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Netherlands Heart Journal

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Open Access 01-08-2015 | Special Article

STEMI time delays: a clinical perspective

Editorial comment on the article by Verweij et al.

Authors: M-J. de Boer, F. Zijlstra

Published in: Netherlands Heart Journal | Issue 9/2015

Abstract

STEMI time delays have been introduced as a performance indicator or marker of quality of care. As they are only one part of a very complex medical process, one should be aware of concomitant issues that may be overlooked or even be more important with regard to clinical outcome of STEMI patients. In this overview we try to summarise the most important ones.

Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet. 2003;361:13–20.PubMedCrossRef

Zijlstra F, de Boer MJ, Hoorntje JCA, Reiffers S, Reiber JHC, Suryapranata H. A comparison of immediate coronary angioplasty with intravenous streptokinase in acute myocardial infarction. N Engl J Med. 1993;328:680–4.PubMedCrossRef

De Luca G, Suryapranata H, Ottervanger JP, Antman EM. Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay counts. Circulation. 2004;109:1223–5.PubMedCrossRef

Terkelsen CJ, Sorensen JT, Maeng M, et al. System delay and mortality among patients with STEMI treated with primary percutaneous coronary intervention. JAMA. 2010;304:763–771.PubMedCrossRef

Kontos MC, Wang Y, Chaudhry SI, Vetrovec GW, Curtis J, Messenger J, on behalf of NCDR. Lower hospital volume is associated with higher in-hospital mortality in patients undergoing primary percutaneous coronary intervention for ST-segment-elevation myocardial infarction. A report from the NCDR. Circ Cardiovasc Qual Outcomes. 2013;6:659–67.PubMedCrossRef

Curry LA, Spatz E, Cherlin E, et al. What distinguishes top-performing hospitals in acute myocardial infarction mortality rates? A qualitative study. Ann Intern Med. 2011;154:384–90.PubMedCrossRef

Postma S, Dambrink JH, de Boer MJ, et al. Prehospital triage in the ambulance reduces infarct size and improves clinical outcome. Am Heart J. 2011;161:276–82.PubMedCrossRef

Postma S, Dambrink JHE, de Boer MJ, et al. The influence of residential distance on time to treatment in ST-elevation myocardial infarction patients. Neth Heart J. 2014;11:513–9.CrossRef

Widimský P, Budesinský T, Vorác D, et al. ‘PRAGUE’ study group investigators. Long distance transport for primary angioplasty vs immediate thrombolysis in acute myocardial infarction: final results of the randomized national multicentre trial—PRAGUE-2. Eur Heart J. 2003;24:94–104.PubMedCrossRef

10.

Asseburg C, Vergel YB, Palmer S, et al. Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis. Heart. 2007;93:1244–50.PubMedCrossRefPubMedCentral

11.

Nielsen PH, Maeng M, Busk M, for the DANAMI-2 investigators, et al. Primary angioplasty versus fibrinolysis in acute myocardial infarction. Long-term follow-up in the Danish acute myocardial infarction-2 trial. Circulation. 2010;121:1484–91.PubMedCrossRef

12.

Zijlstra F, de Boer MJ. Should more hospitals in the Netherlands provide PCI without on-site surgery? Neth Heart J. 2007;15:171–2.PubMedCrossRefPubMedCentral

13.

Verweij L, Tra J, Engel J, Verheij RA, de Bruijne MC, Wagner C. Data quality issues impede comparability of hospital treatment delay performance indicators. Neth Heart J. 2015;23. DOI: 10.1007/s12471-015-0708-3

14.

Terkelsen CJ, Pinto DS, Thiele H, et al. 2012 ESC STEMI guidelines and reperfusion therapy: evidence base ignored, threatening optimal patient management. Heart. 2013;99:1154–6.PubMedCrossRefPubMedCentral

15.

Terkelsen CJ, Pinto D, Clemmensen P, et al. A response to the misrepresentation of the STEMI guidelines. Heart. 2013;99:1787–8.

16.

SWEDEHEART (Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies) Annual report. 2014.

17.

