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Published in: International Journal of Clinical Pharmacy 4/2012

01-08-2012 | Research Article

Storage and disposal of unused medications: knowledge, behavior, and attitudes among Serbian people

Authors: Milica P. Kusturica, Ana Sabo, Zdenko Tomic, Olga Horvat, Zdravko Šolak

Published in: International Journal of Clinical Pharmacy | Issue 4/2012

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Abstract

Background Improper disposal of medications potentially poses a significant environmental risk and storage of expired and unused medications in households provides an increased risk of accidental childhood poisonings. Objective The objective of this study was to investigate the storage and disposal habits of medications amongst the population in the South Bačka District of Serbia, and to gain insight into the attitudes and knowledge of the population about the proper disposal of medications. Setting Households in South Bačka District. Method The study was conducted during the 6-month period from February 2010 to July 2010 and involved a random sample of households. The questionnaire-based study was performed by a trained interviewer. Main outcome measure number of expired and unused medications in families, behavior and knowledge about the disposal of medications. Results Of 230 families, 208 (108 urban and 100 rural) agreed to participate and complete the questionnaire(90 % response rate). The drugs were mostly kept in a specific place-home pharmacy (89.8 % [urban] and 89.0 % [rural]). Exposure of children to medications in the home environment was similar in urban and rural families (19.6 % [urban] and 23.1 % [rural]). The frequency of expired medications was not observed to be different between the urban and rural households (10.3 % [urban] and 11.8 % [rural]). The most common method for disposal of household medications is disposal in the garbage (85.6 % [urban] and 74.5 % [rural]) or in the toilet (8.7 % [urban] and 6.4 % [rural]). However, inconsistent with disposal practices, half of the urban and rural participants thought that throwing medications in the garbage, toilet, or sink has a detrimental effect on the environment. Conclusion Public services in Serbia, including government and health sectors, need to be more proactive about educating people on how to store and dispose medications, as well as finding a way for implementation of the law on medications wastage destruction.
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Literature
1.
go back to reference Bound JP, Voulvoulis N. Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United Kingdom. Environ Health Perspect. 2005;113(12):1705–11.PubMedCrossRef Bound JP, Voulvoulis N. Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United Kingdom. Environ Health Perspect. 2005;113(12):1705–11.PubMedCrossRef
2.
go back to reference Abahussain EA, Ball DE. Disposal of unwanted medicines from households in Kuwait. Pharm World Sci. 2007;29(4):368–73.PubMedCrossRef Abahussain EA, Ball DE. Disposal of unwanted medicines from households in Kuwait. Pharm World Sci. 2007;29(4):368–73.PubMedCrossRef
3.
go back to reference Kyingi KS, Lauvo JAK. Drugs in the home: danger and waste. World Health Forum. 1993;14:381–4. Kyingi KS, Lauvo JAK. Drugs in the home: danger and waste. World Health Forum. 1993;14:381–4.
4.
go back to reference Beirens TM, van Beeck EF, Dekker R, Brug J, Raat H. Unsafe storage of poisons in homes with toddlers. Accid Anal Prev. 2006;38:772–6.PubMedCrossRef Beirens TM, van Beeck EF, Dekker R, Brug J, Raat H. Unsafe storage of poisons in homes with toddlers. Accid Anal Prev. 2006;38:772–6.PubMedCrossRef
5.
go back to reference Franklin RL, Rodgers GB. Unintentional child poisoning treaated in United States hospital emergency departments: national estimates of incident cases, population-based poisoninig rates, and product involvement. Pediatrics. 2008;122:1244–51.PubMedCrossRef Franklin RL, Rodgers GB. Unintentional child poisoning treaated in United States hospital emergency departments: national estimates of incident cases, population-based poisoninig rates, and product involvement. Pediatrics. 2008;122:1244–51.PubMedCrossRef
6.
go back to reference Tong AY, Peake BM, Braund R. Disposal practices for unused medications around the world. Environ Int. 2011;37(1):292–8.PubMedCrossRef Tong AY, Peake BM, Braund R. Disposal practices for unused medications around the world. Environ Int. 2011;37(1):292–8.PubMedCrossRef
7.
go back to reference Zargarzadeh AH, Tavakoli N, Hassanzadeh A. A survey on the extent of medication storage and wastage in urban Iranian households. Clin Ther. 2005;27:970–8.PubMedCrossRef Zargarzadeh AH, Tavakoli N, Hassanzadeh A. A survey on the extent of medication storage and wastage in urban Iranian households. Clin Ther. 2005;27:970–8.PubMedCrossRef
