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01-11-2007 | Clinical-Patient Studies

Stevens-Johnson syndrome in children receiving phenobarbital therapy and cranial radiotherapy

Authors: Antonio Ruggiero, Paola Sabrina Buonuomo, Palma Maurizi, Maria Pia Cefalo, Mirta Corsello, Riccardo Riccardi

Published in: Journal of Neuro-Oncology | Issue 2/2007

Abstract

Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that most often appears as an adverse reaction to medication. In this report, we present two children with brain tumour who developed SJS while receiving cranial irradiation and anticonvulsant therapy with phenobarbital. Concomitant application of these two therapies may play an important role in the occurrence of the disease.

Forsyth PA, Weaver S, Fulton D, Brasher PMA, Sutherland G et al (2003) Prophylactic anticonvulsants in patients with brain tumour. Can J Neurol Sci 30(2):106–112PubMed

Sirven J, Wingerchuk DM, Drazkowski JF, Lyons MK, Zimmerman RS (2004) Seizure prophylaxis in patients with brain tumors: a meta-analysis. Mayo Clin Proc 79(12):1489–1494PubMedCrossRef

Glantz MJ, Cole BF, Forsyth PA, Recht LD, Wen PY et al (2000) Practice parameter: anticonvulsant prophylaxis in patients with newly diagnosed brain tumors. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 54(10):1886–1893PubMed

Kelly JP, Auquier A, Rzany B, Naldi L, Bastuji-Garin S et al (1995) An international collaborative case-control study of severe cutaneous adverse reactions (SCAR). Design and methods. J Clin Epidemiol 48(9):1099–1108PubMedCrossRef

Rzany B, Correia O, Kelly J, Naldi L, Auquier A, Stern R (1999) Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis during first weeks of antiepileptic therapy: a case-control study. Lancet 353(9171):2190–2194PubMedCrossRef

Oner Dincbas F, Yoruk S, Demirkesen C, Uzel O, Koca S (2004) Toxic epidermal necrolysis after cranial radiotherapy and phenytoin treatment. Onkologie 27(4):389–392PubMedCrossRef

Gomez-Criado MS, Ayani I, Leon-Colombo T, Ramos ML, Reneses MJ (2004) Stevens-Johnson syndrome, toxic epidermal necrolysis and phenytoin. Factors linked to a higher risk. Rev Neurol 38(11):1056–1060PubMed

Eralp Y, Aydiner A, Tas F, Saip P, Topuz E (2001) Stevens-Johnson syndrome in a patient receiving anticonvulsant therapy during cranial irradiation. Am J Clin Oncol 24(4):347–350PubMedCrossRef

Aguiar D, Pazo R, Duran I, Terrasa J, Arrivi A et al (2004) Toxic epidermal necrolysis in patients receiving anticonvulsants and cranial irradiation: a risk to consider. J Neurooncol 66(3):345–350PubMedCrossRef

10.

Dincbas FO, Yörük S, Demirkesen C, Uzel O, Koca S (2004) Toxic epidermal necrolysis after cranial radiotherapy and phenytoin treatment. Onkologie 27:389–392CrossRef

11.

Aydin F, Cokluk C, Senturk N, Aydin K, Canturk MT, Turanli AY (2006) Stevens-Johnson syndrome in two patients treated with cranial irradiation and phenytoin. J Eur Acad Dermatol Venereol 20:588PubMedCrossRef

12.

Khafaga YM, Jamshed A, Allam AA, Mourad WA, Ezzat A, Al Eisa A, Gray AJ, Schultz H (1999) Related articles, links Stevens-Johnson syndrome in patients on phenytoin and cranial radiotherapy. Acta Oncol 38(1):111–116PubMedCrossRef

13.

Bastuji-Garin S, Rzany B, Stern RS et al (1993) Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol 129:92–96PubMedCrossRef

14.

Ahmed I, Reichenberg J, Lucas A, Shehan JM (2004) Erythema multiforme associated with phenytoin and cranial radiation therapy: a report of three patients and review of the literature. Int J Dermatol 43(1):67–73PubMedCrossRef

15.

Wohrl S, Loewe R, Pickl WF, Stingl G, Wagner SN (2005) EMPACT syndrome. J Dtsch Dermatol Ges 3(1):39–43PubMedCrossRef

Title: Stevens-Johnson syndrome in children receiving phenobarbital therapy and cranial radiotherapy
Authors: Antonio Ruggiero
Paola Sabrina Buonuomo
Palma Maurizi
Maria Pia Cefalo
Mirta Corsello
Riccardo Riccardi
Publication date: 01-11-2007
Publisher: Springer US
Published in: Journal of Neuro-Oncology / Issue 2/2007
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-007-9399-y

2024 ASCO Annual Meeting

Springer Medicine

Stevens-Johnson syndrome in children receiving phenobarbital therapy and cranial radiotherapy

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

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