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Targeted Oncology

Issue 5/2017

Content (12 Articles)

Leading Article

Targeting the PD-1/PD-L1 Immune Checkpoint in EGFR-Mutated or ALK-Translocated Non-Small-Cell Lung Cancer

Olivier Bylicki, Nicolas Paleiron, Jacques Margery, Florian Guisier, Alain Vergnenegre, Gilles Robinet, Jean-Bernard Auliac, Radj Gervais, Christos Chouaid

Open Access Review Article

Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies

Aaron Simpson, Wilfride Petnga, Valentine M. Macaulay, Ulrike Weyer-Czernilofsky, Thomas Bogenrieder

Open Access Review Article

Bevacizumab in Colorectal Cancer: Current Role in Treatment and the Potential of Biosimilars

Lee S. Rosen, Ira A. Jacobs, Ronald L. Burkes

Review Article

Predictive Markers of Response to Everolimus and Sunitinib in Neuroendocrine Tumors

Diana Martins, Francesca Spada, Ioana Lambrescu, Manila Rubino, Chiara Cella, Bianca Gibelli, Chiara Grana, Dario Ribero, Emilio Bertani, Davide Ravizza, Guido Bonomo, Luigi Funicelli, Eleonora Pisa, Dario Zerini, Nicola Fazio

Review Article

Targeting the Wnt Pathway in Cancer: A Review of Novel Therapeutics

Roya Tabatabai, Yuliya Linhares, David Bolos, Monica Mita, Alain Mita

Open Access Original Research Article

Dose and Schedule Selection of the Oral Proteasome Inhibitor Ixazomib in Relapsed/Refractory Multiple Myeloma: Clinical and Model-Based Analyses

Neeraj Gupta, Huyuan Yang, Michael J. Hanley, Steven Zhang, Rachael Liu, Shaji Kumar, Paul G. Richardson, Tomas Skacel, Karthik Venkatakrishnan

Original Research Article

A Phase II Multicentre, Open-Label, Proof-of-Concept Study of Tasquinimod in Hepatocellular, Ovarian, Renal Cell, and Gastric Cancers

Bernard Escudier, Sandrine Faivre, Eric Van Cutsem, Nathalie Germann, Jean-Christophe Pouget, Ruth Plummer, Ignace Vergote, Fiona Thistlethwaite, Georg A. Bjarnason, Robert Jones, Helen Mackay, Julien Edeline, Laetitia Fartoux, Hal Hirte, Amit Oza

Original Research Article

EGFR Mutation Testing of non-squamous NSCLC: Impact and Uptake during Implementation of Testing Guidelines in a Population-Based Registry Cohort from Northern New Zealand

Mark McKeage, Mark Elwood, Sandar Tin Tin, Prashannata Khwaounjoo, Phyu Aye, Angie Li, Karen Sheath, Phillip Shepherd, George Laking, Nicola Kingston, Christopher Lewis, Donald Love

Original Research Article

The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells

Leisi Zhang, Yong Zhou, Kai Chen, Pengcheng Shi, Yin Li, Manman Deng, Zhiwu Jiang, Xiangmeng Wang, Peng Li, Bing Xu

Short Communication

Lung Adenocarcinoma Survival in EGFR-Mutated African-Caribbean Patients: A Multicenter Study in the French West Indies

Nicolas Leduc, Vincent Atallah, Moustapha Agossou, Vincent Vinh-Hung, Mathieu Orre, Paul Sargos, Vincent Molinie

Short Communication

A Combination of Testosterone and White Blood Cell Count as a Predictive Factor of Overall Survival in Localized Prostate Cancer

Daniel Taussky, Denis Souliéres, Laurent Azoulay, Hui Yin, Houda Bahig, Jean-Paul Bahary, Guila Delouya

Erratum

Erratum to: Is 1,25-Dihydroxyvitamin D3 Receptor Expression a Potential Achilles’ Heel of CD44+ Oral Squamous Cell Carcinoma Cells?

Martin Grimm, Beshr Shokri, Dorothea Alexander, Adelheid Munz, Juergen Hoffmann, Siegmar Reinert

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine