Skip to main content
Top
Published in: International Urogynecology Journal 1/2021

01-01-2021 | Stress Incontinence | Original Article

Stress urinary incontinence after transvaginal mesh surgery for anterior and apical prolapse: preoperative risk factors

Authors: Mathilde Bideau, Lucie Allègre, Geertje Callewaert, Brigitte Fatton, Renaud de Tayrac

Published in: International Urogynecology Journal | Issue 1/2021

Login to get access

Abstract

Introduction and hypothesis

Debate persists over whether surgery to correct pelvic organ prolapse (POP) should be combined with midurethral sling (MUS) insertion. The aim of this study was to evaluate the incidence of stress urinary incontinence (SUI) up to 12 months after transvaginal mesh surgery, with or without MUS, and to identify risk factors for postoperative SUI.

Methods

This retrospective single-center study included patients who underwent transvaginal mesh surgery with Uphold™ between October 2010 and December 2017. The primary outcome was the prevalence of SUI at 12 months postoperatively. Univariate and multivariate logistic regression was used to identify risks factors for postoperative SUI.

Results

Of the 308 women included, 123 (40%) were continent (no SUI), 108 (35%) had SUI, and 76 (25%) had occult SUI. Forty-nine patients (15.9%) had a concomitant MUS procedure. At 12 months after surgery, 35.9% of patients without concomitant MUS had SUI vs 14.3% with (p = 0.003). Thirty-five patients (29%) developed de novo SUI. Postoperative complications were more common in patients with concomitant MUS (30.6% vs 17%; p = 0.003). The best predictor of postoperative SUI was the presence of preoperative SUI (OR 2.52 (1.25–5.09). Concomitant MUS (p < 0.001), and prior POP surgery (p = 0.034) were protective factors for postoperative SUI.

