39:1199-203.CrossRef
8.
go back to reference Fichera A, Lovadina S, Rubin M, Cimino F, Hurst RD, Michelassi F. Patterns and operative treatment of recurrent Crohn's disease: a prospective longitudinal study. Surgery 2006;140:649-54.CrossRefPubMed Fichera A, Lovadina S, Rubin M, Cimino F, Hurst RD, Michelassi F. Patterns and operative treatment of recurrent Crohn's disease: a prospective longitudinal study. Surgery 2006;140:649-54.CrossRefPubMed
11.
go back to reference Delaney CP, Fazio VW. Crohn’s disease of the small bowel. Surg ClinNorth America 2001;81:137-58, ix.CrossRef Delaney CP, Fazio VW. Crohn’s disease of the small bowel. Surg ClinNorth America 2001;81:137-58, ix.CrossRef
12.
go back to reference Yamamoto T. Strictureplasty or resection for small-bowel Crohn’s disease? Dis Colon Rectum 2012;55:e382-3.CrossRefPubMed Yamamoto T. Strictureplasty or resection for small-bowel Crohn’s disease? Dis Colon Rectum 2012;55:e382-3.CrossRefPubMed
13.
go back to reference Cristaldi M, Sampietro GM, Danelli PG, Bollani S, Bianchi Porro G, Taschieri AM. Long-term results and multivariate analysis of prognostic factors in 138 consecutive patients operated on for Crohn's disease using "bowel-sparing" techniques. AmJSurg 2000;179:266-70. Cristaldi M, Sampietro GM, Danelli PG, Bollani S, Bianchi Porro G, Taschieri AM. Long-term results and multivariate analysis of prognostic factors in 138 consecutive patients operated on for Crohn's disease using "bowel-sparing" techniques. AmJSurg 2000;179:266-70.
14.
go back to reference Greenstein AJ, Zhang LP, Miller AT, Yung E, Branco BC, Sachar DB, et al. Relationship of the number of Crohn's strictures and strictureplasties to postoperative recurrence. J American Coll Surg 2009;208:1065-70.CrossRef Greenstein AJ, Zhang LP, Miller AT, Yung E, Branco BC, Sachar DB, et al. Relationship of the number of Crohn's strictures and strictureplasties to postoperative recurrence. J American Coll Surg 2009;208:1065-70.CrossRef
15.
go back to reference Yamamoto T, Keighley MR. Factors affecting the incidence of postoperative septic complications and recurrence after strictureplasty for jejunoileal Crohn's disease. AmJ Surg 1999;178:240-5.CrossRef Yamamoto T, Keighley MR. Factors affecting the incidence of postoperative septic complications and recurrence after strictureplasty for jejunoileal Crohn's disease. AmJ Surg 1999;178:240-5.CrossRef
16.
go back to reference Riss S, Schuster I, Papay P, Mittlbock M, Stift A. Repeat intestinal resections increase the risk of recurrence of Crohn's disease. DisColon Rectum 2013;56:881-7.CrossRef Riss S, Schuster I, Papay P, Mittlbock M, Stift A. Repeat intestinal resections increase the risk of recurrence of Crohn's disease. DisColon Rectum 2013;56:881-7.CrossRef
17.
go back to reference Dietz DW, Laureti S, Strong SA, Hull TL, Church J, Remzi FH, et al. Safety and longterm efficacy of strictureplasty in 314 patients with obstructing small bowel Crohn's disease. J Am CollSurg 2001;192:330-7; discussion 7-8. Dietz DW, Laureti S, Strong SA, Hull TL, Church J, Remzi FH, et al. Safety and longterm efficacy of strictureplasty in 314 patients with obstructing small bowel Crohn's disease. J Am CollSurg 2001;192:330-7; discussion 7-8.
18.
go back to reference Michelassi F, Taschieri A, Tonelli F, Sasaki I, Poggioli G, Fazio V, et al. An international, multicenter, prospective, observational study of the side-to-side isoperistaltic strictureplasty in Crohn's disease. Dis Colon Rectum 2007;50:277-84.CrossRefPubMed Michelassi F, Taschieri A, Tonelli F, Sasaki I, Poggioli G, Fazio V, et al. An international, multicenter, prospective, observational study of the side-to-side isoperistaltic strictureplasty in Crohn's disease. Dis Colon Rectum 2007;50:277-84.CrossRefPubMed
19.
go back to reference Binion DG, Theriot KR, Shidham S, Lundeen S, Hatoum O, Lim HJ, et al. Clinical factors contributing to rapid reoperation for Crohn's disease patients undergoing resection and/or strictureplasty. J Gastro Surg 2007;11:1692-8; dicussion 8.CrossRef Binion DG, Theriot KR, Shidham S, Lundeen S, Hatoum O, Lim HJ, et al. Clinical factors contributing to rapid reoperation for Crohn's disease patients undergoing resection and/or strictureplasty. J Gastro Surg 2007;11:1692-8; dicussion 8.CrossRef
20.
go back to reference Campbell L, Ambe R, Weaver J, Marcus SM, Cagir B. Comparison of conventional and nonconventional strictureplasties in Crohn's disease: a systematic review and meta-analysis. Dis Colon Rectum. 2012;55:714-26.CrossRefPubMed Campbell L, Ambe R, Weaver J, Marcus SM, Cagir B. Comparison of conventional and nonconventional strictureplasties in Crohn's disease: a systematic review and meta-analysis. Dis Colon Rectum. 2012;55:714-26.CrossRefPubMed
21.
go back to reference Tichansky D, Cagir B, Yoo E, Marcus SM, Fry RD. Strictureplasty for Crohn's disease: meta-analysis. DisColonRectum 2000;43:911-9. Tichansky D, Cagir B, Yoo E, Marcus SM, Fry RD. Strictureplasty for Crohn's disease: meta-analysis. DisColonRectum 2000;43:911-9.
