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Published in: Trials 1/2016

Open Access 01-12-2016 | Study protocol

START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a cluster-randomised controlled trial

Authors: Linda Kersten, Martin Prätzlich, Sandra Mannstadt, Katharina Ackermann, Gregor Kohls, Helena Oldenhof, Daniel Saure, Katrin Krieger, Beate Herpertz-Dahlmann, Arne Popma, Christine M. Freitag, Robert L. Trestman, Christina Stadler

Published in: Trials | Issue 1/2016

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Abstract

Background

In Europe, the number of females exhibiting oppositional defiant disorder (ODD) and conduct disorder (CD) is growing. Many of these females live in youth welfare institutions. Consequently, there is a great need for evidence-based interventions within youth welfare settings. A recently developed approach targeting the specific needs of girls with ODD and CD in residential care is START NOW. The aim of this group-based behavioural skills training programme is to specifically enhance emotional regulation capacities to enable females with CD or ODD to appropriately deal with daily-life demands. It is intended to enhance psychosocial adjustment and well-being as well as reduce oppositional and aggressive behaviour. We present the study protocol (version 4.1; 10 February 2016) of the FemNAT-CD intervention trial titled ‘Group-Based Treatment of Adolescent Female Conduct Disorders: The Central Role of Emotion Regulation’.

Methods/design

The study is a prospective, confirmatory, cluster-randomised, parallel-group, multi-centre, randomised controlled trial with 128 institutionalised female adolescents who fulfil the diagnostic criteria of ODD and/or CD. Institutions/wards will be randomised either to provide the 12-week skills training as an add-on intervention or to provide treatment as usual. Once the first cycle is completed, each institution will run a second cycle with the opposite condition. Primary endpoints are the pre-post change in number of CD/ODD symptoms as assessed by a standardised, semi-structured psychiatric interview (Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children–Present and Lifetime, CD/ODD section) between baseline and the end of intervention, as well as between baseline and a 3-month follow-up point. Secondary objectives include pre-post change in CD/ODD-related outcome measures, most notably emotional regulation on a behavioural and neurobiological level after completion of START NOW compared with treatment as usual.

Discussion

To our knowledge, this study is the first to date to systematically investigate the effectiveness of an adapted integrative psychosocial intervention designed for female adolescents with ODD and CD in youth welfare settings.

