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22-03-2022 | Squamous Cell Carcinoma of the Oral Cavity | ASO Author Reflections

ASO Author Reflections: The Pursuit of Prognostic Factors to Fine-Tune Treatment Decisions in Patients with Oral Cavity Carcinoma

Authors: José F. Carrillo, MD, Alejandro Avilés-Salas, MD, Roberto Herrera-Goepfert, MD, Gabriela Figueroa-González, MD, PhD, Luis F. Oñate-Ocaña, MD, MSc

Published in: Annals of Surgical Oncology | Issue 7/2022

Excerpt

Squamous cell carcinoma of the oral cavity (SCCOC) is associated with smoking and alcoholism, as with microbiota and oral hygiene habits. At present, the role of the human papilloma virus as an etiological agent in SCCOC is poorly understood.¹ A solid definition of prognostic factors, other than the TNM staging system, has not been widely recognized to allow fine-tuning patient prognoses and, consequently, the requirements for therapy intensification or deescalation. …

Panarese I, Aquino G, Ronchi A, et al. Oral and oropharyngeal squamous cell carcinoma: prognostic and predictive parameters in the etiopathogenetic route. Expert Rev Anticancer Ther. 2019;19:105–19. https://doi.org/10.1080/14737140.2019.1561288.CrossRefPubMed

Brandwein-Gensler M, Teixeira MS, Lewis CM, et al. Oral squamous cell carcinoma: histologic risk assessment, but not margin status, is strongly predictive of local disease-free and overall survival. Am J Surg Pathol. 2005;29:167–78. https://doi.org/10.1097/01.pas.0000149687.90710.21.CrossRefPubMed

Schwam ZG, Judson BL. Improved prognosis for patients with oral cavity squamous cell carcinoma: analysis of the National Cancer Database 1998–2006. Oral Oncol. 2016;52:45–51. https://doi.org/10.1016/j.oraloncology.2015.10.012.CrossRefPubMed

Figueroa-González G, Carrillo-Hernández JF, Perez-Rodriguez I, et al. Negative regulation of Serine Threonine Kinase 11 (STK11) through miR-100 in head and neck cancer. Genes (Basel). 2020;11:1058. https://doi.org/10.3390/genes11091058.CrossRefPubMedCentral

Carrillo JF, Cruz-Romero Ch, Avilés-Salas A, et al. LKB-1 expression and high-risk histopathology are independent prognostic factors for patients with oral cavity carcinoma. Ann Surg Oncol. 2022. https://doi.org/10.1245/s10434-022-11544-x.

Title: ASO Author Reflections: The Pursuit of Prognostic Factors to Fine-Tune Treatment Decisions in Patients with Oral Cavity Carcinoma
Authors: José F. Carrillo, MD
Alejandro Avilés-Salas, MD
Roberto Herrera-Goepfert, MD
Gabriela Figueroa-González, MD, PhD
Luis F. Oñate-Ocaña, MD, MSc
Publication date: 22-03-2022
Publisher: Springer International Publishing
Keywords: Squamous Cell Carcinoma of the Oral Cavity
Squamous Cell Carcinoma of the Oral Cavity
Oral Cancer
Oral Cavity Carcinoma
Published in: Annals of Surgical Oncology / Issue 7/2022
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-022-11598-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

ASO Author Reflections: The Pursuit of Prognostic Factors to Fine-Tune Treatment Decisions in Patients with Oral Cavity Carcinoma

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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