22.
go back to reference Yamamoto T, Allan RN, Keighley MR. Risk factors for intra-abdominal sepsis after surgery in Crohn's disease. DisColon Rectum 2000;43:1141-5.CrossRef Yamamoto T, Allan RN, Keighley MR. Risk factors for intra-abdominal sepsis after surgery in Crohn's disease. DisColon Rectum 2000;43:1141-5.CrossRef
23.
go back to reference Tay GS, Binion DG, Eastwood D, Otterson MF. Multivariate analysis suggests improved perioperative outcome in Crohn's disease patients receiving immunomodulator therapy after segmental resection and/or strictureplasty. Surgery 2003;134:565-72; discussion 72-3.CrossRefPubMed Tay GS, Binion DG, Eastwood D, Otterson MF. Multivariate analysis suggests improved perioperative outcome in Crohn's disease patients receiving immunomodulator therapy after segmental resection and/or strictureplasty. Surgery 2003;134:565-72; discussion 72-3.CrossRefPubMed
24.
go back to reference Jess T, Riis L, Vind I, Winther KV, Borg S, Binder V, et al. Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: a population-based study from Copenhagen, Denmark. Inflamm Bowel Dis 2007;13:481-9.CrossRefPubMed Jess T, Riis L, Vind I, Winther KV, Borg S, Binder V, et al. Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: a population-based study from Copenhagen, Denmark. Inflamm Bowel Dis 2007;13:481-9.CrossRefPubMed
25.
go back to reference Loftus EV, Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology 2004;126:1504-17.CrossRefPubMed Loftus EV, Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology 2004;126:1504-17.CrossRefPubMed
26.
go back to reference Wolters FL, Russel MG, Stockbrugger RW. Systematic review: has disease outcome in Crohn's disease changed during the last four decades? Aliment Pharmacol&Therapeut 2004;20:483-96.CrossRef Wolters FL, Russel MG, Stockbrugger RW. Systematic review: has disease outcome in Crohn's disease changed during the last four decades? Aliment Pharmacol&Therapeut 2004;20:483-96.CrossRef
27.
go back to reference Hanauer SB, Feagan BG, Lichtenstein GR, Mayer LF, Schreiber S, Colombel JF, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002 4;359:1541-9. Hanauer SB, Feagan BG, Lichtenstein GR, Mayer LF, Schreiber S, Colombel JF, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002 4;359:1541-9.
28.
go back to reference Kornbluth A. Infliximab approved for use in Crohn's disease: a report on the FDA GI Advisory Committee conference. Inflamm Bowel Dis 1998;4:328-9.PubMed Kornbluth A. Infliximab approved for use in Crohn's disease: a report on the FDA GI Advisory Committee conference. Inflamm Bowel Dis 1998;4:328-9.PubMed
29.
go back to reference El-Hussuna A, Krag A, Olaison G, Bendtsen F, Gluud LL. The effect of anti-tumor necrosis factor alpha agents on postoperative anastomotic complications in Crohn's disease: a systematic review. DisColon Rectum 2013;56:1423-33.CrossRef El-Hussuna A, Krag A, Olaison G, Bendtsen F, Gluud LL. The effect of anti-tumor necrosis factor alpha agents on postoperative anastomotic complications in Crohn's disease: a systematic review. DisColon Rectum 2013;56:1423-33.CrossRef
30.
go back to reference Samimi R, Flasar MH, Kavic S, Tracy K, Cross RK. Outcome of medical treatment of stricturing and penetrating Crohn's disease: a retrospective study. Inflamm Bowel Dis 2010;16:1187-94.CrossRefPubMed Samimi R, Flasar MH, Kavic S, Tracy K, Cross RK. Outcome of medical treatment of stricturing and penetrating Crohn's disease: a retrospective study. Inflamm Bowel Dis 2010;16:1187-94.CrossRefPubMed
31.
go back to reference Wibmer AG, Kroesen AJ, Grone J, Buhr HJ, Ritz JP. Comparison of strictureplasty and endoscopic balloon dilatation for stricturing Crohn's disease—review of the literature. Intl JColorectal Dis 2010;25:1149-57.CrossRef Wibmer AG, Kroesen AJ, Grone J, Buhr HJ, Ritz JP. Comparison of strictureplasty and endoscopic balloon dilatation for stricturing Crohn's disease—review of the literature. Intl JColorectal Dis 2010;25:1149-57.CrossRef
Metadata
Title
Strictureplasty for Treatment of Crohn’s Disease: an ACS-NSQIP Database Analysis
Authors
Cristina B. Geltzeiler
J. Isaac Young
Brian S. Diggs
Kian Keyashian
Karen Deveney
Kim C. Lu
V. Liana Tsikitis
Daniel O. Herzig
Publication date
01-05-2015
Publisher
Springer US
Published in
Journal of Gastrointestinal Surgery / Issue 5/2015
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-015-2749-8

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