Trial registration

German Clinical Trials Register (DRKS) identifier: DRKS00007524. Registered on 18 December 2015 and with the World Health Organisation International Clinical Trials Registry Platform.
Appendix
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Literature
1.
Fernandez-Rivas A, Gonzalez-Torres MA. The economic crisis in Spain and its impact on the mental health of children and adolescents. Eur Child Adolesc Psychiatry. 2013;22(9):583–6.PubMedCrossRef
2.
American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013.CrossRef
3.
Fontaine N, Carbonneau R, Vitaro F, Barker ED, Tremblay RE. Research review: a critical review of studies on the developmental trajectories of antisocial behavior in females. J Child Psychol Psychiatry. 2009;50(4):363–85.PubMedCrossRef
4.
Gelhorn HL, Sakai JT, Price RK, Crowley TJ. DSM-IV conduct disorder criteria as predictors of antisocial personality disorder. Compr Psychiatry. 2007;48(6):529–38.PubMedPubMedCentralCrossRef
5.
Cohen MA, Piquero AR. New evidence on the monetary value of saving a high risk youth. J Quant Criminol. 2009;25(1):25–49.CrossRef
6.
7.
Berkout OV, Young JN, Gross AM. Mean girls and bad boys: recent research on gender differences in conduct disorder. Aggress Violent Behav. 2011;16(6):503–11.CrossRef
8.
Collishaw S, Maughan B, Goodman R, Pickles A. Time trends in adolescent mental health. J Child Psychol Psychiatry. 2004;45(8):1350–62.PubMedCrossRef
9.
Keenan K, Loeber R, Green S. Conduct disorder in girls: a review of the literature. Clin Child Fam Psychol Rev. 1999;2(1):3–19.PubMedCrossRef
10.
Maughan B, Rowe R, Messer J, Goodman R, Meltzer H. Conduct disorder and oppositional defiant disorder in a national sample: developmental epidemiology. J Child Psychol Psychiatry. 2004;45(3):609–21.PubMedCrossRef
11.
Ravens-Sieberer U, Erhart M, Wille N, Bullinger M, BELLA study group. Health-related quality of life in children and adolescents in Germany: results of the BELLA study. Eur Child Adolesc Psychiatry. 2008;17 Suppl 1:148–56.PubMedCrossRef
12.
Teplin LA, Abram KM, McClelland GM, Dulcan MK, Mericle AA. Psychiatric disorders in youth in juvenile detention. Arch Gen Psychiatry. 2002;59(12):1133–43.PubMedPubMedCentralCrossRef
13.
Javdani S, Sadeh N, Verona E. Expanding our lens: female pathways to antisocial behavior in adolescence and adulthood. Clin Psychol Rev. 2011;31(8):1324–48.PubMedPubMedCentralCrossRef
14.
Stadler C, Kröger A, Clement HW, Grasmann D. Störungen des Sozialverhaltens: Wirksamkeit des intensivtherapeutischen Behandlungsansatzes VIA. Kindheit und Entwicklung. 2012;21(2):103–13.CrossRef
15.
Stadler C, Manetsch M, Vriends N. Dialektisch-behaviorale Behandlungsansätze bei aggressiven Verhaltensstörungen. Z Kinder Jugendpsychiatr Psychother. 2016;44(6):443–54.PubMedCrossRef
16.
Natioinal Collaborating Centre for Mental Health; Social Care Institute for Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition, intervention and management. NICE Clinical Guidelines no. 158. Leicester: British Psychological Society and the Royal College of Psychiatrists; 2013.
17.
Weisz JR, Kazdin AE. Evidence-based psychotherapies for children and adolescents. 2nd ed. New York: Guilford Press; 2010.
18.
19.
Shelton D, Wakai S. A process evaluation of START NOW skills training for inmates with impulsive and aggressive behaviors. J Am Psychiatr Nurses Assoc. 2011;17(2):148–57.PubMed
20.
Monti PM, Kadden RM, Rohsenow DJ, Cooney NL, Abrams DB. Treating alcohol dependence: a coping skills training guide. New York: Guilford Press; 2002.
21.
Morgan RD, Flora DB. Group psychotherapy with incarcerated offenders: a research synthesis. Group Dy. 2002;6(3):203–18.CrossRef
22.
Botvin GJ, Griffin KW. Life skills training: empirical findings and future directions. J Prim Prev. 2004;25(2):211–32.CrossRef
23.
Feindler EL, Ecton RB. Adolescent anger control: cognitive-behavioral techniques. New York: Pergamon Press; 1986.
24.
Glick B, Gibbs JC. Aggression replacement training: a comprehensive intervention for aggressive youth. 3rd ed. Champaign: Research Press; 2010.
25.
Lochman JE, Wells KC. Effectiveness of the Coping Power Program and of classroom intervention with aggressive children: outcomes at a 1-year follow-up. Behav Ther. 2003;34(4):493–515.CrossRef