Conclusion

Preoperative SUI is the most important risk factor for postoperative SUI. However, given the higher risk of postoperative complications with concomitant MUS and the acceptable rate of de novo SUI rate without it, two-stage surgery seems preferable for patients with preoperative SUI.
Literature
1.
go back to reference Slieker-ten Hove MCP, Pool-Goudzwaard AL, Eijkemans MJC, Steegers-Theunissen RPM, Burger CW, Vierhout ME. The prevalence of pelvic organ prolapse symptoms and signs and their relation with bladder and bowel disorders in a general female population. Int Urogynecol J Pelvic Floor Dysfunct. 2009;20:1037–45.CrossRef Slieker-ten Hove MCP, Pool-Goudzwaard AL, Eijkemans MJC, Steegers-Theunissen RPM, Burger CW, Vierhout ME. The prevalence of pelvic organ prolapse symptoms and signs and their relation with bladder and bowel disorders in a general female population. Int Urogynecol J Pelvic Floor Dysfunct. 2009;20:1037–45.CrossRef
2.
go back to reference Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol. 1997;89:501–6.CrossRef Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol. 1997;89:501–6.CrossRef
3.
go back to reference Maher C, Feiner B, Baessler K, Christmann-Schmid C, Haya N, Marjoribanks J. Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse. Cochrane Database Syst Rev. 2016;2:CD012079.PubMed Maher C, Feiner B, Baessler K, Christmann-Schmid C, Haya N, Marjoribanks J. Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse. Cochrane Database Syst Rev. 2016;2:CD012079.PubMed
4.
go back to reference Baessler K, Christmann-Schmid C, Maher C, Haya N, Crawford TJ, Brown J. Surgery for women with pelvic organ prolapse with or without stress urinary incontinence. Cochrane Database Syst Rev. 2018;8:CD013108.PubMed Baessler K, Christmann-Schmid C, Maher C, Haya N, Crawford TJ, Brown J. Surgery for women with pelvic organ prolapse with or without stress urinary incontinence. Cochrane Database Syst Rev. 2018;8:CD013108.PubMed
5.
go back to reference Van der Ploeg JM, Oude Rengerink K, van der Steen A, van Leeuwen JHS, van der Vaart CH, Roovers J-PWR, et al. Vaginal prolapse repair with or without a midurethral sling in women with genital prolapse and occult stress urinary incontinence: a randomized trial. Int Urogynecol J. 2016;27:1029–38.CrossRef Van der Ploeg JM, Oude Rengerink K, van der Steen A, van Leeuwen JHS, van der Vaart CH, Roovers J-PWR, et al. Vaginal prolapse repair with or without a midurethral sling in women with genital prolapse and occult stress urinary incontinence: a randomized trial. Int Urogynecol J. 2016;27:1029–38.CrossRef
6.
go back to reference Lo T-S, Pue LB, Tan YL, Hsieh W-C, Kao CC, Uy-Patrimonio MC. Anterior-apical single-incision mesh surgery (uphold): 1-year outcomes on lower urinary tract symptoms, anatomy and ultrasonography. Int Urogynecol J. 2019;30:1163–72.CrossRef Lo T-S, Pue LB, Tan YL, Hsieh W-C, Kao CC, Uy-Patrimonio MC. Anterior-apical single-incision mesh surgery (uphold): 1-year outcomes on lower urinary tract symptoms, anatomy and ultrasonography. Int Urogynecol J. 2019;30:1163–72.CrossRef
7.
go back to reference Altman D, Mikkola TS, Bek KM, Rahkola-Soisalo P, Gunnarsson J, Engh ME, et al. Pelvic organ prolapse repair using the uphold™ vaginal support system: a 1-year multicenter study. Int Urogynecol J. 2016;27:1337–45.CrossRef Altman D, Mikkola TS, Bek KM, Rahkola-Soisalo P, Gunnarsson J, Engh ME, et al. Pelvic organ prolapse repair using the uphold™ vaginal support system: a 1-year multicenter study. Int Urogynecol J. 2016;27:1337–45.CrossRef
8.
go back to reference Allègre L, Debodinance P, Demattei C, Fabbro Peray P, Cayrac M, Fritel X, et al. Clinical evaluation of the uphold LITE mesh for the surgical treatment of anterior and apical prolapse: a prospective, multicentre trial. Neurourol Urodyn. 2019;38:2242–9.CrossRef Allègre L, Debodinance P, Demattei C, Fabbro Peray P, Cayrac M, Fritel X, et al. Clinical evaluation of the uphold LITE mesh for the surgical treatment of anterior and apical prolapse: a prospective, multicentre trial. Neurourol Urodyn. 2019;38:2242–9.CrossRef
9.
go back to reference Wei JT, Nygaard I, Richter HE, Nager CW, Barber MD, Kenton K, et al. A midurethral sling to reduce incontinence after vaginal prolapse repair. N Engl J Med. 2012;366:2358–67.CrossRef Wei JT, Nygaard I, Richter HE, Nager CW, Barber MD, Kenton K, et al. A midurethral sling to reduce incontinence after vaginal prolapse repair. N Engl J Med. 2012;366:2358–67.CrossRef
10.
go back to reference Baessler K, Maher C. Pelvic organ prolapse surgery and bladder function. Int Urogynecol J. 2013;24:1843–52.CrossRef Baessler K, Maher C. Pelvic organ prolapse surgery and bladder function. Int Urogynecol J. 2013;24:1843–52.CrossRef
11.
go back to reference Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, et al. An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction. Neurourol Urodyn. 2010;29:4–20.CrossRef Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, et al. An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction. Neurourol Urodyn. 2010;29:4–20.CrossRef
12.
go back to reference De Tayrac R, Faillie J-L, Gaillet S, Boileau L, Triopon G, Letouzey V. Analysis of the learning curve of bilateral anterior sacrospinous ligament suspension associated with anterior mesh repair. Eur J Obstet Gynecol Reprod Biol. 2012;165:361–5.CrossRef De Tayrac R, Faillie J-L, Gaillet S, Boileau L, Triopon G, Letouzey V. Analysis of the learning curve of bilateral anterior sacrospinous ligament suspension associated with anterior mesh repair. Eur J Obstet Gynecol Reprod Biol. 2012;165:361–5.CrossRef
13.
go back to reference Borstad E, Abdelnoor M, Staff AC, Kulseng-Hanssen S. Surgical strategies for women with pelvic organ prolapse and urinary stress incontinence. Int Urogynecol J. 2010;21:179–86.CrossRef Borstad E, Abdelnoor M, Staff AC, Kulseng-Hanssen S. Surgical strategies for women with pelvic organ prolapse and urinary stress incontinence. Int Urogynecol J. 2010;21:179–86.CrossRef
14.
go back to reference Lensen EJM, Withagen MIJ, Kluivers KB, Milani AL, Vierhout ME. Urinary incontinence after surgery for pelvic organ prolapse. Neurourol Urodyn. 2013;32:455–9.CrossRef Lensen EJM, Withagen MIJ, Kluivers KB, Milani AL, Vierhout ME. Urinary incontinence after surgery for pelvic organ prolapse. Neurourol Urodyn. 2013;32:455–9.CrossRef
15.
go back to reference Alas AN, Chinthakanan O, Espaillat L, Plowright L, Davila GW, Aguilar VC. De novo stress urinary incontinence after pelvic organ prolapse surgery in women without occult incontinence. Int Urogynecol J. 2017;28:583–90.CrossRef Alas AN, Chinthakanan O, Espaillat L, Plowright L, Davila GW, Aguilar VC. De novo stress urinary incontinence after pelvic organ prolapse surgery in women without occult incontinence. Int Urogynecol J. 2017;28:583–90.CrossRef
16.
go back to reference Kasturi S, Diaz SI, McDermott CD, Woodman PJ, Bump RC, Terry CL, et al. De novo stress urinary incontinence after negative prolapse reduction stress testing for total vaginal mesh procedures: incidence and risk factors. Am J Obstet Gynecol. 2011;205:487.e1–4.CrossRef Kasturi S, Diaz SI, McDermott CD, Woodman PJ, Bump RC, Terry CL, et al. De novo stress urinary incontinence after negative prolapse reduction stress testing for total vaginal mesh procedures: incidence and risk factors. Am J Obstet Gynecol. 2011;205:487.e1–4.CrossRef
17.
go back to reference Jundt K, Wagner S, von Bodungen V, Friese K, Peschers UM. Occult incontinence in women with pelvic organ prolapse—does it matter? Eur J Med Res. 2010;15:112–6.CrossRef Jundt K, Wagner S, von Bodungen V, Friese K, Peschers UM. Occult incontinence in women with pelvic organ prolapse—does it matter? Eur J Med Res. 2010;15:112–6.CrossRef
18.
go back to reference Brubaker L, Nygaard I, Richter HE, Visco A, Weber AM, Cundiff GW, et al. Two-year outcomes after sacrocolpopexy with and without Burch to prevent stress urinary incontinence. Obstet Gynecol. 2008;112:49–55.CrossRef Brubaker L, Nygaard I, Richter HE, Visco A, Weber AM, Cundiff GW, et al. Two-year outcomes after sacrocolpopexy with and without Burch to prevent stress urinary incontinence. Obstet Gynecol. 2008;112:49–55.CrossRef
19.
go back to reference Oride A, Kanasaki H, Hara T, Kyo S. Postoperative outcomes following tension-free vaginal mesh surgery for pelvic organ prolapse: a retrospective study. Urol J. 2019;16:581–5.PubMed Oride A, Kanasaki H, Hara T, Kyo S. Postoperative outcomes following tension-free vaginal mesh surgery for pelvic organ prolapse: a retrospective study. Urol J. 2019;16:581–5.PubMed
20.
go back to reference Lapitan MCM, Cody JD, Mashayekhi A. Open retropubic colposuspension for urinary incontinence in women. Cochrane Database Syst Rev. 2017;7:CD002912.PubMed Lapitan MCM, Cody JD, Mashayekhi A. Open retropubic colposuspension for urinary incontinence in women. Cochrane Database Syst Rev. 2017;7:CD002912.PubMed
21.
go back to reference Dean N, Ellis G, Herbison GP, Wilson D, Mashayekhi A. Laparoscopic colposuspension for urinary incontinence in women. Cochrane Database Syst Rev. 2017;7:CD002239.PubMed Dean N, Ellis G, Herbison GP, Wilson D, Mashayekhi A. Laparoscopic colposuspension for urinary incontinence in women. Cochrane Database Syst Rev. 2017;7:CD002239.PubMed
22.
go back to reference Brown JS, Sawaya G, Thom DH, Grady D. Hysterectomy and urinary incontinence: a systematic review. Lancet. 2000;356:535–9.CrossRef Brown JS, Sawaya G, Thom DH, Grady D. Hysterectomy and urinary incontinence: a systematic review. Lancet. 2000;356:535–9.CrossRef
23.
go back to reference Longo PS, Borbily LV, Glina FPA. Urinary incontinence following subtotal and total hysterectomy: a systematic review. Einstein (Sao Paulo). 2019;17:eRW4320.CrossRef Longo PS, Borbily LV, Glina FPA. Urinary incontinence following subtotal and total hysterectomy: a systematic review. Einstein (Sao Paulo). 2019;17:eRW4320.CrossRef
24.
go back to reference Lo T-S, Bt Karim N, Nawawi EA, Wu P-Y, Nusee Z. Predictors for de novo stress urinary incontinence following extensive pelvic reconstructive surgery. Int Urogynecol J. 2015;26:1313–9.CrossRef Lo T-S, Bt Karim N, Nawawi EA, Wu P-Y, Nusee Z. Predictors for de novo stress urinary incontinence following extensive pelvic reconstructive surgery. Int Urogynecol J. 2015;26:1313–9.CrossRef
25.
go back to reference Tran H, Chung DE. Incidence and management of de novo lower urinary tract symptoms after pelvic organ prolapse repair. Curr Urol Rep. 2017;18:87.CrossRef Tran H, Chung DE. Incidence and management of de novo lower urinary tract symptoms after pelvic organ prolapse repair. Curr Urol Rep. 2017;18:87.CrossRef
Metadata
Title
Stress urinary incontinence after transvaginal mesh surgery for anterior and apical prolapse: preoperative risk factors
Authors
Mathilde Bideau
Lucie Allègre
Geertje Callewaert
Brigitte Fatton
Renaud de Tayrac
Publication date
01-01-2021
Publisher
Springer International Publishing
Published in
International Urogynecology Journal / Issue 1/2021
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-020-04363-9

Other articles of this Issue 1/2021

International Urogynecology Journal 1/2021 Go to the issue