Brouwer MA, Martin JS, Maynard C, for the MITI Project Investigators, et al. Influence of early prehospital thrombolysis on mortality and event-free survival (the Myocardial Infarction Triage and Intervention [MITI] Randomized Trial). Am J Cardiol. 1996;78:497–502.PubMedCrossRef

18.

Kristensen SD, Laut KG, Fajadet J, on behalf of the European Association for Percutaneous Cardiovascular Interventions, et al. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries. Eur Heart J. 2014;35:1957–70.PubMedCrossRef

19.

Swaminathan RV, Wang TY, Kaltenbach LA, et al. Nonsystem reasons for delay in door-to-balloon time and associated in-hospital mortality: a report from the National Cardiovascular Data Registry. J Am Coll Cardiol. 2013;61:1688–95.PubMedCrossRef

20.

Terkelsen CJ, Jensen LO, Tilsted HH, et al. Health care system delay and heart failure in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: follow-up of population-based medical registry data. Ann Intern Med. 2011;155:361–7.PubMedCrossRef

21.

Bagai A, Dangas GD, Stone GW, Granger CB. Reperfusion strategies in acute coronary syndromes. Circ Res. 2014;114:1918–28.PubMedCrossRef

22.

Henriques JP, Haasdijk AP, Zijlstra F, Zwolle Myocardial Infarction Study Group. Outcome of primary angioplasty for acute myocardial infarction during routine duty hours versus during off-duty hours. J Am Coll Cardiol. 2003;41:2138–42.PubMedCrossRef

23.

Sorita A, Ahmed A, Starr SR, et al. Off-hour presentation and outcomes in patients with acute myocardial infarction: systematic review and meta-analysis. BMJ 2014;348:f7393.

24.

Søholm H, Kjaegaard J, Bro-Jeppesen J, et al. Prognostic implications of level-of-care at tertiary heart centers compared with other hospitals after resuscitation from out-of-hospital cardiac arrest. Circ Cardiovasc Qual Outcomes. 2015;8(3):268–76.

25.

Dumas F, Cariou A, Manzo-Silberman S, et al. Immediate percutaneous coronary intervention is associated with better survival after out-of-hospital cardiac arrest: insights from the PROCAT registry. Circ Cardiovasc Interv. 2010;3:200–7.PubMedCrossRef

26.

Gräsner JT, Meybohm P, Caliebe A, et al. Postresuscitation care with mild hypothermia and coronary intervention after out-of-hospital cardiopulmonary resuscitation: a prospective registry analysis. Crit Care. 2011;15:R61.PubMedCrossRefPubMedCentral

27.

Grines CL, Schreiber T. Primary percutaneous coronary intervention. The deception of delay. J Am Coll Cardiol. 2013;61:1696–7.PubMedCrossRef

28.

de Boer SP, Barnes EH, Westerhout CM, et al. High-risk patients with ST-elevation myocardial infarction derive greatest absolute benefit from primary percutaneous coronary intervention: results from the primary coronary angioplasty trialist versus thrombolysis (PCAT)-2 collaboration. Am Heart J. 2011;161:500–7.PubMedCrossRef

29.

De Luca G, Suryapranata H, Zijlstra F, et al. Symptom-onset-to-balloon time and mortality in patients with acute myocardial infarction treated by primary angioplasty. J Am Coll Cardiol. 2003;42:991–7.PubMedCrossRef

30.

De Luca G, van ’t Hof AW, De Boer MJ, et al. Time-to-treatment significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute myocardial infarction treated by primary angioplasty. Eur Heart J. 2004;25:1009–13.PubMedCrossRef

31.

Terkelsen CJ, Sorensen JT, Maeng M, et al. System delay and mortality among patients with STEMI treated with primary percutaneous coronary intervention. JAMA. 2010;304:763–71.PubMedCrossRef

Title: STEMI time delays: a clinical perspective
Editorial comment on the article by Verweij et al.
Authors: M-J. de Boer
F. Zijlstra
Publication date: 01-08-2015
Publisher: Bohn Stafleu van Loghum
Published in: Netherlands Heart Journal / Issue 9/2015
Print ISSN: 1568-5888
Electronic ISSN: 1876-6250
DOI: https://doi.org/10.1007/s12471-015-0728-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

STEMI time delays: a clinical perspective

Editorial comment on the article by Verweij et al.

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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