26.
Stadler C, Grasmann D, Fegert JM, Holtmann M, Poustka F, Schmeck K. Heart rate and treatment effect in children with disruptive behavior disorders. Child Psychiatry Hum Dev. 2008;39(3):299–309.PubMedCrossRef
27.
Morgenstern J, Morgan TJ, McCrady BS, Keller DS, Carroll KM. Manual-guided cognitive-behavioral therapy training: A promising method for disseminating empirically supported substance abuse treatments to the practice community. Psychol Addict Behav. 2001;15(2):83–8.PubMedCrossRef
28.
Miller WR, Rollnick S. Motivational interviewing: preparing people for change. 2nd ed. New York: Guilford; 2002.
29.
Chambers JC, Eccleston L, Day A, Ward T, Howells K. Treatment readiness in violent offenders: the influence of cognitive factors on engagement in violence programs. Aggress Violent Behav. 2008;13(4):276–84.CrossRef
30.
Howells K, Day A. Affective determinants of treatment engagement in violent offenders. Int J Offender Ther Comp Criminol. 2006;50(2):174–86.PubMedCrossRef
31.
Trupin EW, Stewart DG, Beach B, Boesky L. Effectiveness of a dialectical behaviour therapy program for incarcerated female juvenile offenders. Child Adolesc Mental Health. 2002;7(3):121–7.CrossRef
32.
33.
Dennis M, Godley SH, Diamond G, Tims FM, Babor T, Donaldson J, et al. The Cannabis Youth Treatment (CYT) Study: main findings from two randomized trials. J Subst Abuse Treat. 2004;27(3):197–213.PubMedCrossRef
34.
Diamond G, Godley SH, Liddle HA, Sampl S, Webb C, Tims FM, et al. Five outpatient treatment models for adolescent marijuana use: a description of the Cannabis Youth Treatment Interventions. Addiction. 2002;97 Suppl 1:70–83.PubMedCrossRef
35.
Colby SM, Monti PM, Barnett NP, Rohsenow DJ, Weissman K, Spirito A, et al. Brief motivational interviewing in a hospital setting for adolescent smoking: a preliminary study. J Consult Clin Psychol. 1998;66(3):574–8.PubMedCrossRef
36.
McCambridge J, Strang J. The efficacy of single‐session motivational interviewing in reducing drug consumption and perceptions of drug‐related risk and harm among young people: results from a multi‐site cluster randomized trial. Addiction. 2004;99(1):39–52.PubMedCrossRef
37.
Berg-Smith SM, Stevens VJ, Brown KM, Van Horn L, Gernhofer N, Peters E, et al. A brief motivational intervention to improve dietary adherence in adolescents. Health Educ Res. 1999;14(3):399–410.PubMedCrossRef
38.
Neumark-Sztainer DR, Friend SE, Flattum CF, Hannan PJ, Story MT, Bauer KW, et al. New moves—preventing weight-related problems in adolescent girls: a group-randomized study. Am J Prev Med. 2010;39(5):421–32.PubMedPubMedCentralCrossRef
39.
Channon SJ, Huws-Thomas MV, Rollnick S, Hood K, Cannings-John RL, Rogers C, et al. A multicenter randomized controlled trial of motivational interviewing in teenagers with diabetes. Diabetes Care. 2007;30(6):1390–5.PubMedCrossRef
40.
Carroll KM, Ball SA, Nich C, Martino S, Frankforter TL, Farentinos C, et al. Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: a multisite effectiveness study. Drug Alcohol Depend. 2006;81(3):301–12.PubMedCrossRef
41.
Davis TM, Baer JS, Saxon AJ, Kivlahan DR. Brief motivational feedback improves post-incarceration treatment contact among veterans with substance use disorders. Drug Alcohol Depend. 2003;69(2):197–203.PubMedCrossRef
42.
Stein LA, Monti PM, Colby SM, Barnett NP, Golembeske C, Lebeau-Craven R, et al. Enhancing substance abuse treatment engagement in incarcerated adolescents. Psychol Serv. 2006;3(1):25–34.PubMedPubMedCentralCrossRef
43.
Williams WH, Mewse AJ, Tonks J, Mills S, Burgess CN, Cordan G. Traumatic brain injury in a prison population: prevalence and risk for re-offending. Brain Inj. 2010;24(10):1184–8.PubMedCrossRef
44.
Fishbein D, Sheppard M, Hyde C, Hubal R, Newlin D, Serin R, et al. Deficits in behavioral inhibition predict treatment engagement in prison inmates. Law Hum Behav. 2009;33(5):419–35.PubMedCrossRef
45.
46.
Hawley CA. Reported problems and their resolution following mild, moderate and severe traumatic brain injury amongst children and adolescents in the UK. Brain Inj. 2003;17(2):105–29.PubMedCrossRef