8.
go back to reference Serbian Rule on Medical Waste Management (2010). State Gazzete No 78/Nov 2010. Serbian Rule on Medical Waste Management (2010). State Gazzete No 78/Nov 2010.
11.
go back to reference Persson M, Sabelström E, Gunnarsson B. Handling of unused prescription drugs-knowledge, behavior and attitude among Swedish people. Environ Int. 2009;35(5):771–4.PubMedCrossRef Persson M, Sabelström E, Gunnarsson B. Handling of unused prescription drugs-knowledge, behavior and attitude among Swedish people. Environ Int. 2009;35(5):771–4.PubMedCrossRef
12.
go back to reference Lwanga SK, Lemeshow S. Sample size determination in health studies. Geneva: World Health Organization; 1991. Lwanga SK, Lemeshow S. Sample size determination in health studies. Geneva: World Health Organization; 1991.
13.
go back to reference Aljinovic-Vučić V, Trkulja V, Lackovic Z. Content of home pharmacy and self-medication practices in households of pharmacy and medical students in Zagreb, Croatia: findings in 2001 with a reference to 1977. Croat Med J. 2005;46(1):74–80.PubMed Aljinovic-Vučić V, Trkulja V, Lackovic Z. Content of home pharmacy and self-medication practices in households of pharmacy and medical students in Zagreb, Croatia: findings in 2001 with a reference to 1977. Croat Med J. 2005;46(1):74–80.PubMed
14.
go back to reference Stilinović N, Vukmirović S, Milijašević B, Horvat O, Sahman M, Tomić Z, Šramka M, Sabova A. Lieky v domacich lekarničkach v Srbsku a na Slovensku: ich nebezpečie na zdravie uživatelov [Drugs in home in Serbia and Slovakia: danger to health] Zdravotnictvo a socialna praca 2008; 3(3–4): 15–21. Stilinović N, Vukmirović S, Milijašević B, Horvat O, Sahman M, Tomić Z, Šramka M, Sabova A. Lieky v domacich lekarničkach v Srbsku a na Slovensku: ich nebezpečie na zdravie uživatelov [Drugs in home in Serbia and Slovakia: danger to health] Zdravotnictvo a socialna praca 2008; 3(3–4): 15–21.
15.
go back to reference De Bolle L, Verrue C, Mehuys E, Adriaens E, Remon JP, Van Bortel L, Christiaens T. Home medication cabinets and self-medication: a source of potential health threats? J Pharm Belg. 2009;1:1–4.PubMed De Bolle L, Verrue C, Mehuys E, Adriaens E, Remon JP, Van Bortel L, Christiaens T. Home medication cabinets and self-medication: a source of potential health threats? J Pharm Belg. 2009;1:1–4.PubMed
16.
go back to reference Horvat O, Mijatović V, Paut M, Tomić Z, Mijatović V. Antibiotici kupljeni bez recepta na teritoriji Južnobačkog okruga [Antibiotics purchased without prescription in South Bačka District]. 3. Nedelja bolničke i kliničke farmakologije, Beograd, Srbija; 2011. p. 42–43. Horvat O, Mijatović V, Paut M, Tomić Z, Mijatović V. Antibiotici kupljeni bez recepta na teritoriji Južnobačkog okruga [Antibiotics purchased without prescription in South Bačka District]. 3. Nedelja bolničke i kliničke farmakologije, Beograd, Srbija; 2011. p. 42–43.
17.
go back to reference Tourinho FS, Bucaretchi F, Stephan C, Cordeiro R. Home medicine chests and their relationship with self-medication in children and adolescents. J Pediatr. 2008;84(5):416–22.CrossRef Tourinho FS, Bucaretchi F, Stephan C, Cordeiro R. Home medicine chests and their relationship with self-medication in children and adolescents. J Pediatr. 2008;84(5):416–22.CrossRef
18.
go back to reference Abou-Auda HS. An economic assessement of the extent of medication use and wastage among families in Saudi Arabia and Arabian Gulf countries. Clin Ther. 2003;25(4):1276–92.PubMedCrossRef Abou-Auda HS. An economic assessement of the extent of medication use and wastage among families in Saudi Arabia and Arabian Gulf countries. Clin Ther. 2003;25(4):1276–92.PubMedCrossRef
19.
go back to reference Ćalasan J, Mijatović V, Horvat O, Varga J, Sabo A, Stilinović N. The outpatient utilization of non-steroidal anti-inflammatory drugs in South Backa District. Serbia Int J Clin Pharm. 2011;33:246–51.CrossRef Ćalasan J, Mijatović V, Horvat O, Varga J, Sabo A, Stilinović N. The outpatient utilization of non-steroidal anti-inflammatory drugs in South Backa District. Serbia Int J Clin Pharm. 2011;33:246–51.CrossRef
20.
go back to reference Mijatović V, Ćalasan J, Horvat O, Sabo A, Tomić Z, Radulović V. Consumption of non-steroidal anti-inflammatory drugs in Serbia compared with Croatia and Denmark during 2005–2008 period. Eur J Clin Pharmacol. 2011;67(2):203–7.PubMedCrossRef Mijatović V, Ćalasan J, Horvat O, Sabo A, Tomić Z, Radulović V. Consumption of non-steroidal anti-inflammatory drugs in Serbia compared with Croatia and Denmark during 2005–2008 period. Eur J Clin Pharmacol. 2011;67(2):203–7.PubMedCrossRef
