Issue 5/2010
Special Issue: Cardiovascular Therapeutic Discovery; Guest Editors: Burns C. Blaxall and Anthony J. Muslin
Content (18 Articles)
Cardiovascular Drug Discovery in the Academic Setting: Building Infrastructure, Harnessing Strengths, and Seeking Synergies
Stephen J. Gardell, Gregory P. Roth, Daniel P. Kelly
Drug Discovery in a Multidimensional World: Systems, Patterns, and Networks
Joel T. Dudley, Eric Schadt, Marina Sirota, Atul J. Butte, Euan Ashley
Delivering Regenerative Cues to the Heart: Cardiac Drug Delivery by Microspheres and Peptide Nanofibers
Jay C. Sy, Michael E. Davis
Protein Therapeutics for Cardiac Regeneration after Myocardial Infarction
Vincent F. M. Segers, Richard T. Lee
Injectable Materials for the Treatment of Myocardial Infarction and Heart Failure: The Promise of Decellularized Matrices
Jennifer M. Singelyn, Karen L. Christman
Development of Hydrogen Sulfide-Based Therapeutics for Cardiovascular Disease
Benjamin L. Predmore, David J. Lefer
βARKct: A Therapeutic Approach for Improved Adrenergic Signaling and Function in Heart Disease
Henriette Brinks, Walter J. Koch
Targeting Cyclic Nucleotide Phosphodiesterase in the Heart: Therapeutic Implications
Clint L. Miller, Chen Yan
TRP-ing up Heart and Vessels: Canonical Transient Receptor Potential Channels and Cardiovascular Disease
Janelle Rowell, Norimichi Koitabashi, David A. Kass
S100A1: A Multifaceted Therapeutic Target in Cardiovascular Disease
David Rohde, Julia Ritterhoff, Mirko Voelkers, Hugo A. Katus, Thomas G. Parker, Patrick Most
Our Expanding View of Platelet Functions and Its Clinical Implications
Christopher Ombrello, Robert C. Block, Craig N. Morrell
Improved Function and Myocardial Repair of Infarcted Heart by Intracoronary Injection of Mesenchymal Stem Cell-Derived Growth Factors
Ba-Khoi Nguyen, Simon Maltais, Louis P. Perrault, Jean-François Tanguay, Jean-Claude Tardif, Louis-Mathieu Stevens, Mélanie Borie, François Harel, Samer Mansour, Nicolas Noiseux
Extreme Respiratory Sinus Arrhythmia Enables Overwintering Black Bear Survival—Physiological Insights and Applications to Human Medicine
Timothy G. Laske, Henry J. Harlow, David L. Garshelis, Paul A. Iaizzo
Modulation of Gene Expression by Polyalthia longifolia in Postmenopausal Women with Coronary Artery Disease: An In Vitro Study
Anupam Mittal, Nitin Mahajan, Rajesh Vijayvergiya, Veena Dhawan
Risk Factors Preceding Type 2 Diabetes and Cardiomyopathy
Shamjeet Singh, Sanjiv Dhingra, Dan D. Ramdath, Sudesh Vasdev, Vicki Gill, Pawan K. Singal