47.
Linehan MM. Cognitive-behavioral treatment of borderline personality disorder. New York: Guilford Press; 1993.
48.
Berzins LG, Trestman RL. The development and implementation of dialectical behavior therapy in forensic settings. Int J Forensic Mental Health. 2004;3(1):93–103.CrossRef
49.
Quinn A, Shera W. Evidence-based practice in group work with incarcerated youth. Int J Law Psychiatry. 2009;32(5):288–93.PubMedCrossRef
50.
Lynch TR, Chapman AL, Rosenthal MZ, Kuo JR, Linehan MM. Mechanisms of change in dialectical behavior therapy: theoretical and empirical observations. J Clin Psychol. 2006;62(4):459–80.PubMedCrossRef
51.
Grawe K. Allgemeine Psychotherapie. In: Senf W, Broda M, editors. Praxis der Psychotherapie: Ein integratives Lehrbuch. 2nd ed. Stuttgart, Germany: Thieme; 2000. p. 314–25.
52.
Baer RA, editor. Mindfulness-based treatment approaches: clinician’s guide to evidence base and applications. 2nd ed. San Diego: Academic Press; 2014.
53.
McCann RA, Ball EM, Ivanoff A. DBT with an inpatient forensic population: the CMHIP forensic model. Cogn Behav Pract. 2000;7(4):447–56.CrossRef
54.
Nelson-Gray RO, Keane SP, Hurst RM, Mitchell JT, Warburton JB, Chok JT, et al. A modified DBT skills training program for oppositional defiant adolescents: promising preliminary findings. Behav Res Ther. 2006;44(12):1811–20.PubMedCrossRef
55.
Trupin EW, Steward DG, Beach B, Boesky L. Effectiveness of a dialectical behavior therapy program for incarcerated female juvenile offenders. Child Adolesc Ment Health. 2002;7(3):121–7.CrossRef
56.
Shelton D, Kesten K, Zhang W, Trestman R. Impact of a dialectic behavior therapy—corrections modified (DBT-CM) upon behaviorally challenged incarcerated male adolescents. J Child Adolesc Psychiatr Nurs. 2011;24(2):105–13.PubMedPubMedCentralCrossRef
57.
Napoli M, Krech PR, Holley LC. Mindfulness training for elementary school students: the attention academy. J Appl Sch Psychol. 2005;21(1):99–125.CrossRef
58.
Bögels S, Hoogstad B, van Dun L, de Schutter S, Restifo K. Mindfulness training for adolescents with externalizing disorders and their parents. Behav Cogn Psychother. 2008;36(2):193–209.CrossRef
59.
Singh NN, Lancioni GE, Singh Joy SD, Winton ASW, Sabaawi M, Wahler RG, et al. Adolescents with conduct disorder can be mindful of their aggressive behavior. J Emot Behav Disord. 2007;15(1):56–63.CrossRef
60.
van de Weijer-Bergsma E, Formsma AR, de Bruin EI, Bögels SM. The effectiveness of mindfulness training on behavioral problems and attentional functioning in adolescents with ADHD. J Child Fam Stud. 2012;21(5):775–87.PubMedCrossRef
61.
Ford JD, Cruz-St. Juste M. Trauma affect regulation: guide for education and therapy (TARGET-A/G version 2.1): 10-session experiential trauma-focused psychoeducational group therapy for adolescents. Farmington: University of Connecticut Health Center; 2006.
62.
van Vugt E, Lanctôt N, Paquette G, Collin-Vézina D, Lemieux A. Girls in residential care: from child maltreatment to trauma-related symptoms in emerging adulthood. Child Abuse Negl. 2014;38(1):114–22.PubMedCrossRef
63.
Kersten L, Cislo AM, Lynch M, Shea K, Trestman RL. Evaluating START NOW: a skills-based psychotherapy for inmates of correctional systems. Psychiatr Serv. 2016;67(1):37–42.PubMedCrossRef
64.
Cislo AM, Trestman RL. Psychiatric hospitalization after participation in START NOW. Psychiatr Serv. 2016;67(1):143.PubMedCrossRef
65.
Stadler C, Kersten L, Prätzlich M. Störung des Sozialverhaltens mit fehlenden prosozialen Emotionen: Sind vorliegende Behandlungsprogramme weniger wirksam? PSYCH up2date. 2015;9(4):225–35.
66.
67.
Bagner DM, Graziano PA, Jaccard J, Sheinkopf SJ, Vohr BR, Lester BM. An initial investigation of baseline respiratory sinus arrhythmia as a moderator of treatment outcome for young children born premature with externalizing behavior problems. Behav Ther. 2012;43(3):652–65.PubMedPubMedCentralCrossRef
68.
McRae K, Gross JJ, Weber J, Robertson ER, Sokol-Hessner P, Ray RD, et al. The development of emotion regulation: an fMRI study of cognitive reappraisal in children, adolescents and young adults. Soc Cogn Affect Neurosci. 2012;7(1):11–22.PubMedPubMedCentralCrossRef