21.
go back to reference Boehringer SK. What’s the best way to dispose of medications? Pharmacist’s letter/Prescriber’s letter. Stockton: Environmental Protection Authority; 2004; 20: Number 200415. Boehringer SK. What’s the best way to dispose of medications? Pharmacist’s letter/Prescriber’s letter. Stockton: Environmental Protection Authority; 2004; 20: Number 200415.
22.
go back to reference Smith CA. Managing pharmaceutical waste—what pharmacists should know. J Pharm Soc. Wisconsin, Nov/Dec 2002;17–22. Smith CA. Managing pharmaceutical waste—what pharmacists should know. J Pharm Soc. Wisconsin, Nov/Dec 2002;17–22.
23.
go back to reference Krupiene J, Dvarioniene J. Pharmaceutical pathways to the environment in Lithuania. Environ Res Eng Manag. 2007;41:33–9. Krupiene J, Dvarioniene J. Pharmaceutical pathways to the environment in Lithuania. Environ Res Eng Manag. 2007;41:33–9.
24.
go back to reference Sharif SI, Abduelkarem AR, Bustami HA, Haddad LI, Khalil DS. Trends of home drug storage and use in different regions across the Northern Arab Emirates. Med Princ Pract. 2010;19(5):355–8.PubMedCrossRef Sharif SI, Abduelkarem AR, Bustami HA, Haddad LI, Khalil DS. Trends of home drug storage and use in different regions across the Northern Arab Emirates. Med Princ Pract. 2010;19(5):355–8.PubMedCrossRef
25.
go back to reference Daughton CG. Cradle to cradle stewardship of drugs for minimizing their environmental disposition while promoting human health. II Drug disposal, waste reduction, and future directions. Environ Health Perspect. 2003;111:775–85.PubMedCrossRef Daughton CG. Cradle to cradle stewardship of drugs for minimizing their environmental disposition while promoting human health. II Drug disposal, waste reduction, and future directions. Environ Health Perspect. 2003;111:775–85.PubMedCrossRef
26.
go back to reference Jones OA, Voulvoulis N, Lester JN. Potential impact of pharmaceuticals on environmental disposition while promoting human health. Bull World Health Organ. 2003;81:768–9.PubMed Jones OA, Voulvoulis N, Lester JN. Potential impact of pharmaceuticals on environmental disposition while promoting human health. Bull World Health Organ. 2003;81:768–9.PubMed
27.
go back to reference Daughton CG, Ternes TA. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ Health Perspect. 1999;107(Suppl 6):907–38.PubMedCrossRef Daughton CG, Ternes TA. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ Health Perspect. 1999;107(Suppl 6):907–38.PubMedCrossRef
28.
go back to reference Schwab BW, Hayes EP, Fiori JM, et al. Human pharmaceuticals in US surface waters: a human health risk assessment. Regul Toxicol Pharmacol. 2005;42:296–312.PubMedCrossRef Schwab BW, Hayes EP, Fiori JM, et al. Human pharmaceuticals in US surface waters: a human health risk assessment. Regul Toxicol Pharmacol. 2005;42:296–312.PubMedCrossRef
29.
go back to reference Webb S, Ternes T, Gibert M, Olejniczak K. Indirect human exposure to pharmaceuticals via drinking water. Toxicol Lett. 2003;142:157–67.PubMedCrossRef Webb S, Ternes T, Gibert M, Olejniczak K. Indirect human exposure to pharmaceuticals via drinking water. Toxicol Lett. 2003;142:157–67.PubMedCrossRef
30.
go back to reference Seehusen DA, Edwards J. Patient practices and beliefs concerning disposal of medications. J Am Board Fam Med. 2006;19(6):542–7.PubMedCrossRef Seehusen DA, Edwards J. Patient practices and beliefs concerning disposal of medications. J Am Board Fam Med. 2006;19(6):542–7.PubMedCrossRef
31.
go back to reference Braund R, Peake BM, Shieffelbien L. Disposal practices for unused medications in New Zealand. Environ Int. 2009;35:953–5.CrossRef Braund R, Peake BM, Shieffelbien L. Disposal practices for unused medications in New Zealand. Environ Int. 2009;35:953–5.CrossRef
32.
go back to reference Kotchen M, Kallaos J, Wheeler K, Wong C, Zahller M. Pharmaceuticals in wastewater: behaviour, preferences, and willingness to pay for a disposal program. J Environ Manag. 2009;90:1476–82.CrossRef Kotchen M, Kallaos J, Wheeler K, Wong C, Zahller M. Pharmaceuticals in wastewater: behaviour, preferences, and willingness to pay for a disposal program. J Environ Manag. 2009;90:1476–82.CrossRef
Metadata
Title
Storage and disposal of unused medications: knowledge, behavior, and attitudes among Serbian people
Authors
Milica P. Kusturica
Ana Sabo
Zdenko Tomic
Olga Horvat
Zdravko Šolak
Publication date
01-08-2012
Publisher
Springer Netherlands
Published in
International Journal of Clinical Pharmacy / Issue 4/2012
Print ISSN: 2210-7703
Electronic ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-012-9652-0

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