Standard pulse contour methods are not applicable in animals

Excerpt

Sir: I read the paper of Gunn and colleagues [1] evaluating the pulse contour method in animals with great interest, yet also with growing disappointment. This although the authors show great skill in performing animal experiments. Being closely associated with the development of pulse contour methods, I was alarmed by the third paragraph in their introduction. They state that the original Wesseling algorithm [2] was implemented in the PiCCO software version 1.0.14 (Pulsion, Munich, Germany) used in this study. Next they describe the characteristics of the modelflow pulse contour method which indeed was the topic of the cited paper. This citation is wrong and tendentious, because the authors implicitly try to convince the readers that the conclusions of their paper also count for the modelflow method. …