69.
Ochsner KN, Silvers JA, Buhle JT. Functional imaging studies of emotion regulation: a synthetic review and evolving model of the cognitive control of emotion. Ann N Y Acad Sci. 2012;1251:E1–24.PubMedPubMedCentralCrossRef
70.
Ochsner KN, Ray RD, Cooper JC, Robertson ER, Chopra S, Gabrieli JD, et al. For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion. Neuroimage. 2004;23(2):483–99.PubMedCrossRef
71.
Ochsner KN, Bunge SA, Gross JJ, Gabrieli JD. Rethinking feelings: an FMRI study of the cognitive regulation of emotion. J Cogn Neurosci. 2002;14(8):1215–29.PubMedCrossRef
72.
Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P, et al. Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry. 1997;36(7):980–8.PubMedCrossRef
73.
Delmo C, Weiffenbach O, Gabriel M, Stadler C, Poustka F. Kiddie-SADS-Present and Lifetime Version (K-SADS-PL) [German adaptation]. Frankfurt: University of Frankfurt; 2000.
74.
Raine A, Dodge K, Loeber R, Gatzke-Kopp L, Lynam D, Reynolds C, et al. The Reactive-Proactive Aggression Questionnaire: differential correlates of reactive and proactive aggression in adolescent boys. Aggress Behav. 2006;32(2):159–71.PubMedPubMedCentralCrossRef
75.
Rusby JC. Perpetration and Victimization of Relational Aggression Questionnaire, Self-Report. Eugene, OR: Oregon Research Institute; 2009.
76.
Arbeitsgruppe Deutsche Child Behaviour Checklist, Fragebogen für Jugendlichen. Deutsche Bearbeitung des Youth Self Report (YSR), Einführung und Anleitung zur Handauswertung. 2. Auflage mit deutschen Normen bearbeitet von Döpfner M, Plück J, Melchers P, Heim K. Cologne, Germany: Arbeitsgruppe Kinder-, Jugend- und Familiendiagnostik; 1998.
77.
Stringaris A, Goodman R, Ferdinando S, Razdan V, Muhrer E, Leibenluft E, et al. The Affective Reactivity Index: a concise irritability scale for clinical and research settings. J Child Psychol Psychiatry. 2012;53(11):1109–17.PubMedPubMedCentralCrossRef
78.
Andershed H, Kerr M, Stattin H, Levander S. Psychopathic traits in non-referred youths: initial test of a new assessment tool. In: Blaauw E, Sheridaan L, editors. Psychopaths: current international perspectives. The Hague, The Netherlands: Elsevier; 2002. p. 131–58.
79.
Essau CA, Sasagawa S, Frick PJ. Callous-unemotional traits in a community sample of adolescents. Assessment. 2006;13(4):454–69.PubMedCrossRef
80.
Yudofsky SC, Silver JM, Jackson W, Endicott J, Williams D. The Overt Aggression Scale for the objective rating of verbal and physical aggression. Am J Psychiatry. 1986;143(1):35–9.PubMedCrossRef
81.
Gratz KL, Roemer L. Multidimensional assessment of emotion regulation and dysregulation: development, factor structure, and initial validation of the difficulties in emotion regulation scale. J Psychopathol Behav Assess. 2004;26(1):41–54.CrossRef
82.
McDougall J, King G. Goal attainment scaling: description, utility, and applications in pediatric therapy services. London, ON, Canada: Thames Valley Children’s Centre; 2007.
83.
Huebner ES, Drane W, Valois RF. Levels and demographic correlates of adolescent life satisfaction reports. Sch Psychol Int. 2000;21(3):281–92.CrossRef
84.
Fengler J, Sanz A. Ausgebrannte Teams: Burnout-Prävention und Salutogenese, vol. 235. Stuttgart, Germany: Klett-Cotta; 2011.
85.
Hagemann W, Geuenich K. Burnout-Screening-Skalen (BOSS). Göttingen, Germany: Hogrefe; 2009.
86.
Schwarzer R, Schmitz G. Skala zur Lehrer-Selbstwirksamkeitserwartung: Skalen zur Erfassung von Lehrer-und Schülermerkmalen. Berlin: Freie Universität Berlin; 1999. p. 60–1.
87.
Fengler J, Sanz A, editors. Ausgebrannte Teams: Burnout-Prävention und Salutogenese. Stuttgart, Germany: Klett-Cotta; 2011.
88.
Hagemann W, Geuenich K. Burnout-Screening-Skalen (BOSS) manual. Göttingen, Germany: Hogrefe; 2009.
89.
Grisso T, Barnum R. Massachusetts Youth Screening Instrument, version 2: MAYSI-2: user’s manual and technical report. Revth ed. Sarasota: Professional Resource Press; 2006.
90.
Petersen AC, Crockett L, Richards M, Boxer A. A self-report measure of pubertal status: reliability, validity, and initial norms. J Youth Adolesc. 1988;17(2):117–33.PubMedCrossRef
91.
