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Neurotherapeutics

Issue 2/2009

Nontraditional Epilepsy Treatment Approaches

Content (28 Articles)

Editorial

Nontraditional epilepsy treatment approaches

Michael A. Rogawski, Gregory L. Holmes

Theme 1: Brain Stimulation and Cooling

Electrical stimulation for the treatment of epilepsy

Paul Boon, Robrecht Raedt, Veerle de Herdt, Tine Wyckhuys, Kristl Vonck

Theme 1: Brain Stimulation and Cooling

Vagus nerve stimulation in the treatment of refractory epilepsy

Andrew H. Milby, Casey H. Halpern, Gordon H. Baltuch

Theme 1: Brain Stimulation and Cooling

Intracranial stimulation therapy for epilepsy

Tara L. Skarpaas, Martha J. Morrell

Theme 1: Brain Stimulation and Cooling

Noninvasive brain stimulation protocols in the treatment of epilepsy: Current state and perspectives

Michael A. Nitsche, Walter Paulus

Theme 1: Brain Stimulation and Cooling

The therapeutic potential of focal cooling for neocortical epilepsy

Steven M. Rothman

Theme 1: Brain Stimulation and Cooling

Commentary: Physical approaches for the treatment of epilepsy: Electrical and magnetic stimulation and cooling

Wolfgang Löscher, Andrew J. Cole, Michael J. McLean

Theme 2: Cell Therapy

Embryonic stem cell-derived neural precursor grafts for treatment of temporal lobe epilepsy

Xu Maisano, Joseph Carpentino, Sandy Becker, Robert Lanza, Gloster Aaron, Laura Grabel, Janice R. Naegele

Theme 2: Cell Therapy

Commentary: The prospect of cell-based therapy for epilepsy

Arnold R. Kriegstein, Asla Pitkänen

Theme 3: Gene Therapy

Neuropeptide Y overexpression using recombinant adenoassociated viral vectors

Francesco Noé, Angelisa Frasca, Claudia Balducci, Mirjana Carli, Gunther Sperk, Francesco Ferraguti, Asla Pitkänen, Ross Bland, Helen Fitzsimons, Matthew During, Annamaria Vezzani

Theme 3: Gene Therapy

Alteration of epileptogenesis genes

Amy R. Brooks-Kayal, Yogendra H. Raol, Shelley J. Russek

Theme 4: Novel Delivery Approach

Nanotechnology for delivery of drugs to the brain for epilepsy

Margaret F. Bennewitz, W. Mark Saltzman

Theme 4: Novel Delivery Approach

Intraventricular and intracerebral delivery of anti-epileptic drugs in the kindling model

Juan A. Barcia, José M. Gallego

Theme 4: Novel Delivery Approach

Convection-enhanced delivery in the treatment of epilepsy

Michael A. Rogawski

Theme 4: Novel Delivery Approach

Intranasal delivery of antiepileptic medications for treatment of seizures

Daniel P. Wermeling

Theme 4: Novel Delivery Approach

Attenuation of kindled seizures by intranasal delivery of neuropeptide-loaded nanoparticles

Michael J. Kubek, Abraham J. Domb, Michael C. Veronesi

Theme 4: Novel Delivery Approach

Developing novel antiepileptic drugs: Characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models

H. Steve White, Erika A. Scholl, Brian D. Klein, Sean P. Flynn, Timothy H. Pruess, Brad R. Green, Liuyin Zhang, Grzegorz Bulaj

Theme 4: Novel Delivery Approach

Commentary: Novel delivery approaches for antiepileptic drugs: Hope and hurdles

Dieter Schmidt, Gregory L. Holmes

Theme 5: Hormonal and Dietary Therapy

Hormonal therapies: Progesterone

Andrew G. Herzog

Theme 5: Hormonal and Dietary Therapy

Neurosteroid replacement therapy for catamenial epilepsy

Doodipala S. Reddy, Michael A. Rogawski

Theme 5: Hormonal and Dietary Therapy

The ketogenic diet: Proposed mechanisms of action

Kirk Nylen, Sergei Likhodii, W. McIntyre Burnham

Theme 5: Hormonal and Dietary Therapy

Ketogenic diets: Evidence for short- and long-term efficacy

Eric H. Kossoff, Jong M. Rho

Theme 5: Hormonal and Dietary Therapy

Botanicals and herbs: A traditional approach to treating epilepsy

Steven C. Schachter

Theme 5: Hormonal and Dietary Therapy

Commentary: Hormones, diet, and botanicals

Jerome Engel, Solomon L. Moshé