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01-06-2011 | Bone Quality Seminars: Bone Fracture Healing and Strengthening

Strategies for improving the efficacy of bioengineered bone constructs: a perspective

Authors: H. Petite, K. Vandamme, L. Monfoulet, D. Logeart-Avramoglou

Published in: Osteoporosis International | Issue 6/2011

Abstract

Bioengineered bone scaffolds are intended for use in large bone defects. Successful bone constructs should stimulate and support both the onset and the continuance of bone ingrowth. In an attempt to improve their performance and to compete with the one of autologous bone grafts, a growing symbiosis at the biological and material level is required. Recent advances have been made to further exploit the osteogenic potential of MSCs in scaffold development. Current research encompasses new strategies for reducing cell death after implantation and the manufacturing of tailored, instructive scaffolds.

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Title: Strategies for improving the efficacy of bioengineered bone constructs: a perspective
Authors: H. Petite
K. Vandamme
L. Monfoulet
D. Logeart-Avramoglou
Publication date: 01-06-2011
Publisher: Springer-Verlag
Published in: Osteoporosis International / Issue 6/2011
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-011-1614-1

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Strategies for improving the efficacy of bioengineered bone constructs: a perspective

Abstract

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