Schwab-Stone M, Chen C, Greenberger E, Silver D, Lichtman J, Voyce C. No safe haven. II: The effects of violence exposure on urban youth. J Am Acad Child Adolesc Psychiatry. 1999;38(4):359–67.PubMedCrossRef
92.
Petermann F, Petermann U. Wechsler Intelligence Scale for Children (WISC-IV). 4th ed. Frankfurt, Germany: Pearson Assessment and Information; 2011.
93.
Zanarini MC, Frankenburg FR, Sickel AE, Yong L. The Diagnostic Interview for DSM-IV Personality Disorders (DIPD-IV). Belmont, MA: McLean Hospital; 1996. p. 340.
94.
Bifulco A, Brown GW, Harris TO. Childhood Experience of Care and Abuse (CECA): a retrospective interview measure. J Child Psychol Psychiatry. 1994;35(8):1419–35.PubMedCrossRef
95.
Tottenham N, Hare TA, Casey BJ. Behavioral assessment of emotion discrimination, emotion regulation, and cognitive control in childhood, adolescence, and adulthood. Front Psychol. 2011;2:39.PubMedPubMedCentralCrossRef
96.
Newman JP, Schmitt WA. Passive avoidance in psychopathic offenders: a replication and extension. J Abnorm Psychol. 1998;107(3):527–32.PubMedCrossRef
97.
Scarpa A, Haden SC, Tanaka A. Being hot-tempered: Autonomic, emotional, and behavioral distinctions between childhood reactive and proactive aggression. Biol Psychol. 2010;84(3):488–96.PubMedCrossRef
98.
Wang D, Szyf M, Benkelfat C, Provençal N, Turecki G, Caramaschi D, et al. Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression. PLoS One. 2012;7(6):e39501.PubMedPubMedCentralCrossRef
99.
de Wied M, van Boxtel A, Matthys W, Meeus W. Verbal, facial and autonomic responses to empathy-eliciting film clips by disruptive male adolescents with high versus low callous-unemotional traits. J Abnorm Child Psychol. 2012;40(2):211–23.PubMedCrossRef
100.
Beauchaine TP, Gartner J, Hagen B. Comorbid depression and heart rate variability as predictors of aggressive and hyperactive symptom responsiveness during inpatient treatment of conduct-disordered, ADHD boys. Aggress Behav. 2000;26(6):425–41.CrossRef
101.
Månsson KN, Frick A, Boraxbekk CJ, Marquand AF, Williams SC, Carlbring P, et al. Predicting long-term outcome of Internet-delivered cognitive behavior therapy for social anxiety disorder using fMRI and support vector machine learning. Transl Psychiatry. 2015;5:e530.PubMedPubMedCentralCrossRef
102.
Hedeker D, Gibbons RD, Flay BR. Random-effects regression models for clustered data with an example from smoking prevention research. J Consult Clin Psychol. 1994;62(4):757–65.PubMedCrossRef
103.
Lancaster GA, Campbell MJ, Eldridge S, Farrin A, Marchant M, Muller S, et al. Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions. Stat Methods Med Res. 2010;19(4):349–77.PubMedCrossRef
104.
Hedges LV. Estimation of effect size from a series of independent experiments. Psychol Bull. 1982;92(2):490–9.CrossRef
105.
Schmid M, Goldbeck L, Nuetzel J, Fegert JM. Prevalence of mental disorders among adolescents in German youth welfare institutions. Child Adolesc Psychiatr Ment Health. 2008;2(1):2.CrossRef
106.
Ford T, Vostanis P, Meltzer H, Goodman R. Psychiatric disorder among British children looked after by local authorities: comparison with children living in private households. Br J Psychiatry. 2007;190:319–25.PubMedCrossRef
107.
De Swart JJW, Van den Broek H, Stams GJJM, Asscher JJ, Van der Laan PH, Holsbrink-Engels GA, et al. The effectiveness of institutional youth care over the past three decades: a meta-analysis. Child Youth Serv Rev. 2012;34(9):1818–24.CrossRef
108.
Mohr DC, Spring B, Freedland KE, Beckner V, Arean P, Hollon SD, et al. The selection and design of control conditions for randomized controlled trials of psychological interventions. Psychother Psychosom. 2009;78(5):275–84.PubMedCrossRef
Metadata
Title
START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a cluster-randomised controlled trial
Authors
Linda Kersten
Martin Prätzlich
Sandra Mannstadt
Katharina Ackermann
Gregor Kohls
Helena Oldenhof
Daniel Saure
Katrin Krieger
Beate Herpertz-Dahlmann
Arne Popma
Christine M. Freitag
Robert L. Trestman
Christina Stadler
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Trials / Issue 1/2016
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-016-1705-6

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